Update: Chinese Researchers Finish Sequencing the Giant Panda Genome

China's Beijing Genomics Institute in Shenzhen announced that it has mapped the entire genetic code for the giant panda using DNA sequencing and analysis equipment from San Diego-based Illumina. The project began in mid 2008 and was completed by Jan.2009.

The panda at the center of this discovery is Jingjing, who lives in China's Chengdu Panda Breeding Research Center and was the mascot for the 2008 Beijing Olympics. The genetic information from Jingjing is expected to be complemented in the future with genetic information from other pandas.

Scientists hope to use the data from the sequencing project to better understand panda biology and reproduction. Giant pandas are difficult to breed in captivity and are currently on the endangered species list.

In China, the panda's genome sequencing was ranked by the Chinese government as one of the top 10 technology achievements of the year, right up there with the nation's space shuttle and the completion of the Tibetan railway.

Until next time...

Good Luck and Good Job Hunting!!!!!!!

 

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When Applying for Jobs Online Simply Isn't Enough

Back in the late 1990s, applying for jobs online was all the rage! The technology was new and fresh and applying for jobs online was fast and easy. Companies raced to build corporate websites for prospective job applicants, major job boards like Monster and Careerbuilder were launched and human resources professionals though they were ushering in a “new era of employee recruitment and retention.” While applying for jobs online once seemed like a panacea for both job seekers and corporate employers, it never has lived up to all the fanfare and hype!

There is no question that applying for jobs online is quick, easy and most importantly emotionally gratifying. Paradoxically, these are the very qualities that have almost rendered the practice useless when it comes to finding a new job. Before applying for jobs online became de rigueur, large numbers of qualified, prospective employees were hired into new jobs. Unfortunately, these days’ most corporate websites and job boards are swamped by unqualified applicants who submit their resumes when ever and where ever they can! This has prompted many companies and job board site to automate their applicant screening processes—which, in many cases, fail to discriminate between qualified and unqualified job applicants. Frequently, because of the sheer volume of applicants, many companies no longer acknowledge receipt of job applications. While this practice is unprofessional in my opinion, it sends a subliminal—if not obvious message—to applicants that the likelihood of winning the job is remote. It is not uncommon for job applicants to never hear from a company after they have hit the send button to submit a job application.

So, if applying for jobs online isn’t the answer, what should jobseekers do to find gainful employment? Like it or not, the best way to find a new job is through networking. The advent of social networking sites like Facebook, Linked In and BioCrowd makes networking less daunting than it used to be. However, it is important to note, that online networking alone won’t be sufficient! Unfortunately, (for some of you anyway), interacting with people in real life will be required! The best way to begin networking is to use Google (or your favorite search engine) to identify companies or institutions that are looking for applicants with your skills and qualifications. Next, work hard to find a contact at a company who is willing to support your application or at least, forward it to an appropriate hiring manager. If you don’t know anybody at the company ask friends or relatives if they do. If this doesn’t work, post a notice on Facebook or Linked In asking if anybody in your network can provide a contact name or phone number of a hiring manager at the company you are interested in. If this also proves to be unsuccessful, you can run at Internet search on a particular advertised position or go to a company website to find the name of a hiring manager. However, to avert an avalanche of inquiries about online job postings, many companies no longer list the names of hiring managers on their websites. If all else fails, you can always put in a call into human resources and ask for more information about a job with the hope of getting the hiring manager’s name.

Once you obtain the name of a hiring manager, send an e-mail message indicating your interesting the position along with an attached resume/curriculum vitae. One note of caution; managers are usually inundated with e-mail messages (many which remain unanswered) and often have their spam filters set on high. Consequently, it may be prudent to also send a hiring manager an old fashioned cover letter and curriculum vitae authority using traditional or overnight mail delivery.

While networking to get an employee referral for a job remains the best way to get your “foot-in-the-door” at most companies, the referral channels, like almost all others, are also extremely clogged. This may require a direct phone call to a hiring manager to inquire about whether or not to apply for a job or to check on the progress of an application. That said, use this approach wisely—some managers may think that this shows initiative (and will pull your resume from the resume heap) while others may be offended or annoyed by your boldness. Nevertheless, once you make the call, DO NOT call back unless you are advised to do so. If the company is interested in you as a job candidate, they will contact you after they have had sufficient time to review your application.

While companies continue to advertise positions, the best way to land a new job is through word of mouth. This is because many companies don’t advertise all open positions and some companies run ads even though they are not hiring. Nevertheless, building a solid network of contacts and friends (both online and in real life) is critical for successful job searches.

In today’s difficult economy it may be prudent to employ a multifaceted job search strategy that includes a mix of networking, job boards and online applications. Also, it is important to cast as wide a job net as possible and not limit your search to a specific job type—especially if you have skills  and qualifications that cut across disciplines. Finally, I always tell prospective job candidates that looking for a new job must be a “full time endeavor.” Devoting less than a full time effort to your job search will likely yield disappointing results!

Until next time….

Good Luck and Good Job Hunting!!!!!!!!

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Is Biotechnology in Your Future?

Despite its humble beginnings in the late 1970s, the biotechnology industry has transformed itself into one of the most vibrant sectors of the American economy. Pharmaceutical companies, once the bell weather of the life sciences industry, have finally conceded that biotechnology and not small molecules are the industry’s future!

While growth of the biotechnology industry has slowed somewhat in the past couple of years—mainly because of the recession—it still represents a viable career option for students interested in the biological sciences. Contrary to popular belief, a PhD degree is no longer required to gain employment in the biotechnology industry. The PhD degree option is slowly being replaced by biotechnology masters and undergraduate degrees and certificate programs readily available at many two year colleges. Put simply, there is a decreasing demand for PhDs at many life sciences companies—mostly because of technological advances and a growing reliance on outsourcing to carry out drug discovery and development. However, the demand for non-PhD employees with solid biotechnology backgrounds particularly in the areas of regulatory affairs, licensing, business development, medical communications, health informatics and biomanufacturing is rising.

For many students (especially high school and undergraduates), the plethora of biotechnology degree and certificate programs can be overwhelming. With this in mind, I came across a cool website called Biotechnology Degree Guide which helps students decide which program is right for them. The site is run by Webster Jorgensen who sent me the following information about the site.

“Biotechnology Degree Guide was developed to be a complete and comprehensive guide for finding colleges, universities and technical schools offering biotech and related programs. The site also features a rating system that allows registered users to rate various biotechnology programs. This feature was added to help separate the great programs from the not-sop-great ones. In the future, we plan to start highlighting "Hidden Gem" programs section that helps schools with lower profiles and great programs receive more exposure. The sites members section is open to prospective students, students, professionals, teachers and biotech hobbyists.  A social media component is planned for the future.”

While the Biotechnology Degree Guide may not answer all of your questions, it certainly is a good place to start when considering a career in biotechnology!

Until next time...

Good Luck and Good Job Hunting!!!!!!!!!!

 

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Foldit! Who Said Learning Protein Biochemistry Wasn't Fun?

While surfing the web, I came upon a cool website called Foldit. Foldit is an online competitive, interactive protein folding game that showcases the principles and properties of protein biochemistries.

The game, originally created by David Baker, Zoran Popović and David Salesin, works like this. Players are given a ribbon model of a protein made up of amino acids. Players use the cursor to grab, bend, pull, and wiggle the chain of amino acids anywhere along its length, folding the protein into its optimum shape. The only rules are based on physics—opposite charges attract, atomic bonds have limited angles of rotation, and the parts of the molecule that stick to water tend to point outward. The closer your model's properties adhere to those rules, the more points you get. The goal of the game was to get large numbers of players to work on potentially difficult protein folding problems to come up with possible solutions. And it seems to be working. More than 100,000 people have downloaded Foldit since its release in 2008, turning the game into a large, worldwide, multiplayer competition.  

Check out the YouTube Foldit video to learn how it works!

Please visit the Foldit site and blog for more information.

Until next time...

Good Luck and Good Protein Folding!!!!!!

 

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Life Sciences Education: The Ongoing Shortage of Qualified Teachers

My oldest son is a high school sophomore and is currently taking “honors” biology. While he is generally an “A” student, it is obvious that he is neither interested in biology nor motivated to perform to his ability in the class. Many of his “A-student friends” are also not doing well in biology class. This gave me pause for concern as a life-long science educator (and certified high school biology teacher). With this as a backdrop, I decided to meet with his teacher to determine why so many good students are underperforming in her class. After meeting with his teacher on two separate occasions, it was readily apparent why so many talented students were performing poorly in her class—she lacks the requisite educational and scientific skills to be an effective biology teacher.  This was confirmed by the head of curriculum development in my school district who told me that the last time that the district had an opening for a high school biology teacher he had two applicants (neither of which had strong biology credentials)—this in the state of New Jersey which is touted to have one of the best public school systems in America.

It is no secret that there is a nationwide dearth of qualified science and math teachers. US officials have been angsting over this problem for about 20 years and have been unable or unwilling to come up with solutions. To that end, I propose the following: induce some of the many currently unemployed life sciences PhDs to consider teaching at the middle and high school levels. While this may sound unorthodox and unappealing to most card-carrying PhDs, there are many benefits to becoming a middle or high school teacher.

  1. Starting salaries for public school teachers with PhDs are very competitive
  2. The school year is only 10 months long and your summers are free
  3. The healthcare and 401 K/pension benefits are better than those in academia and industry (and contributions are usually paid by the school district)
  4. There are guaranteed, negotiated yearly raises and longevity pay
  5. Tenure is awarded after only three years
  6. Curricula requirements and guidelines exists but teachers can run their classes any way that they like
  7. Motivated and innovative teachers are encouraged to create new courses, apply   for grants for curriculum development and sometimes—depending upon facilities—offer students an opportunity to conduct independent research projects
  8. School districts like to hire PhDs because it implies scientific excellence

While there are many benefits to being a teacher, it is not for everybody who holds a PhD degree.  I don’t recommend taking a teaching job (out of desperation) if you don’t like to teach—you, your supervisor and your students will be miserable And, you likely will have frustrated and unhappy parents— like me—visiting your regularly.

We PhDs are enormously invested in the ways that we are perceived by our peers. And, I suspect that the mere mention of teaching high school to your friends, colleagues and supervisors will likely result in surprised looks and lot’s of head shaking. Unfortunately, it is this parochial thinking that has caused America to lose it competitive edge and scientists who chose to teach rather than do research are generally perceived as being less intelligent or competent than their peers. Ironically, it is this close-mindedness and pejorative thinking that has contributed to America’s two-decade long slide in science and technology. Perhaps it is time for PhDs to be part of the solution rather than part of the problem!

Until next time…

Good Luck and Good Job Hunting

P.S. Please contact me if you are interested in teaching biology in the East Windsor Regional School District in New Jersey.

 

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