Everything You Need to Know About Hiring Contractors

While I spend most of my time as a freelancer, I sometimes will do contract work because the pay is good and the hours are reasonable. As many of you know by now, using contractors rather than hiring new employees has become the new way of controlling costs and keeping the full time headcount low. After all, paying someone an hour wage without covering insurance and other employee benefits costs can be huge savings to companies trying to maintain competitiveness and cut costs.

During my various stints as a contract employee, I learned that the rules governing the hiring of contractors vary widely from company to company and agency to agency. Consequently, there are a lot of myths, urban legends and misinformation regarding hiring contractors and the obligations of employers to them. Admittedly, I am a bit confused about the rules surrounding hiring and employing contractors despite the fact that I have been a contractor on more than three occasions. 

For those of you who may be confused as me or others who simply want to learn more about contracting, I highly recommend an article by Katherine Reynolds Lewis in the small business section of the NY Times entitled “Hiring Contractors Without Getting Into Trouble.”

The article offers a comprehensive overview of the Federal laws governing contractor hiring practices, the challenges of a contractor workforce and how to maximize the effectiveness of contract employees. Despite its obvious employer bias, it does paint a realistic view of what persons interested in contract work will likely encounter in the workplace.

Until next time....

Good Luck and Good Job Hunting!!!!!!!!!

 

Regulatory Affairs Update; FDA 483 and Warning Letters Trends for 2012

Those of you who manufacture products approved by the US Food and Drug Administration (FDA) are well aware of the importance of complying with Current Good Manufacturing Practices (cGMP) during FDA mandated inspections of your manufacturing facilities. Failure to comply with cGMP requirements during an inspections results in the issuance of 483s. And if you fail to adequately address the concerns of the agency outlined in 483s, it may ultimately result in issuance of warning letter to your company.

FDA is more vigilant and aggressive than ever before with its 483 and warning letter enforcement procedures. In the words of Commissioner Margaret Hamburg, FDA is quick, visible and vigilant.  With this in mind, it may be worthwhile to participate in a webinar offered by Expert Briefings.com entitled “Top Compliance Trends for 483 and Warning Letters for 2012—Based on Rare FDA Data.”

The webinar will be held on March 8, 2012 from 2:00-3:30 PM EST and Dennis Moore, Managing Partner, AUK Technical Services and a 28 year veteran FDA investigator will lead it. 

Topics to be covered include:

  • Top warning letter trends for 2012, such as more 806 enforcement
  • The Top 10 QS 483 Observations for 2010 and 2011
  • Most common quality system failures for drugs for 2010
  • Top drug and device citations in 483s for 2010
  • Top drug and device warning letter citations for 2010
  • Total 2010 BIMO inspections for CDER, CBER, CDRH, and CVM
  • Details on clinical investigator, sponsor/monitor and IRB audits for 2010
  • Most common sponsor deficiencies for 2010
  • The rising trend of ‘cease to market’ letters, one of which hit a NY pharma company in 2011
  • The total number of 483s issued in 2010 and 2011 – an all time high
  • Total CAPA 483 observations in 2010
  • How long to receive a warning letter, based upon which offices issues it
  • 483 inspection targets for drugs and devices for 2010, 2011, and 2012
  • Total warning letters issued by drug and device category in 2010
  • Which district offices write the most warning letters
  • How long to receive a warning letter, based upon issuing office
  • Warning letters issued by QS system for 2010
  • 483s broken down by QS subsystem for 2010
  • Warning letters by CFR section
  • Top device 483 observations for 2010
  • Details on process validation observations for 2010
  • Design control 483 observations by category for 2010
  • Click here to visit Expertbriefings.com.

Click here to visit Expertbriefings.com.

I hope to see (hear ?) you at the webinar!

 

Emerging Opportunities for US Pharma and Biotech Sales Reps

Since 2001 many major pharmaceutical companies have been restructuring their sales forces and laying off reps to reduce redundancies, improve efficiencies and cut costs. This downsizing, which likely peaked about a year ago, is mainly in response to the projected loss of sales revenue as many blockbuster drugs lose patent protection over the next three years or so. For example, products like Lipitor, Plavix and Zyprexa that currently generate more than $142 billion in sales are expected to face stiff generic competition in the very near future.

Nevertheless, while many pharma companies are restructuring their sales forces, there is a growing demand for new reps at speciality pharma, biotechnology and generic drug companies. Unlike their pharma counterparts, the new reps are more specialized and require additional training to better understand how to maximize sales of increasingly complex products in both developed and emerging life sciences markets.  

One organization, National Association of Pharmaceutical Representatives (NAPRx), a trade organization that provides continuing education, certifications and career development for its members is helping to usher in the era of pharmaceutical and biotechnology sales reps. To that end, NAPRx has embarked on an aggressive advertising campaign to help to recruit and match sales representative with drug companies who are hiring. Many sales jobs are open throughout the US. Jobs are available in small cities like Littlerock, AR, Milwaukee, WI and Baton Rouge, LA as well as larger cities including Pittsburgh, PA, Los Angeles, CA,Boston, MA, Honolulu, HI and San Diego, CA. Starting salaries range from $65 to $85 K. For more information about other job openings please visit the BioJobCenter. 

In a previous blog post, I suggested that a career as a sales rep may represent viable alternate career opportunities for PhD-trained scientists who have an interest in sales and aren’t averse to earning a living selling drugs to physicians and other healthcare providers. Because of the complexity of newly approved biotechnology and speciality pharma products, drug makers are beginning to understand that persons with a strong background in molecular biology, immunology and pharmacology will be required to help to sell their products to physicians, hospitals and other healthcare organizations. That said, sespite the recent reductions in R &D for new drug development, there will always be a need for drug makers to sell their products! After all, selling drugs is how these companies remain in business. 

For more information about a career in pharmaceutical and biotechnology sales please visit the NAPRx website.

Until next time... 

Good Luck and Good Job Hunting!!!!!!!!!!

 

BioJobBlog Surpasses the 2.0 Million Reader Mark!

I started BioJobBlog in 2007 primarily as a means for me to express myself about life science careers and issue and challenges confronting the biotechnology, pharmaceutical and medical devices industry. That said, I never thought that BioJobBlog would ever amount to much; it was simply a vehicle for me to rant and rave about things that were important to me! It is a daunting challenge to begin a blog with no readers and then realize that 5 years later over 2.0 million unique readers have visited to read my thoughts and ideas about a wide breadth of topics.

I want to thank the readers who continue to visit BioJobBlog. And, I hope that what I have written over the past five years has either helped or induced you to think about issues in the life sciences industry. While I have no plans to stop blogging; my schedule is becoming increasingly challenging and I can no longer post articles as frequently as I have in the past. Nevertheless, I will continue do what I can to keep the content at BioJobBlog interesting, fresh and thought-provoking. 

Please feel free to contact me with ideas, thoughts or comments about the blog (or anything else for that matter). 

Thanks for supporting BioJobBlog!

Until next time...

Good Luck and Good Job Hunting!!!!!!!!!

 

Is There Any Wonder Why Big Pharma Has a PR Problem?

Disposing of unused prescription and over the counter drugs including antibiotics, antidepressants, anticonvulsants and birth control pills by dumping them down the toilet has contaminated the drinking water supply for 41 million Americans. Further, unused prescription drugs stockpiled in medicine cabinets can contribute to drug abuse or overdoses by children, teens and adults. Currently, there are no guidelines or regulations in place to deal with the safe disposal of unused consumer medicines and drugs.

According to a post on today’s Pharmalot blog, a Washington State senator is introducing legislation (for the fourth time) to develop an environmental safe plan to dispose of unused and potentially harmful medications. The plan calls for dropping off unused medicines at local pharmacies; a service that would be underwritten by the pharmaceutical companies who manufacture the drugs. And, wouldn’t you know it, PhRMA, the pharmaceutical industry trade groups is lobbying and fighting against the legislation for the fourth time. In addition to PhRMA, the Consumer Health Products Associations which represents manufacturers of over-the-counter drug and the Washington Biotechnology and Biomedical Association are fighting the proposed legislation. Some municipalities like the City of Puyallup, WA allow persons to dispose of prescription medications including cancer treatments, painkillers, antidepressants and statins in lock boxes in the hallway of the local police department. However, these municipalities are the exception not the norm.

The groups opposing the legislation contend that regulations are unnecessary because contaminating drugs found in drinking water results not from improper disposal practices but through urination and defecation. In fact, they contend that the best way to dispose of unused medicines is in the household trash. But what about leeching of these drugs from landfills into aquifers and other sources of drinking water you ask? And what about dealing with potential drug abuse and sale of illegal prescription drugs? 

Interestingly, I had some minor surgery last week that required some pain medication and as I was rummaging through my medicine cabinet, I found a at least eight bottles of pain medication prescribed for various family members dating back to 1999. I thought about getting rid of the expired pills, but I had no idea about what the best disposal method may be. Consequently, the pill collection is still taking up space in my medicine cabinet. And, with two teenagers in the house, I am starting to get a little anxious! 

That said, it makes perfect sense to me that there ought to be regulations guiding the disposal of drugs in the US. And, because drug manufacturers have made huge profits on their products, I see no reason why drugmakers should not support and help to underwrite programs to safely dispose of unused prescription and over-the-counter medications. Maybe people’s negative impression of big pharma would improve if the powers at be would just suck it up for once and pay to help to solve problems that helped to create!

Until next time...

Good Luck and Good Job Hunting!!!!!!!!

 

More Biotech Downsizing

Cambridge, MA-based Alnylam Pharmaceuticals, one of the many companies founded on the promise of RNAi technology today announced that it will reduce its current workforce by 33 percent to focus its financial resources on its leading RNAi treatment for hemophilia. Alnylam currently employs 173 persons which means that about 59 employees will lose their jobs as the company reorganizes itself.

Alnylam CEO, John Maraganore, PhD hopes that the downsizing and reorganization of the company will result in a $20 million savings for fiscal year 2012. Despite the hype, RNAi is still not ready for prime time as commercializable products and will likely be little more than an R&D tool.

Until next time...

Good Luck and Good Job Hunting!!!!!!!!!!

 

BioJobBlogger Revealed

Ome Ogbru, Pharm. D, CEO and Founder of Rxeconsult, a new networking site for healthcare consulting and jobs, asked me if I would be interested in being interviewed about the companies and websites that I started.  Of course I could not refuse.  So here goes:

 

RxEconsult: What is BioInsights and why did you develop BioInsights?

BioJobBlogger:  BioInsights founded in 1998 was originally a bioscience training and education company.  The goal of the company was to help life scientists get the training that they need to get jobs at life sciences companies. Today, BioInsights, Inc is more of a career development company that provides individualized career development guidance and counseling for life scientists. This is because the life sciences job market has changed considerably since 1998 and jobs are harder to come by. However, we still offer bioscience training in drug development, regulatory affairs and biomanufacturing. Additionally, BioInsights also offer medical communications consulting services.

RxEconsult: How do you distinguish BioInsights from other Medical Communications companies? 

BioJobBlogger: Unlike traditional medical communications companies, BioInsights offers writing services that heavily focus on social media platforms like LinkedIn, Twitter and various blogging platforms.  We also offer medical writing, copywriter and website content development services.

RxEconsult: What are the main challenges in your business and how are you addressing them?

BioJobBlogger: Training and career development services are not high priorities for job candidates or life sciences companies until a scientist is looking for a job or a company needs to hire new employees.  Consequently, it is difficult to convince both companies and jobseekers to be proactive and engage us early in the process. We are beginning to address this problem by turning to various social media platforms to get the word out about our services. Paradoxically, the recent economic downturn has been good for our business activities!

RxEconsult: What attracted you to social media and blogging? How can professionals make a living or develop their career by blogging?

BioJobBlogger:  I enjoy writing and always have had a strong desire to share my ideas and opinions with others. Blogging seemed like a natural extension of what I like to do. So, about 6 years ago I launched BioJobBlog (www.biojobblog.com) which is focused on life sciences career development topics as well as opinion pieces and reports on the goings on in the life sciences industry. While blogging is exciting and extremely cathartic, it is difficult to make a living as a blogger. The days of individual bloggers selling their blogs for millions to large media outlets are over.   That said, blogging is useful in establishing yourself as a subject matter expert which can sometimes lead to paid opportunities.  At its peak last year, I was averaging between 65,000-70,000 unique visitors per month @ BioJobBlog.

I built traffic to the levels I mentioned by blogging 4-5 times per day and staying abreast of late breaking events in the life sciences industry.  I was able to maintain that pace for a couple of years but because I blog for free, I could not sustain the pace any longer. The original goal was to reach 100,000 unique visitors per month and then try to sell the blog or form an alliance with a media outlet. Obviously, that did not happen.  I am now happy to log between 30,000-45,000 unique visitors per month by blogging three times per week or whenever the urge strikes me.

As far as revenue is concerned, it has not been much.  It costs me about $2400 per year in hosting and management fees and I have been blogging for over 5 years.  In that timespan, I may have made several thousand dollars but not enough to break even or turn a profit.  Blogging is truly a personal medium that is driven more by desire and the need to be heard rather than a profitable enterprise; unless of course you can get a major media outlet and blog for them.  That is really my dream job right now!

RxEconsult: What are the top social media practices that professionals should use for developing their career?

BioJobBlogger: I think that LinkedIn, Twitter and a personal blog can really help in terms of career development for life scientists.  However, all of these platforms require daily monitoring and care. Sadly, most life sciences professional spend most of their time in the laboratory and fail to realize that career development is vital and cannot be ignored if one wants to find a job!

RxEconsult: What healthcare gaps can social media address? 

BioJobBlogger:  I believe that social media can be used in real time for adverse event reporting and educational outreach activities. Unfortunately, most drug makers view social media as means to bolster sales or look for specialized employees.  That said, these are early days for life sciences companies and social media and it will interesting to see how social media evolves in the life sciences industry.

RxEconsult: Why are biopharmaceutical companies struggling with leveraging social media and how can they best use social media? How can BioInsights help them?

BioJobBlogger:  The life sciences industry is very conservative and adverse to change.  Social media is clearly a game changing phenomenon and most life sciences companies don’t know what to make of it yet.  Over the past three years or so, more and more life sciences companies have experimented with various social media platforms and are beginning to realize their potential for their businesses.  

BioInsights can help companies navigate the social media jungle because of our experience using social media platforms and also developing life sciences websites and blog content.

RxEconsult: What feedback have you received and how are your websites performing?

BioJobBlogger: I recently redesigned the BioInsights website and traffic has been down. Most of my focus is on two other BioInsights web assets---BioJobBlog and BioCrowd (www.biocrowd.com) an online networking community for bioprofessionals.  

I frequently get comments @BioJobBlog about its content and how helpful it is to jobseekers and other bioprofessionals. BioCrowd was launched about three years ago and we are still growing the community. At present, joining BioCrowd is primarily through invitation only.  We are embarking on a mass membership drive early next spring.  At present there are 4,200 BioCrowd members.

RxEconsult: If you wrote a book about how to develop and run a business what pearls would you include?

BioJobBlogger: No matter how good the idea is, it is all about marketing! Good ideas with insufficient marketing power can easily fail whereas bad ideas with mega-advertising can succeed.  As a scientist myself, I failed to realize how important marketing and advertising are! In hindsight, I would have invested much more money and effort in marketing my business rather developing content and building sleek looking websites!

RxEconsult:BioJobBlogger, thank you for sharing your views and discussing your ventures. Hopefully, you can return to give us an update. I wish you success and I hope you find that dream job!

 To comment on this article or ask questions  join the RxEconsult community, a free business network for healthcare consulting, jobs, and more.

 

Asian Pharmaceutical Giant Takeda To Eliminate 2,800 Jobs in the US and Europe

Asia’s largest drug maker, Takeda, today announced that it will eliminate 2,800 jobs or about 9% of its workforce in the US and Europe. The job cuts, planned over the next four years, are intended to better integrate NycoMed, the Swiss company purchased by Takeda for $12 billion last September.

Most of the positions affected by the downsizing are in the US and Europe and will help the company save $1.7 billion over the next year or so.The plan includes the elimination of 2,100 jobs mainly in Europe and 700 in the U.S. across research, commercial, operations and administrative functions. Takeda currently has about 30,000 employees worldwide with operations in 42 countries.

The reason for the downsizing is slumping US sales of the company’s top selling drug Actos (diabetes) that will lose patent protection this August and face stiff generic competition. Like other pharmaceutical companies, Takeda is abandoning the US and European markets in favor emerging markets in China, India, Brazil and the Middle East.

Until next time...

Good Luck and Good Job Hunting!!!!!!!!!

 

Last Call for BDI's Mobile Healthcare Conference

 

For additional information, including registration, please click here to visit the event website. Use promo code BC for a discounted rate of $175.

Date: Thursday, January 26, 2012
Time: 8:00 a.m. - 1:00 p.m.
Place: The Graduate Center of The City University of NY; 365 5th Ave; NY, NY 10016
Registration Fee: $195.00
Website: http://www.bdionline.com/mobilehealthcare2012.html


Representatives from the following companies are currently registered to attend: Affect Strategies; Alembic Health Communications; Allergan; Anderson Direct Marketing; Aurora Information Technology, Inc.; Baldwin Publishing; BlippMedia; Bristol-Myers Squibb Company; Brodeur Partners; Care Innovations; Cinchcast; CMI/Compas; ConferencePlus; Daiichi-Sankyo; DKI; Draftfcb Healthcare; DraftFCB/NeON; Edelman; eurorscg; Eveo; FreeMind; GCI Health; Google; Hale Advisors Inc.; hamad medical corporation; Huntington Hospital; HY Connect; IMC2 Health and Wellness; International Association of Business Communicators; Kwittken + Company; Makovsky & Co; Manhattan Research; Mom Central Consulting; Mount Sinai Hospital; MultiVu; NNN; Ogilvy; Padilla Speer Beardsley; Pharma Marketing News / Pharma Marketing Blog; Physicians Interactive; Pixels & Pills; Porter Novelli; PR Newswire; PRN Communications Inc; Public Relations Society of America - New York Chapter; SAY Media; Shire; State University of New York Buffalo; Stephanie Grayson; ToGoRun; Trident Communications; Turning Point Solutions, Inc.; United Healthcare; Velocidi; Wake Forest Baptist Health; WCG; Wharton, University of Pennsylvania; Within3; Yankee Public Relations; and others.

Attendee Testimonials:
Click here to see what our past attendees are saying about us.


About the Event:

Consumers and professionals are increasingly using their mobile devices for healthcare information. They are also interacting with healthcare providers and colleagues on their mobile phones. This conference will demonstrate the best case studies of how major healthcare brands are connecting with consumers and professionals through mobile communications. 

Agenda:

 

8:00 a.m. - 8:30 a.m.

Registration & Networking Breakfast 

8:30 a.m. - 8:40 a.m.

Introductory Comments
Steve Etzler, Founder and CEO, Business Development Institute 

8:40 a.m. - 8:50 a.m.

Introductory Comments
PR Newswire 

8:50 a.m. - 9:15 a.m.

Case Study:  Multiscreen Health 2012 
Presented by: Monique Levy, Vice President, Research, Manhattan Research
Smartphone and tablet adoption jumped significantly between 2010 and 2011. How are consumers and HCPs using multiple screens for health and how can marketers keep pace with this rapidly changing environment? Manhattan Research Vice President Research Monique Levy will discuss key trends from the Taking the Pulse® U.S. and Cybercitizen Health® U.S. studies.

9:15 a.m. - 9:40 a.m.

Case Study: Text in the City
Presented by: Dr. Katherine Malbon, Assistant Professor of Pediatrics, Division of Adolescent Medicine, Mount Sinai Hospital 

Lessons learned from a pilot text messaging program connecting adolescents to their 'health home'. Katie Malbon will discuss her pilot text messaging program that she initiated in a large adolescent health center. She will illustrate the feasibility of the program and how it laid the ground work for other SMS-based programs within the center and beyond.

9:40 a.m. - 10:05 a.m.

Case Study: Successfully Collaborating with Healthcare Professionals through Online Community Programs: A Case Study Approach
Presented by: Peter Gannon, Regional Vice President, Within3 

Fostering collaboration and engagement is everyone's goal in HCP communications. Enabling technologies that accomplish these goals in a regulated environment can be challenging given perceived constraints from legal, regulatory, medical, and compliance. Peter will introduce some successful cases on how the implementation of private secure HCP networks have enabled greater HCP collaboration, increased the quality of HCP relationships, realized cost savings, and were implemented in accordance with company risk mitigation policies.

10:05 a.m. - 10:25 a.m.

Break

10:25 a.m. - 10:35 a.m.

Introductory Comments
Rob Drasin, President, International Association of Business Communicators New York & President, Trident Communications

10:35 a.m. - 11:00 a.m.

Case Study: The Power of Integrating Mobile into the Marketing Mix
Presented by: Jenna Mons, Consumer Product Manager for LAP-BAND®, Allergan 

An overview of the importance mobile can play as a key channel to reach and interact with customers. Looking specifically at how LAP-BAND created a mobile footprint in the 2011 to attract new customers and increase conversion.

11:00 a.m. - 11:25 a.m.

Case Study:
Presented by: John Vieira, Daiichi-Sankyo

11:25 a.m. - 11:50 a.m.

Case Study TBD

11:50 a.m. - 12:00 p.m.

Break

12:00 p.m. - 12:30 p.m.

Roundtable Session 1

12:30 p.m. - 1:00 p.m.

Roundtable Session 2

 

Roundtable Moderators:
Meighan Berberich, Vice President, Marketing, Cinchcast
James Chase, Editor-in-Chief, Medical Marketing & Media
George DeTorres, Divisional Vice President - Business Development, MultiVu
Rob Drasin, President, International Association of Business Communicators New York & President, Trident Communications
Sandra Fathi, President, Public Relations Society of America - New York Chapter & President and Founder, Affect 
Peter Gannon, Regional Vice President, Within3

Scott Hopkins, Executive Vice President, Anderson Direct Marketing
Theresa Jacobellis, Director of Public Affairs, Huntington Hospital 
Monique Levy, Vice President, Research, Manhattan Research

John Mack, Editor and Publisher, Pharma Marketing News / Pharma Marketing Blog 
Dr. Katherine Malbon, Assistant Professor of Pediatrics, Division of Adolescent Medicine, Mount Sinai Hospital
Talya Miron-Shatz, PhD, Marketing Department, Wharton, University of Pennsylvania 
Jenna Mons, Consumer Product Manager for LAP-BAND®, Allergan 
Mario Nacinovich, Jr., Editor-in-Chief, Journal of Communication in Healthcare
Managing Director, AXON
Xavier Petit, Shire

Hotel Sponsor: Hotel 373 is the official hotel of BDI's events.

Sponsors:
PR Newswire / MultiVu; Within3; Anderson Direct Marketing; BioCrowd; Cinchcast; FierceMarkets; International Association of Business Communicators - New York Chapter; Journal of Communication in Healthcare; Manhattan Research; Mobile Marketing & Media; New York American Marketing Association; New York University; Pharma Marketing News; Pixels and Pills; Public Relations Society of America - New York Chapter; Sales Lead Management Association; Society for Healthcare Strategy and Market Development

For event related questions and registration, please contact Maria Feola-Magro at mfeola@bdionline.com or 212.765.8043.
For sponsorship/speaking opportunities, including pricing, please click here or contact Jennifer Brous at jbrous@bdionline.com or 212-765-8358

For additional information, including registration, please click here to visit the event website. Use promo code BC for a discounted rate of $175.

 

About BDI:
Business Development Institute (BDI), founded in New York City by Steve Etzler in 2001 and managed by Maria Feola, produces conferences and educational programs for marketing, communications and media professionals. Over 11,000 attendees have participated in our programs. We specialize in how technology and the internet impacts marketing, communications and media. Our programs educate while providing valuable networking opportunities to our attendees. The quality of our speakers, program topics, 1/2 day format, network, and value are what differentiates BDI from its competitors. Follow us on Twitter at www.twitter.com/bdionline. For additional information as well as sponsorship information, please download our Media Kit.

 

What we have done lately in the Healthcare industry:

11/10/2011 Healthcare Social Communications Leadership Forum

07/13/2011 Social Communications & Healthcare 2011: Case Studies & Roundtables

06/09/2011 Healthcare & Life Sciences Social Communications Leadership Forum

03/17/2011 Healthcare Social Communications Leadership Forum

01/19/2011 Mobile Healthcare Communications: Case Studies and Roundtables

 

Oops...Novartis Does It Again!

Earlier this week, I suggested in a post that pharma layoffs were beginning to decline whereas biotech layoffs were rising. And wouldn’t you know it, just when big pharma employees thought that their jobs were safe, the Swiss pharmaceutical giant Novartis today announced that it was laying off 2,000 US employees. According to a post on the Pharmalot blog, 1,630 sales reps and an additional 300 positions will be eliminated at Novartis’ Hanover, NJ US headquarters. Last fall, Novartis eliminated 1,100 jobs in Switzerland, 900 R&D and 1,400 sales reps in The US and another 550 jobs at a manufacturing site in the UK 

While the announced layoffs may be part of a global downsizing effort that began last year, many analysts believe Novartis decided to reorganize because its new hypertension drug, Tekturna, performed poorly in clinical trials (increased incidence of non-fatal stroke, renal complications, hyperkalemia and hypotension) to garner approval of the drug to treat patients with Type II diabetes who are a greater risk of cardiovascular and renal events. The company’s best-selling hypertension medicine Diovan lost patent protection in Europe earlier this year and it due to expire in the US next September.

Company executives were betting on Tekturna to replace hypertension sales lost to generic competition for Diovan. Tekturna, approved in Europe as Rasilez, generated sales of $449 million during the first nine months of the past fiscal year but the poor clinical trials results suggest that it may be difficult for the drug to generate the $1.4 billion in annual sales (by 2016) forecasted by many financial analysts.

Stay tuned for more big pharma layoff updates!

Until next time...

Good Luck and Good Job Hunting!!!!!!

 

Canada Continues to Shed Biotech Jobs

Yesterday I reported that Cangene, one of Canada’s oldest and largest biotechnology companies was reorganizing and laying off 120 employees. Today, the French drug maker Sanofi-Aventis announced that it would eliminate 100 jobs at its Montreal area (Laval) facility to allow for better integration of Genzyme, the Massachusetts-based biotechnology company that was acquired last year for more than $20 billion. About 1,700 employees work for Sanofi’s Canadian division.

Today’s layoff news comes only day after Johnson & Johnson announced that it would close its Montreal research center and layoff 126 employees. This is bad news for Montreal which emerged as one of Canada’s hot pharmaceutical and biotechnology zone in the early 2000s. 

The Canadian biotechnology sector is much smaller than its US counterpart but there are several high profile companies that have been able to establish themselves as players in the global biotechnology industry. Hopefully, these companies will be able to weather to the economically-challenging times that are currently plaguing the Canadian biotechnology industry.

Until next time...

Good Luck and Good Job Hunting!!!!!!!!!

 

Are There Career Opportunities in Stem Cell Research?

Stem Cell research was hot in the early 2000s. Sadly, 8 years of George Bush effectively eliminated America's competitive edge in the field, primarily in embryonic stem cell research.  Consequently, it is no surprise that there is little emphasis or discussion about stem cell research in the US.  To that end, a recent Gallup Poll was conducted to determine American attitudes and perceptions of stem cell research.  The results of the poll (originally posted the the Assay Depot blog) are shown below.

The poll results suggest that over 50% of Americans surveyed believe that all forms of stem cell research are morally acceptable.  Interestingly, while increasing number of American believe that stem cell research should progress, government funding for it has markedly declined since 2009 even though the ban on embryonic stem cell research was removed.

The take home message is that Bush's 8 year band on embryonic stem cell research has seriously affected American competitiveness in the field and that it is no longer a priority of the US government.  The bottom line: I would not plan a career in stem cell research unless you are willing to relocate outside of the US.

Until next time....

Good Luck and Good Job Hunting!!!!!!!!!

 

Pharma Layoffs Decline As Biotech Layoffs Rise

This past holiday season, as usual, was rife with massive layoffs and downsizing at various big pharma companies. Interestingly, in 2011, most biotechnology companies were able to weather the economic downturn and layoffs were not typical. Sadly, 2012 looks to be a more challenging year for many biotechnology company employees.

In the past week or so, several relatively high profile public biotechnology companies announced layoffs. First, on January 5, XOMA, the long- struggling California-based biotechnology company issued a press release indicating its intention to reorganize to focus it financial resources on its lead product gevokizumab and the company’s unique antibody discovery and development capabilities. The reorganization will result in elimination of 84 positions (34% of its workforce) with 50 jobs being lost immediately and the remainder by the end of the first quarter of this year. The layoffs will save the company $14 million. The same day, Winnipeg-based Cangene Corp, one of Canada’s oldest and largest biotechnology company announced that it would eliminate 120 jobs or 17% of its current workforce.  Finally, today, Human Genome Sciences (HGS) announced at the annual JP Morgan conference in San Francisco announced plans to eliminate 150 jobs across multiple departments.

The HGS announcement was somewhat surprising because the company recently received approval for a pioneering systemic lupus erythematous drug called Benlysta. Apparently, poor Benlysta sales have battered the company’s stock price which resulted in the announced layoffs. HGS reported Benlysta sales of a slightly more than $25 million in the fourth quarter which were must less than analysts had originally predicted.

Although these layoffs may be troubling to some, it is important to note that each of  the three companies have been in existence for 20 years or more and are transitioning from research organizations into companies that are finally commercializing their products. Like it or not, companies with commercial products are held to higher standards and receive much greater scrutiny than start ups and early stage companies. That said, while there may be additional layoffs at some older more established biotechnology companies, it may be a good time to start a company. Word on the street suggests that there is a lot of investment capital out there for new start ups!

Until next time...

Good Luck and Good Job Hunting!!!!!!!!!!

 

Mirror, Mirror On the Wall: Which Recent College Graduates Have the Highest Unemployment Rates of All?

It is no secret that recent college graduates are having a tough time finding work. However, not all college majors are created equal and the unemployment rates among different disciplines are likely to vary. To answer this question, a group of researchers at the Georgetown Center on Education and Workforce analyzed employment data for recent college graduates from an in-depth US census study entitled the American Community Survey conducted in 2009 and 2010. In the study, recent college grades were defined as workers (with college degrees of course) between ages 22 and 26.

The results of the study are shown in the graph below.

The data clearly show that among recent college grads, those who studied architecture have the highest unemployment rate at 13.9%. This finding was not that surprisingly given that the collapse of the housing and construction markets were mainly responsible for the ongoing recession that began in 2007. 

Unemployment rates were lowest among college graduates with training in education and healthcare. Again, these results are not that start. Again, these results were not startling because the US population continues to age (healthcare-related jobs) and the number of school-aged children skyrocketed in the past 20 years (education jobs).

Interestingly, the unemployment rate among engineering graduate, 7.4% is relatively high despite the fact that HR and employment experts contend that there is a shortage of engineers in the US.

Finally, unemployment rates among graduates with art degrees and those who possess degrees in the humanities and liberal art are still very high at 11.1% and 9.4% respectively. That said, maybe getting that MS or PhD degree in the life sciences was not such a bad idea after all!

Until next time...

Good Luck and Good Job Hunting!!!!!!!!!!!

 

Preparing For and Coping With Annual Performance Reviews

For many corporate employees, the annual performance review process is a bane to their existence. For those of you who may not be familiar with annual reviews, most corporate employees are required to undergo a review process that includes a synopsis of their accomplishments over the past year and new goals for the upcoming one. And, as all corporate employees understand, the quality of an annual review determines the size of the bonus that they can expect to receive and whether or not a salary increase is in order for the upcoming fiscal year. In other words, you never want to get a “less than stellar” annual review because your fiscal well-being depends on it!

Not surprisingly, preparing for the annual review can be nerve-racking and dealing with the results of the review can be equally challenge (especially if the review is a negative one). Although, most of the annual reviews for 2011 have been completed, Eilene Zimmerman who writes the Career Couch for the New Times posted a helpful article that deals with preparing for the dreaded annual review and how best to respond to either a positive or negative one.

I can tell you from personal experience, the annual review is probably one of the silliest and most inane things that was ever invented for corporate employees. That said, it is part and parcel of the corporate workplace game and to excel you need to get good at!

Until next time...

Good Luck and Good Job Hunting

 

And The Worst Biotech CEO of 2011 Is......

Annually, the Street.Com surveys its readers to identify the year’s worst biotechnology CEO. Yes, despite large salaries, great benefits and, in most cases, outstanding employees, the executives who make the list just can't seem to do the job right.

The 2011 survey was just released and this year’s five worst CEOs are: 

  1. Mitch Gold—Dendreon Corp
  2. Greg Divis, Jr—KV Pharma
  3. Al Mann—Mannkind Corp
  4. Joe Zakrzewski—Amarin Corp
  5. John Martin—Gilead Life Sciences

Other notable nominees included: Elan Pharmaceutical’s Kelly Martin, Genzyme’s Henri Termeer and Dan Bradbury of Amylin Pharmaceuticals.

Honorable mention awards went to Jim Bianco of Cell Therapeutics, Doug MacLellan of Radient Pharmaceuticals and Brian Culley of Adventrx Pharmaceuticals.

Despite these dubious distinctions, I would like to be earning their annual salaries and bonus compensation packages!

Until next time...

Good Luck and Good Job Hunting (I would avoid the companies whose CEOs made the list)

 

Tips on How To Cope After Being Layed Off

Getting layed off is not uncommon in today's economy.  Nevertheless, it is a difficult experience even for the most season employees.  I found a video on YouTube that provides some ideas on how to manage being layed off and what you can do to get back up on your feet. 

Until next time...

Good Luck and Good Job Hunting!!!!!!!!!

Astra Zeneca Will Layoff 1,150 Sales Reps

Last week, US unemployment dipped to 8.6%, it lowest level since 2008. Stock markets rose and everyone was buoyed by a possible economic recovery. What a difference one week can make. Today, Astra Zeneca announced that it will layoff 1,150 sales reps; a few short weeks after announcing plans to eliminate 400 jobs at is US headquarters in Wilmington, DE. The company currently employs about 61,000 workers worldwide, including 14, 000 in North America.

According to the president of Astra Zeneca US, today’s announcement is part of the larger layoff of 10, 400 employees announced back in 2010. These layoffs are largely the result of loss of patent protection for several of Astra Zeneca’s largest selling drugs including Crestor (cholesterol), Nexium (acid reflux) and Sereoquel (anti-pyschotic).  Today’s announcement brings the total of US pharmaceutical employees who lost their jobs this year to about 20,000 according to a post on the Pharmalot blog.

Tis the season, after all!

Until next time...

Good Luck and Good Job Hunting!!!!!!!

 

Ten Female Biotech Executives to Watch in 2012

Fierce Biotech conducted its annual survey to identify top female executives in the biotechnology industry. After receiving 130 nominations, they compiled a Top 10 List for 2011.  While some notable women executives may not have made it onto the 2011list, there is always next year.

Their list is as follows:

  1. Katrine Bosley—CEO, Avila Therapeutics
  2. Susan Desmond-Hellman, MD—Chancellor of USCF (formerly @ Genentech)
  3. Deborah Dunsire,MD—President and CEO, Millennium, the Takeda Oncology Company
  4. Carol Gallagher—CEO, Calistoga Pharmaceuticals
  5. Melinda Gates—Co-Founder and Co-Chair, Bill and Melinda Gates Foundation
  6. Maxine Gowen, PhD, MBA—President and CEO, Trevna
  7. Rachel King—CEO, GlycoMimetics
  8. Tina Nova, PhD—CEO Genoptix Medical Laboratory
  9. Gail Schulze—CEO& Executive Chair of the Board, Zosano
  10. Daphne Zohar—Pure Tech Ventures

If you think that someone who is not on the list deserves to be there, add a comment to this post.

Congrats to the women who made the list!

Until next time...

Good Luck and Good Job Hunting!!!!!!!

 

Looking for a Chemistry Job? This Webinar May Help

I received a heads-up from the American Chemical Society’s (ACS) Sergio Lewis about a free webinar entitled “How to Secure and Nurture a Vibrant Chemistry Career in the 21st Century.” The webinar is scheduled for December 1, 2011 from 2:00-3:00 PM and will be led by Brian Fahie, PhD from Eli Lilly & Co. The presentation will be followed by a Q&A session.

For more information you can download the program here. To register follow this link.

Until next time...

Good Luck and Good Job Hunting!!!!!!!!!!!

 

Tis the Season: How to Ask for a Raise Without Getting Fired!

While many of you are happy just because you have a job, there are those individuals (deserving or not) who are going to “bite the bullet” and ask for a raise. This makes sense because over the past few years the cost of health insurance has gone up along with college tuition, gasoline price and a variety of other things while salaries have all but stagnated. Interestingly, only 9 percent of companies have put pay freezes in place over the past 18 months; a rate this is consistent with historical standards. That is down from the nearly two-thirds of companies that imposed pay freezes in January 2010. In other words, now may be a good time to ask for a raise as companies are trying to retain high value employees who presumably were too vital to lay off when companies were downsizing over the past three years. Sadly, merit raises (when they are meted out) have precipitously dropped in recent years from an average of roughly 4-5 percent to a paltry 2 percent on average today.

Whether or not economic times are good or bad, it is hard for most employees to “ask for a raise.” This is because it is difficult for employees to determine if they are ‘worthy” of a raise. To that end, there was a fantastic article in the NY Times business section last week helps employees determine whether or not they are deserving of a raise and it also provides a road map to actually prepare and ultimately ask for a raise.

It is a great read and provides great insights and ideas for those willing to risk asking their bosses for raises in difficult economic times.

Until next time...

Good Luck and Good Job Hunting!!!!!!!

 

Despite Near-Record Recalls, the Price of Prescription Drugs Continues to Rise

Ed Silverman, the intrepid author of the Pharmalot Blog, reported today that the average price of prescription drugs through last month rose 7.2 per cent; which tops the annual price rate increases over the past decade. The cost analysis was done on 130 prescription drugs.

The biggest winners were: Suboxone, marketed by Reckitt Benckiser to treat opioid addiction which rose 21 percent. Cephalon raised the price of its Provigil narcolepsy pill by 15 percent and Sunovion Pharma hiked the prices of its Xopenex asthma and COPD med by 9.8 percent. Other drugmakers on the list included Genentech, Merck and Abbott Laboratories.

Ed cautioned that “the price changes are based on WAC, or wholesale acquisition cost, for more than 90 percent of the drugs, which means that less than 10 percent of increases are based on direct price or suggested wholesale price” Nevertheless, any wholesale price increases are always passed on to the end users aka patients!

It is troubling that in these tough economic times that drug prices continue to rise at unprecedented rates. And access to reasonably priced medicines continues to diminish.  Not surprisingly, prices continue to rise in advance of healthcare reform legislation that doesn’t kick in entirely until 2014.

Until next time

Good Luck and Good Job Hunting!!!!!!!

 

Some Good News: Allergan Will Open A R&D Facility in New Jersey

The New Jersey Governors Office announced today that the healthcare company Allergan, Inc, known mainly for its eye care products, plans on opening an R&D facility in NJ that will inject $12 million in private investment into the state’s beleaguered economy and add several hundred jobs over the next three to five years. Allergan currently employs about 10,000 people worldwide. Allergan chose New Jersey after it received a $17 million grant from the state to build the facility.  At present its size and location is yet to be determined.

While New Jersey Governor Chris Christie (possibly a vice president candidate) is taking as much credit as possible for Allergan’s decision to open an R&D facility and create jobs, it may be too little to late for New Jersey—home to most of the world’s largest pharmaceutical companies—which has lost tens of thousands of life sciences jobs because of mergers, reorganizations and layoffs.

Nice try Chris but you will have to do better than several hundred new jobs before you can claim that you are solely responsible for New Jersey’s economic recovery. I hope he is selected as a Vice Presidential candidate; then New Jersey will have a chance to right itself after the damage that Christie caused in his first two years as governor.

Until next time...

Good Luck and Good Job Hunting!!!!!!!!

 

In Case You Were Wondering: FDA Approved 35 New Prescription Medicines This Year

Last week, the US Food and Drug Administration issued a press release lauding its approval of 35 new prescription medications in FY2001. According to the release 2011 was a banner year for drug approvals; being only surpassed in FY2009 when 37 new medicines garnered regulatory approval.

FDA detailed its accomplishments in a report entitled “FY2011, Innovative Drug Approvals” which touted faster approval times in the United States as compared with the FDA’s counterparts around the globe. Twenty-four of the 35 approvals occurred in the United States before any other country in the world and also before the European Union, continuing a trend of the United States leading the world in first approval of new medicines. 

Among this year’s highlights:

  1. Two of the drugs – one for melanoma and one for lung cancer – are breakthroughs in personalized medicine. Each was approved with a diagnostic test that helps identify patients for whom the drug is most likely to bring benefits;
  2. Seven of the new medicines provide major advances in cancer treatment;
  3. Almost half of the drugs were judged to be significant therapeutic advances over existing therapies for heart attack, stroke and kidney transplant rejection;
  4. Ten are for rare or “orphan” diseases, which frequently lack any therapy because of the small number of patients with the condition, such as a treatment for hereditary angioedema;
  5. Almost half (16) were approved under “priority review,” in which the FDA has a six month goal to complete its review for safety and effectiveness;
  6. Two-thirds of the new approvals were completed in a single review cycle, meaning sufficient evidence was provided by the manufacturer so that the FDA could move the application through the review process without requesting major new information;
  7. Three were approved using “accelerated approval,” a program under which the FDA approves safe and effective medically important new drugs quickly, and relies on subsequent post-market studies to confirm clinical benefit. For example, Corifact, the first treatment approved for a rare blood clotting disorder, was approved under this program
  8. Thirty-four of 35 were approved on or before the review time targets agreed to with industry under The Prescription Drug User Fee Act  (PDUFA), including three cancer drugs that FDA approved in less than six months.

PDUFA was established by Congress in 1992 to ensure that the FDA had the necessary resources for the safe and timely review of new drugs and for increased drug safety efforts. The current legislative authority for PDUFA expires on Sept. 30, 2012. 

Maybe the agency can keep its streak alive before  PDUFA expires next year!

Until next time...

Good Luck and Good Job Hunting!!!!!

 

Statistics and Job-Related Facts You Should Know About Careers in the Life Sciences

Fewer and fewer American college students are choosing to major in Science Technology, Engineering and Math (STEM). This has been an ongoing trend in the US for the past two decades. However, within the STEM majors, the life sciences are faring the best. While I believe that the US needs more life sciences majors to remain competitive with the rest of the world, there are a few things you ought to know before you take the life sciences plunge.

  1. More than 86,000 American biology majors graduate each year
  2. About 58% of all bachelors’, masters and doctorates in the life sciences are awarded to women (who continue to earn substantially less than their male counterparts)
  3. Entry level salaries for biology majors range from $40,000 to $50,000 per year (computer and engineering students start at salaries of $55,000 to $65,000 per year)
  4. PhD degrees in the life sciences take on average six years to complete
  5. Postdoc starting salaries range from $37,000 to $40,000 per year
  6. More than a third of biologists are still working as postdocs or in other non-tenure track jobs six years after receiving their PhD degrees
  7. Only 14% of PhD-trained biologists win tenure track positions within six years of receiving their degrees
  8. Because of tighter funding for government jobs and the loss of 300,000 pharmaceutical jobs in the past decade, many newly-minted PhDs are forced to become serial postdocs (supported by soft money) or help senior scientists set up and run their laboratories waiting to see if they can win permanent academic employment
  9. Fewer tenured life sciences professors are retiring because of the financial downturn

If you still want to be biology major after reading this post, then I think that you know what career path you ought to pursue! Just sayin’......

Until next time...

Good Luck and Good Job Hunting!!!!!!

 

Want Up-to-Date Pharma News Coverage? Check Out These Blogs

Over the past five years or so there has been a proliferation of blogs that cover the life sciences industry. While I visit some of them frequently, e.g., Pharmalot, EyeonFDA and PharmaLive,.

I am sure that there are others out there that may be useful. To that end, I came across a blog post on the Health and Life website that listed the top 10 essential pharma news blogs. 

#1 Pharmalot

How can we describe the value Pharmalot provides?

Visiting Pharmalot is something we do daily – we can give no blog or resource a higher compliment.  Ed Silverman has the experience to cut through the news and provide readers with the most important tidbits along with pertinent thoughts.

And for those interested in Pharma, the daily email can be quite valuable.

#2 PharmaGossip

Pharmagossip is recognized for horribly accurate, sharp and incisive analysis.  You can feel the author’s passion and concern for upholding ethical standards in almost any post.

Just don’t read before going to sleep or before discussions on whether man is inherently good or bad.

Pharmagossip is a blog that can change how you think about things while keeping up with important pharma news.

#3 In the Pipeline

What’s wrong with dioxygen difluoride and how accurate are HER2 receptor tests?

Derek Lowe does an excellent job of analyzing drugs, especially those that are in the pipeline and being developed.  He’s the kind of guy who points out flaws in a medication a month before clinical trials reveal it’s a dud.

You can wait for the news to be public knowledge.  Or you can read his blog.

#4 The IN VIVO Blog

When the FDA asks ten nephrologists to review a medication and they all decline, the In Vivo Blog catches it.  This blog is well known for accuracy, quality and overall being an extremely useful read for those trying to keep up with the fast-moving pharmaceutical industry.

Best of all, they have a good sense of humor.

#5 Pharma Marketing Blog

Pharma Marketing blog gives you the expert analysis of John Mack, a man who knows a lot about the marketing tactics Pharma companies use – and constantly learns new things and shares his insight with readers.

Is Pfizer running a bait and switch with its Facebook fan page?  Is Allegran running an inappropriate advertising campaign for Botox?

Find out about these and other issues in marketing related to pharmaceuticals by reading what John Mack has to say.

#6 Drug Discovery Opinion

For people who care about pharmaceuticals, the Drug Discovery Opinion is gold waiting to be discovered.

This blog provides analysis of the technical issues that have tremendous implications for drug discovery, efficacy and marketability.  It explains the fundamental science that drives pharmacology.

Its authors have almost unmatchable credentials. Great read and quite useful.

#7 Pharma Strategy Blog

Which Tyrosine Kinase inhibitor shows the most promise?  What’s going on with Avastin and ovarian cancer?

To get the answer to these, and other important questions, Pharma Strategy Blog is excellently informative.  To get a sense of the value of its posts consider this.

Sally Church, the blog’s author, was responsible for helping launch Gleevec. 

Her expertise and talent shows clearly in her posts.  Pharma Strategy blog is top notch and it gives readers insider knowledge.

#8 The MacGuffin

Not a blog for the light of heart, The MacGuffin is infamous for no-holds barred criticism and analysis.

They see things other people don’t.  And they deliver their thoughts in a combination of colloquial and scientific talk. They might deliver a knock-out analysis of a medication and follow up with an inappropriate photo of a celebrity.

Cocky and clever.  Make sure to check out their analysis of schizophrenia.

#9 Pharma Conduct

This blog keeps an eye on the conduct of pharmaceuticals and the healthcare business.  It is mainly written by Eric Milgram, Ph.D. who has more than 10 years of pharmaceutical experience.

It is an investigative blog that is unafraid to expose corruption.  The formal, analytical training Eric underwent to learn chemical analysis shows through in the high caliber of his posts.

#10 The Science Business

Well written, useful and insightful.  Not as willing to take risks and focus on emerging issues as some others on this list, this blog makes the list because it provides extremely high quality writing on health care issues.

Sadly, BioJobBlog did not make the list. I guess I just have to work a little harder.

Until next time...

Good Luck and Good Job Hunting!!!!!!!

 

An Update on Pharma Blogs

Blogs first began appearing on the web about 10 years ago and most experts agree that they ignited the social media revolution. While blogs are the oldest form of social media, many pharma companies are reluctant to contribute to the content of the blogosphere. This is mainly because of perceived regulatory and legal issue and consequences. Nevertheless, a few intrepid big pharma companies have taken the social media plunge and currently maintain blogs with various formats and content.

From time to time, Mark Senak, author of the outstanding EyeonFDA blog, likes to check up on pharma to see how their social media experiments are going. In a post today, entitled “A Profile on Blogging By Pharma and FDA” he provides an update on pharma bloggers who he thinks are making a contribution to the life sciences community. The following is Mark’s assessment:

Johnson & Johnson–With JNJBTW, J&J has been blogging longer than any other pharma company with an archive going back to June 2007.  JNJBTW provides works to forge relationships with a broad spectrum of healthcare consumers by providing insights and resources for a variety of treatment related issues and profiles of company activities.  The blog haws multiple authors and accepts comments, though reviews them before posting according to the comments policy.  The blog has its own domain.

GSK–The More Than Medicine blog goes back to January 2009 and uses multiple authors to cover a wide span of subject matter that includes corporate social responsibility topics, chronic diseases, and current events. According to its comments policy, the blog allows for moderated comments. Entries can vary in terms of timing; with all three entries for October appearing on the same day.

AstraZeneca–Like JNJBTW and More Than Medicine, the AZHealthConnections blog takes a generalist approach by providing information on a broad spectrum of subject matter – some disease or condition specific in the areas of cancer and diabetes – but also including a public policy and general healthcare information. Residing in its own domain, the earliest archive is in October 2009 and the blog permits moderated comments according to its comments policy.

Lilly–The blog LillyPad is a more recent entry to the blogosphere begin in third quarter 2010, though no archive link is available on the landing page. LillyPad was started with a twitter handle as well of the same name, and more recently joined by a LillyPad YouTube channel called the Lilly Health Channel. The posting on the blog have frequent postings related to public policy and advocacy issues, though there is sometimes a posting on social responsibility or what it is like to work at the company. However, the focus on advocacy and policy issues (supporting innovation) seems to drive this effort in a very specific direction – being less generalist than other approaches. The comments policy is at the end of a post and states that comments are filtered – or moderated – by the company before posting.

Sanofi US–Here a company has taken a much more specific approach with a blog called Discuss Diabetes. The archive goes back to January 2011 and is therefore the newest entry and has the distinction on being the only disease/condition-specific target audience.  The blog, with its own domain, accepts and moderates comments. The focus is to provide information and resources regarding diabetes and resources for those who have it or are care partners, including such assets as its own mobile app for diabetics – Go Meals.

Pfizer–The Think Science Now blog on the Pfizer site has multiple authors who write to translate the science of medical research, though it lacks some of the traditional characteristics of a blog, such as an archive or commentary policy that was readily apparent. However, it is exemplary of the effort to aim at a specific audience of people rather than go broadly to the consuming public.

FDA–The FDA Transparency Blog first posted in November 2008 and was originally set to run for six months.  The purpose is to provide insight into how and why the agency comes to some of its decisions.  It does not have its own domain but is contained in the labyrinth of the FDA’s website.  The blog allows for moderated comments according to its comments policy, though I have not found that to necessarily be the case.

As you can see, there are not many pharma companies that maintain corporate blogs. Perhaps this may change after FDA releases it guidance on the use of social media in the life sciences industry. That said, it is anybody’s guess as to when that guidance will be issued; it already has been two years and there is no guidance yet!

Until next time...

Good Luck and Good Job Hunting!!!!!!!!!!

 

 

Occupy Novartis?

Angry with recent job cuts announced by the Swiss pharmaceutical giant Novartis, protesters, this past Saturday, gathered in Basel and beside the villa of its former CEO and Chairman Daniel Vasella to express their displeasure with the company’s decision to layoff workers.

In Basel, about 1,000 people gathered and demanded that Novartis reverse its decision to layoff 1,100 people who work at the company. Meanwhile, about 20 protestors gathered in a field opposite Vasella’s walled lakeside Mansion. Two of the protestors handed Vasella a “fake pink slip” and according to witnesses he laughed and took the gesture in stride.

Vasella, who is not a stranger to protests, is one of Switzerland's highest-paid executives and in 2009 animal rights activists set fire to his Tirolean hunting lodge to protest Novartis’ use of animals to test pharmaceuticals and consumer products. 

Currently, the Occupy Wall Street movement in the US has primarily targeted banks and financial institutions. However, two weeks ago, a group of protestors in Croton, CT, staged a demonstration at Pfizer headquarters to express their anger a recent layoffs announced by the company.

Until next time...

Good Luck and Good Job Hunting!!!!!!!

 

Alternatives to Pharma Jobs: Working For CROs and Biotech Start Ups

In today’s tough economy, one of the more challenging things after graduating college or graduate school is finding a job. Many life sciences graduates are beginning to realize that skills and training that they received in college have not adequately prepared them for jobs in the real world. Furthering, “previous industrial experience” is almost always a requirement for most jobs at pharma and biotechnology companies. As many students ask me “How can we get previous industrial experience if nobody will hire us to get that experience?” 

While this may appear to be a typical “Catch 22” situation, it is not an insurmountable one A convenient way to acquire the requisite previous industrial experience is to volunteer or land an internship (paid or otherwise) at a small, local life sciences company. Many of these companies can use the help and will gladly give you an opportunity as long as they don’t have to pay you much. Another strategy is to seek employment contract research organizations (CROs) like Huntingdon Life Sciences. These companies conduct research for their pharmaceutical and biotechnology clients and are frequently willing to hire relatively inexperienced but talented scientists into entry level jobs. This is because the demand for well-trained scientists continues to grow at CROs as more and more pharma and biotechnology companies outsource R&D activities and continue to shed jobs. 

Another option is to look for entry-level jobs at local start up companies. Typically, most of these companies are venture-backed and have limited financial resources. Consequently, salaries offered by these companies to employees are generally lower than those at CROs, biotech and pharmaceutical companies. Nevertheless, while you may not get paid as much as you expected or like, working as a research scientist at a start up company definitely counts as industry experience and it may help to jump start your career in the life sciences industry. 

If you cannot get a job at a CRO or a local start up, you can always start your own company! However, while this may sound like an exciting idea, it is probably a good idea get some entrepreneurial training before you take the leap. For example, Washington University offers a program called the BioEntrepreneurship Core, which combines biomedical research methods with business and entrepreneurial skills. The program offers outreach programs that connect would-be entrepreneurs with business and financial leaders in the St Louis, MO area. Also, it frequently hosts networking events and has access to state resources that can be allocated for new ventures and start ups.

According to a recent article in the St. Louis Post Dispatch, the city of St Louis has many life sciences graduates, but lacks the businesses to employ them all. To that end, BioSTL, a local initiative backed by hospitals, research facilities, and private investors was recently created to build a life sciences industry in St Louis and provide jobs to its talented pool of life sciences graduates and scientists. Ultimately, BioSTL hopes that its efforts will allow the St Louis metro area compete with established biotechnology markets on the East and West Coasts.

Finally, it you cannot land a job at a CRO, a local start up or you are not interested in starting your own company, you can always go back to graduate school. However, if you choose this path, then I highly recommend that you do some research to determine which jobs are likely to be in high demand over the next 5 to 10 years! While going to graduate school may help to defer repaying your undergraduate students loans, you run the risk of incurring more debt and possibly not have a job after you graduate unless you choose your next career option wisely.

Until next time...

Good Luck and Good Job Hunting!!!!!!!!!! 

 

Some Practical Twitter Advice for Jobseekers

I just returned from the AAPS meeting in Washington, DC and I was very surprised to learn that many graduate students and postdocs have heard of Twitter but don’t know exactly what it is or how to use it! Because of this, I decided to write a post that offered a step-by-step approach for using Twitter as a job search tool for life scientists who may be looking for jobs. However, much to my delight, I found a recent post on the Secret of the Job Hunt website that provides a great “how to” guide on Twitter use for jobseekers. 

The post entitled How to Use Twitter to Find a Job” was written by Erin Kennedy, CPRW, CERW a certified career counselor, resume writer and blogger is a great introduction to using Twitter and she provides insightful tips on how to maximize Twitter’s potential as a job searching tool.

How to Use Twitter to Find a Job

by Erin Kennedy, CPRW, CERW 

For any newbies to social networking, it might seem unusual to use a site such as Twitter to find a job. However, many people can find the right contacts on Twitter to help them to find a job–but it can be a little complicated in 140 characters or less? When using Twitter as a job search tool, it is best to keep content as neutral and professional as possible. Remember, as with anything you write and post online, once you “tweet” it’s out there FOREVER.

The first thing to do when starting up a Twitter account is to choose your user name wisely and word your 160-character bio in such a way that it becomes more searchable, or Google-friendly. Your bio should share a little bit about your career so that when other people look up that keyword, you can gain more traffic to your profile. An avatar will also make your profile more appealing. Choose a professional portrait or a simple picture in which you’re facing the camera and you are not accompanied by anyone else.

A basic rule of thumb when it comes to using Twitter as a job-search tool is to keep content favorable to anyone who might stumble across it – your tweets should balance your work and personal life. If you are looking for a job, you can tweet about the types of jobs in which you are interested. Also, you can tweet about your hobbies or interests so that employers get an idea of what you are like outside of work.

In that same vein, keep in mind that there are many recruiters who actually look to Twitter for new hires because it gives them something of a real-world perspective of what that person is like. In an extremely competitive economy, where plenty of people are qualified for the same job, many companies look at an applicant’s personality to see whether they would be a good fit in the company’s culture. In this case, it helps to follow these recruiters for the companies in which you are interested.

On a similar note, you can connect with these recruiters and industry leaders and show them your interest in their tweets. You can either “retweet” to forward their tweets along or you can address them directly by putting the @ symbol before their user name. By keeping in touch with these people, you will have access to the latest information in your industry. Therefore, when you are called in for a job interview, you will have that extra edge over other candidates by speaking confidently about your knowledge of their field.

Like any real-world networking situation, a Twitter presence cannot be expected to build overnight. It takes time and patience; however, by connecting with the right people, you might very well find your way to your dream career. The key to a successful Twitter profile is keeping it professional with a glimpse of your personality, hobbies and interests outside of work as well.

Until next time...

Good Luck and Good Tweeting!!!!!!

 

Emerging Job Opportunities in the Life Sciences Industry

I just returned from the American Association of Pharmaceutical Scientists (AAPS) meeting in Washington DC where I gave three talks about biocareer development strategies. One of the talks, "Emerging Job Opportunities in the Life Sciences Industry" was reported on (see below) by a writer from Fierce Pharma.  While I don't usually "too my own horn." about my achievements, I thought a Number 2 ranking in the publications daily top 10 list was certainly worth a mention.  

 
New job opportunities emerging in Big Pharma
October 26, 2011 — 7:24am ET | By Maureen Martino

Since 2001, 300,000 pharma employees have lost their jobs, primarily in R&D and sales. That's according to Clifford Mintz, the founder of BioInsights, which develops and offers bioscience education and training. Mintz spoke at a session on new job opportunities in biotech and pharma at the annual AAPS meeting in Washington, D.C. While the losses have been steep, they're balanced by emerging, in-demand careers in the industry.

The industry's struggles are well-known: Many companies are facing loss of exclusivity on their biggest sellers but have little in the pipeline to pick up the slack. Productivity is dropping as the cost of bringing a new drug to market soars. Government and payors want more effective drugs for less money. The list goes on.

Developers are looking to new markets and new technologies to address these issues. But how do these trends play out for the pharma job seeker? Many people, particularly Ph.D.s, may have to consider getting additional training if they want to land their dream job. "Companies used to be willing to just hire smart people. But with the economic downturn and global competition, companies can no longer afford to invest in people who have promise. They need to see proven skills," Mintz explained. With the right blend of skills and experience, however, there still some pharma jobs that are in demand.

Clinical Research and Regulatory Affairs

"Clinical research is the lifeblood of the industry," Mintz said. As developers expand in emerging markets, there's a particular demand for people to manage and organize overseas clinical trials. "There's a huge need for clinical research professionals worldwide," he said, noting that most Phase I and II trials are conducted outside of the U.S.

Another one of the industry's perennial needs is regulatory affairs professionals. "Regulatory affairs experience is a skill that all companies large and small would die to get their hands on," explained Mintz. The increasingly complex and uncertain world of FDA regulation--particularly when it comes to new technology and science--means that companies are always on the prowl for individuals with solid regulatory knowledge and ability to interact with the FDA. You can read more about the demand for clinical research and regulatory affairs jobs here.

Biomanufacturing

The pharma industry's interest in biologics remains strong--just look at Sanofi's buyout of Genzyme, or Roche's purchase of Genentech. They're lured by disease-altering biologics that are less likely to face generic competition than traditional drugs. As a result, there's been increased demand for professionals who can navigate the complex world of biomanufacturing. Those with a background in upstream and downstream processes, large-scale protein purification, fermentation technology and bioengineering can make the transition to biomanufacturing.

Healthcare Information Technology

The rise of bioinformatics and genomics coupled with the push for electronic medical records has created jobs in healthcare information technology. Health informatics--the intersection of healthcare and IT--is ideal for people with expertise in genomics, bioinformatics or software that understand how to work with and manipulate large data sets and databases. The Obama administration has made EHRs a priority, and there's a need for software engineers and biologists who are comfortable working with medical information.

Medical Devices

"The medical devices industry has been experiencing explosive growth for the past decade," Mintz said. Regulatory hurdles in the medical device industry are much lower than they are for biologics or small molecules, making the industry a more stable alternative to biotech and pharma. The demand for devices, which address problems that can't be treated with medicine, will continue to grow as the population ages. Job seekers with strong backgrounds in bioinformatics, genomics, engineering and translational medicine are best suited to this field.

Medical Communications

Medical communications--which includes medical writing, editing, graphic design and science journalism--continues to boom. The demand for these jobs has risen because companies need a slew of communication materials to send to patients, physicians, researchers, investigators and the general public about their products and business.

Patent Law and Technology Transfer

Recent changes to U.S. patent laws have increased the demand for patent agents and patent attorneys in the life sciences field. Pharma's growing reliance on basic research from learning institutions means that there's a need for technology transfer experts. These experts manage the patent estate and intellectual property of universities and colleges that may engage in licensing deals with the industry. A law degree is a must to compete in this field.

Until next time...

Good Luck and Good Job Hunting!!!!!!
 

Optimizing LinkedIn As A Job Search Tool

While LinkedIn is not considered by many to be a “true” social networking site (some consider it to be little more than a place to post an electronic resume), it is increasingly becoming the place to go to look for or find a job. Most recruiters and many hiring managers used LinkedIn to source qualified candidates for job open at their organizations. That said a well-thought-out and carefully written LinkedIn profile can make the difference between employment or not.

To that end, I came across a great article entitled “Five Minutes to Optimize Your LinkedIn Profile”. Its author, Ian Levine, provide some excellent advice and tips about how to craft a LinkedIn profile so that you will be found by recruiters and prospective hiring managers. Not surprisingly, the key to success is peppering your profile with keywords that are contained in standard job ads in your industry. According to Levine, LinkedIn appears to scan only four categories: Professional Headline, Titles, Specialties and Industries. LinkedIn scans these categories for frequency of the keywords selected.

One way that Levine recommends to assess whether or not your profile is a good one is to enter specific keywords that are consistent with the type of job(s) that you are interested in landing. If your profile comes up at the top (or close to it) of these types of searches than your profile is a good one. A failure to appear in the search results suggests that your profile may need some additional work to land a job!

Until next time...

Good Luck and Good Job Hunting!!!!!!

 

Twitter is the Social Medium of Choice for Big Pharma And Biotech Companies

Despite the initial pushback against social media by many pharma and biotech companies it appears that Twitter is emerging as the medium of choice for the life sciences industry. The main reasons for this trend are the 140 character world limit and the real time nature of Twitter. Unlike Facebook pages and blogs, where visitor’s comments (of any length) remain for indefinite periods of time, the information contained in tweets is minimal and their exposure time is second or minutes rather than days or months. These features allow pharma and biotech companies to more easily manage information flow and quickly implement damage control when necessary. 

Because of the growing importance of Twitter in life sciences circles, Mark Senak, the intrepid author of the EyeonFDA blog and a self-proclaimed social media enthusiast, compiled a list of well, useful pharmaceutical Twitter lists. Twitter users can subscribe to lists which are a compilation of tweets from persons who belong to the lists. For those of you who use LinkedIn, Twitter Lists are analogous to LinkedIn Groups.

Mark recommends the following lists to those who want to follow the pharmaceutical/healthcare industry

Healthcare Reporters 

Pharmaceutical Manufacturers 

Device  Manufacturers

Medical Journals

FDA Twitter Feeds.

Government Healthcare

Pharmaceutical and Biotech Jobs

To view these lists you must be a Twitter member!

Hat tip to Mark and to John Mack at the Pharma Marketing Blog for the Twitter image!

Until next time...

Good Luck and Good Tweeting!!!!!!!

 

Amgen Hires Tony Hooper and Lays off Nearly 400 Employees

Last week Amgen announced that it was reorganizing its R&D structure and that layoffs were likely. Today, the company announced that it had hired Tony Hooper, very recently the former senior vice president, Commercial Operations, and president, U.S., Japan and Intercontinental at Bristol Myers Squibb (BMS) to overhaul commercial operations. Shortly after the Hooper announcement almost 400 Amgen employees learned that they would lose their jobs.

Hooper will replace Jim Daly as executive vice president of commercial operations at Amgen. During his 16 year tenure at BMS, Hooper ran commercial operations for all of BMS’ products in both mature and emerging markets.

Amgen is reorganizing its R&D efforts because its EPO franchise revenues are declining and it is preparing to launch its recently approved osteoporosis drug called Prolia. According to a post on today’s Pharmalot blog the R&D overhaul is not an across the board reduction but will affect multiple sites. At present, Amgen employs about 17,600 workers worldwide.

Until next time...

Good Luck and Good Job Hunting!!!!!!!!!

 

Bristol-Myers Squibbs Shuffles Its Senior Management Team

Bristol-Myers Squibb (BMS) announced today that it had made major changes to its senior management team which is now headed by CEO Lamberto Andreotti.

Giovanni Caforio has been promoted to president, U.S. Pharmaceuticals. Caforio was most recently senior vice president, Oncology and Immunology Global Commercialization. In his new role, Caforio will report to Lamberto Andreotti, chief executive officer, and has been named a member of the Company's Senior Management Team.

In addition, Charles Bancroft and Béatrice Cazala have been appointed Executive Vice Presidents of Bristol-Myers Squibb. Bancroft will add to his role of Chief Financial Officer operational responsibility for the pharmaceutical business in Latin America, Middle East, Africa, Canada, Japan and several other countries in the Pacific Rim. Cazala will add responsibility for global policy to her role leading Global Commercialization, Europe and Emerging Markets. Both will continue to report to Andreotti and serve on the Company's Senior Management Team.

Anthony C. Hooper, senior vice president, Commercial Operations, and president, U.S., Japan and Intercontinental, has decided to leave the company. Hooper, a long time member of BMS's senior management team was obviously not on board with Andreotti's vision for the company's move to become a next generation biopharma company.

Until next time...

Good Luck and Good Job Hunting!!!!!!!!!!

 

Consolidation Continues in the US Life Sciences Industry

Earlier this week Roche Holding AG announced that it would pay $230 million to acquire the San Diego, CA-based biopharmaceutical company Anadys. The reason for the acquisition is to bolster Roche’s standing in the hepatitis C market which is projected to grow to as much as $15 billion annually by 2019.

Anadys has a fairly large experimental pipeline of hepatitis C drugs, the most advanced candidate being setrobuivr that is being clinically tested in combination with the generic antiviral drug ribavirin and Pegasys (PEGylated α-interferon) as a hepatitis C treatment.

The Anadys deal comes on the heels of an agreement last week between Roche and Merck & Co to jointly market hepatitis C treatments in the US. Merck recently won approval last May for Victrelis (boceprevir) the first new hepatitis C treatment in over a decade. Also, late last month Vertex Pharmaceuticals received approval for a new hepatitis C drug called Incivek (telaprevir). Anadys is also conducting early clinical trials on ANA773 as a possible treatment for hepatitis C infection, cancer and other chronic diseases.

In other news, GlaxoSmithKline (GSK) is rumored to be contemplating purchasing Maryland-based Human Genome Sciences (HGS), which recently received US approval for Benlysta a novel monoclonal antibody treatment for the autoimmune disease systemic lupus erythematous. 

Benlysta was the first new drug to be approved to treat lupus in over 50 years. GSK is HGS’s commercialization partner for Benlysta which is expected to be a blockbuster drug. The reason for the takeover rumors is likely HGS’s stock price which has fallen from 52-week high of $30 to its current value of $15 per share. 

Until next time...

Good Luck and Good Job Hunting!!!!!!!

 

Effects of Facebook on College Students

Facebook University
Created by: Online PhD

BioCareer Development Symposium

Last week, BioJobBlog in association with BVS, a life sciences vendor management company, launched an inaugural three hour career development workshop called BioCareer Development Symposium at New York University School of Medicine. 

The event which featured seminar topics  including "Writing a Winning Resume," "Interviewing Tips and Advice" and "Social Media and Career Development for LIfe Scientists" was well attended by graduate students, postdocs and mid-career life scientists.  In addition to the seminars, nine life sciences companies were on site to showcase the latest life sciences reagents, equipments and kits.

Future BioScience Career Development Symposia are scheduled @ Georgetown University, Johns Hopkins University, University of Alabama-Birmingham and the University of North Texas Health Sciences Center in Fort Worth, TX.

If your or your institution may be interested in hosting or learning more about our BioCareer Development Symposium offerings, please contact me.

Until next time....

Good Luck and Good Job Hunting!!!!!!!!!

Reputable Online Master's Degree Programs in Science, Engineering and IT

Online degree programs have exploded in the past 10 years or so and are now considered to be a legitimate way to earn a second or third degree to enhance the chances of finding a job in a tough economy. Further, an article that recently appeared in the NY Times “The Masters as the New Bachelor’s” suggested that Master's Degrees were supplanting bachelor degrees as the minimum requirement for employment in the US. Unfortunately, not everyone has the time to enroll in a traditional bricks and mortar Master's Degree program. This has forced many would-be students to enroll in online programs to earn a Master's Degree.

Like it or not, the reputation of the online institution that confers the degree will make a difference for jobseekers. In other words, an online Master's Degree from Penn State University will likely impress a hiring manager more than one from the University of Phoenix. With this in mind, my colleagues over at www.onlinemasters.org recently sent me an article entitled “The 15 Most Prestigious Online Master’s Programs” Most of the programs included on the list (see below) are relevant for those jobseekers interested in broadening their knowledge in the life sciences and healthcare, engineering and information technology (IT).

Auburn University: Electronically Delivered Graduate Education (EDGE) courses are offered online at the student’s convenience. Engineering programs include: Chemical Engineering, Civil Engineering, Computer Science and Software Engineering, Industrial and Systems Engineering, Materials Engineering, and Mechanical Engineering. Business programs include Accounting, Business Administration, and Management Information Systems. A combination MBA/MISE degree also is available.

Boston University: Boston University Distance Education offers master’s degrees in art education, criminal justice, music, computer information systems, health communication, management, manufacturing engineering, and social work. These programs provide students with an in-depth theoretical foundation as well as practical strategies for meeting demands of the marketplace. Many students have gone on to shape the future of their professions through their knowledge and leadership.

Carnegie Mellon University: Carnegie Mellon University’s H. John Heinz III College offers distance learning programs for Master of Science in Computer Science & IT (ranked #1 by U.S. News and World Report), Master of Medical Management (some onsite sessions required), and Master of Public Management (part-time and full-time tracks; work experience is required rather than GRE and GMAT).

DePaul University: Developing and providing degree programs for working adults for over 100 years, DePaul has been able to expand its reach by offering fully online master’s degree programs in various disciplines within the College of Computing and Digital Media, College of Education, and School of Public Service.

Duke University: By utilizing Duke’s resources in environmental science, engineering, policy, and business, the Nicholas School of the Environment’s Environmental Leadership Master of Environmental Management program gives students insight into the many aspects of environmental issues. The faculty includes recognized experts in the field whose research and publications affect important environmental and natural resource challenges.

Georgia Institute of Technology: Online master’s degrees are offered in aerospace engineering, computational science and engineering, electrical and computer engineering, industrial engineering, information security, mechanical engineering, medical physics, and operations research, in addition to a Professional Master in Applied Systems Engineering. Students study at their convenience, accessing a wealth of technological and industry knowledge while building a network of Georgia Tech faculty and industry professionals.

Indiana University: Kelley School of Business, through Kelly Direct, offers fully online MBA program, along with Master of Science degrees in finance, global supply chain management, and strategic management. There are also MBA dual-degree programs (mostly, but not fully, online) with Thunderbird (Master’s in Global Management) and Purdue (MSE and MS in Food and Agribusiness Management).

Johns Hopkins University: Here you’ll find master’s degree programs in bioinformatics, computer science, environmental engineering and science, environmental planning and management, and systems engineering — all can be completed fully online.

Michigan State University: In the online Master of Science in Criminal Justice program, students may choose to follow the general requirements for the Master’s in Criminal Justice, specialize in security management, or follow an international focus. Courses are offered entirely online, and are taught by the same faculty members that are involved in the on-campus program.

Pennsylvania State University: Over 100 years ago, Penn State founded one of the nation’s first correspondence courses. Now through their World Campus, they offer online master’s degrees in a wide range of areas including (to name a few) education, business administration, homeland security, nuclear engineering, and supply chain management. The online courses are flexible, yet the same academically challenging courses as on campus.

Stanford University: Students whose employers are members of the Stanford Center for Professional Development can earn Master of Science degrees while attending classes online on a part-time basis. Courses of study include aeronautics and astronautics, biomedical informatics, chemical engineering, civil and environmental engineering, computational and mathematical engineering, computer science, electrical engineering, management science and engineering, materials science and engineering, mechanical engineering, and statistics.

University of Florida: Most distance degrees may be taken on a part-time basis through this university. However, all degree programs require formal admission to the school. Master’s degrees are offered in various disciplines within the Colleges of Agriculture & Life Sciences; Business Administration; Design, Construction, and Planning; Education; Engineering; Fine Arts; Liberal Arts & Sciences; Nursing; Pharmacy; Public Health and Health Professions; and Veterinary Medicine.

University of Illinois: The Department of Computer Science offers a fully online Master’s in Computer Science program, which is restricted to off-campus professionals and is not intended for those who have access to on-campus courses and programs; although, all students receive the same lectures, class assignments, exams, and projects as on-campus students. The degree can be completed in as little as three years (at one course per semester), but must be completed within five years.

University of Southern California: USC Viterbi School of Engineering’s Distance Education Network (DEN) students view online the same lecture as on-campus students either live or at their convenience. Students interact by calling a toll-free phone number to ask the professor questions. Lectures are archived for the entire semester and can be downloaded.

Vanderbilt University School of Nursing: Vanderbilt’s School of Nursing offers a Master of Science in Nursing Health System Management. A Health Systems Manager is a registered nurse whose focus is on the management of health care delivery in various organizations. Graduates have the breadth of management knowledge and skills needed to perform effectively and assume leadership positions in health care delivery organizations.

Until next time....

Good Luck and Good Studying!!!!!!

 

How Failure Can Help a Career

Conventional wisdom suggests that failure or negative comments can be harmful or potentially damaging to the career trajectory of most people. While in many cases this may be true, sometimes they may have an opposite and unanticipated positive effect or benefit. This is certainly true for me.

Back in 1970, when I was a freshman in a mandatory first semester English Composition class, I clearly recall the time when the instructor decided to read aloud some of our first essays. Mine was selected and I swell with pride when my name was mentioned. I had fancied myself an excellent writer and I thought that she was going to use my essay as an example of outstanding writing. After reading my essay aloud, I expected laudatory comments and how wonderfully written it was. Imagine my shock, humiliation and shame when she excoriated my essay and used it as example of poor writing. I never forgot that moment and recall that at the time, I decided to “show” the instructor how wrong she was and dedicated the next 40 years to become the best writer that I could be. As many BioJobBlog readers may know, I am currently a professional medical/science writer. Despite my ability to make a living as a writer and no matter how many times I publish something, I never forget that moment in that long ago freshman composition class.

Until today, I thought that my experience was not common and somewhat unique. In her article entitled “How Insults Spur Success” Peggy Payne—a journalist and author of several books—tell a similar story of rejection and how it helped rather than hurt her. In Peggy’s case she was rejected at age 16 from a renowned summer camp for “brainy” teenage students. Despite her obvious successes as a journalist and author, like me, she has never forgotten the incident and like me, it continues to drive her to succeed. Likewise, she reports that her husband received a “devastating” F on his first philosophy paper in college. He has been a tenured faculty member for 35 years in the philosophy department at the University of North Carolina at Chapel Hill. 

In all of our cases, we decided to “show’em that they were wrong about us. And, interestingly, I think that “we have been trying to prove them wrong our entire lives. While this may work for some of us, it may not be universally true for others. In any event, the thing that most of us fear the most is failure. However, as many successful persons will tell you is that it took failure for them to realize their true potential. This is certainly true in my case. While not getting tenure was an overwhelmingly devastating event, that one failure freed me to explore other opportunities and discover that I can do other things beside research and be happier doing them than I ever would have been if I had received a tenured faculty appointment!

The point that I am trying to make is that failure, while scary, can actually be a good thing and help to define a live more positively than success. So, the next time that things are not going well for you, take a moment and analyze your situation. Then, attempt to figure out how you can turn a negative comment or presumed failure into a potentially positive outcome. While it may take some time to accomplish this, it certainly gives you a goal to work towards and ambition generally breed success!

Until next time...

Good Luck and Good Job Hunting!!!!!!!!

 

A New Way Forward for FDA?

Last week, US Food and Drug Administration (FDA) Commissioner unveiled a “blueprint” that contained immediate and actionable steps that can be taken to spur innovation in the life sciences. The report’s proposals stem from a review of FDA’s current policies and practices, as well as months of meetings with major stakeholders nationwide, including key industry leaders, small biotech, pharmaceutical and medical device company owners, members of the academic community, and patient groups. Entitled “Driving Biomedical Innovation: Initiatives for Improving Products” the report focuses on seven major actions:

  1. rebuilding FDA’s small business outreach services
  2. building the infrastructure to drive and support personalized medicine
  3. creating a rapid drug development pathway for important targeted therapies
  4. harnessing the potential of data mining and information sharing while protecting patient privacy
  5. improving consistency and clarity in the medical device review process
  6. training the next generation of innovators
  7. streamlining and reforming FDA regulations

The blueprint was issued in response to growing concerns that—despite record investments in biomedical R&D—the drug pipelines at many US life sciences companies has grown exceedingly thin. Not surprisingly, most life sciences companies blame the agency for the thinning pipelines but in reality both side have contributed to the problem. Hamburg’s bold plan seems reasonable. But, it can only be implemented if Congress provides sufficient funding to underwrite the new initiatives proposed in the plan. And, while these funds ought to be allocated, it is not clear whether or not it is likely given the poor economy and the current, unprecedented political divisiveness that exists in Washington these days.

Moreover, Mark Senak, author of the Eye on FDA blog, suggests that FDA can improve its effectiveness by learning how to communicate better with its stakeholders. Mark, a social media advocate provides this compelling insight into FDA’s communication problems and the agency’s inability to grasp that the Internet and social media can help to improve its communication skills:

"The extremely long track record of FDA in attempting to figure out the Internet (first public meeting held in October 1996) and social media (first public meeting held in November, 2009) has yielded no guidance, with little transparency into the process.  It is time for FDA to seek outside communications expertise to help the agency better formulate policy on a timely basis."

While I believe that Commissioner Hamburg’s blueprint for improvement is a good one, it isn’t clear whether she will get the necessary support to implement it.

Until next time...

Good Luck and Good Job Hunting!!!!!!!!

 

Sanofi Invests $300 Million in a Vaccine Manufacturing Facility in India

I am not sure how I missed this announcement last week but Sanofi Aventis will invest $300 million in a vaccine (biologics) manufacturing facility in India. The investment is in addition to the $784 million that Sanofi paid two years ago to acquire the Indian biologics company Shanta Biotech.

Sanofi executives originally thought that the purchase of Shanta would give immediately give them biologics manufacturing capability in South Asia. This did not occur because of manufacturing problems with the existing Shanta facility.  Sanofi claims to have corrected the manufacturing issues and investment of an additional $300 million into the facility is to bolster both R&D and manufacturing capacity. The new manufacturing facility is consistent with Sanofi’s publicly announced strategy of earning as much as 40 percent of its profits in emerging markets by 2015.

Like China, emerging markets like India, Brazil and Russia will be squarely on big pharma’s radar for the foreseeable future.

Until next time...

Good Luck and Good Job Hunting (in India!)

 

Parity for Women in the Workplace Is Still Lacking

Despite the fact that women in the US earn nearly 60 percent of four-year college degrees and make up almost half of the American workforce, women held about 14 percent of senior executive positions at Fortune 500 companies. An even lower percentage of female scientists hold tenure track faculty positions. 

Sadly, the number of female executives hasn’t budged since 2005 nor has there been an increase in appointment of women scientists to tenure track positions. This phenomenon is analyzed in a recent article written by Phyllis Korkki entitled “For Women, Parity IS Still a Subtly Steep Climb.” Experts interviewed in the article contend that the inability of women to reach parity in the workplace can be attributed to “entrenched sexism” in the workplace that is present both sexes. Ms Korkki describes how this plays out in the workplace and how it can be overcome by both men and women. 

The article is a fascinating and insight read: I highly recommend it!!!!

Until next time...

Good Luck and Good Job Hunting!!!!!!!!!!

 

Okay, Maybe Big Pharma Layoffs Are Not Over: AstraZeneca to Eliminate 400 US Jobs

Astra Zeneca today announced that it will eliminate 400 positions at the company’s Wilmington, DE headquarters. Most of the cuts will be in sales and marketing and the downsizing is intended “streamline portions of its commercial business to best serve patients in the US.”

According to a press release, about 70 of the estimated 400 job cuts will come from existing unfilled vacancies. Also, employees will have the option to choose to potentially leave the company with a possible package. All decisions will be finalized by early December.

Like many of its competitors, AstraZeneca is facing fierce competition from generic manufacturers and downward pricing pressures. The company currently employs 61,000 persons worldwide including 14,000 in North America.

Until next time...

Good Luck and Good Job Hunting!!!

 

Are Pharma Layoffs Over?

From 2001 to present, roughly 300,000 pharmaceutical employees have lost their jobs. That is a massive number; second only to the job losses in the automotive and financial services industries. The main reasons for the layoffs have been a lack of return on investment on R&D activities and impending patent cliffs in 2013 for as many as 15 blockbuster drugs. 

Ed Silverman who runs the Pharmalot blog speculated in a post yesterday that the number of pharma layoffs may be dwindling. His assertions are based on an analysis of the annual number of pharma layoffs provided by the outplacement firm of Challenger, Gray and Christmas. Ed’s wrote:

 “So far this year, pharma layoffs have totaled 19,076, and this includes the 13,000 job cuts planned by Merck, which is actually eyeing many foreign positions, therefore, swelling the latest tally. Last year, pharma eliminated 53,636 jobs, down from 61,109 in 2009, when annual layoffs peaked. In fact, the 2009 bloodletting was outsized compared with every other year - the next highest annual layoff tally occurred in 2008, when 43,014 industry cuts were announced. Between 2003 and 2007, the number of jobs that were eliminated ranged from about 15,000 to 31,000 annually, according to the firm.”

This led Ed to posit that the worst may be over and those pharma employees who still have jobs may be able to relax a bit. However, it is important to note (as Ed also points out) that many big companies are still purchasing or opening new  R&D and manufacturing facilities in emerging markets like India and China and more and more R&D jobs are being outsourced. Further, while many US pharma reps have lost their jobs hiring reps in emerging markets continues to explode. Interestingly jobs that are in demand and still available to Americans include those in regulatory affairs, compliance, IT, clinical operations and marketing. Unfortunately, these are very specialized jobs and many of those pharma employees who have been layed off lack the requisite skills to compete for those jobs!

While I think we may have seen the last of massive layoff in big pharma, smaller and less publicized layoffs will likely continue at many US life sciences companies. The downsizing trend taking place in America will likely continue until drug pipelines are populated with new candidates and life science executive realize that outsourcing R&D job is not a viable solution for their productivity problems.

Until next time...

Good Luck and Good Job Hunting!!!!!

 

Maximizing Patient Engagement During Clinical Trials

Recruiting, retaining and managing patients that participate in clinical trials for approval of new medicines and devices have becoming very challenging in the past decade or more. Ironically, the ready availability of experimental new medicines in the US for certain therapeutic areas including oncology, neuroscience and vaccines have forced life sciences companies and CROs to conduct many Phase I and Phase II trials outside of the US. In turn, the globalization of clinical trials has forced many sponsors to increasingly rely on e-based and mobile solutions for patient recruitment, retention and compliance.

The Advance Learning Institute’s conference entitled “Patient Recruitment, Compliance And Retention For Clinical Trials: Integrating The Latest Technologies With Traditional Tools To Maximize Patient Engagement” that will be held in Manhattan on October 24-26, 2011 will provide attendees with insights into the best practices to maximize patient engaged in clinical trials. Presentations will be given by a variety of pharmaceutical companies, CROs and academic institutions including Pfizer, Merck Research Laboratories, Shire Pharmaceuticals, Celgene Corporation, Quintiles, Omniscience Mobile, Albert Einstein College of Medicine and the Michael J. Fox Foundation for Parkinson’s Research. A complete agenda for the conference can be found here.

Those of you who mention BioJobBlog or BioCrowd when registering for the conference will receive a $200 registration discount.

See you at the meeting!!!!!!!

Until next time...

Good Luck and Good Job Hunting!!!!!!!

 

Boston-Based Life Sciences Job Opportunities

Interest in the diagnostic sector of the life sciences industry began to wane shortly after development of a test for HIV in the 1980s. However, the emergence of molecular diagnostics and personalized medicine coupled with the 2001 anthrax attacks and the SARS outbreak have helped to reinvigorate this sector. In fact, the diagnostic industry is one of the fastest growing segments of today’s life sciences industry. 

For those of you who may not know, diagnostics tests are regulated in the US as medical devices not therapeutic entities. And, for the most part, the regulatory approval process for diagnostic tests is less stringent and quicker than that required for FDA approval of new therapeutic agents.

Unlike most pharmaceutical and biotechnology companies, companies focused on developing new diagnostic products are hiring. Boston-based Immunetics, a diagnostic company that focuses on developing tests to detect viral and bacterial pathogens including HIV, anthrax and others, is currently looking to hire a regulatory affairs and sales and marketing professional (Product Manager). 

The requirements for the regulatory affairs position can be found here whereas the qualifications for the sales and marketing opportunity can be found here. Neither of the two positions requires a PhD degree. However, persons with PhD degree who possess a strong background in regulatory affairs or pharmaceutical sales and marketing experience will be considered.

For those of you PhD degree holders out there, getting additional training in regulatory affairs or sales and marketing (for those with a business bent) would be extremely useful for those of you seeking employment in the life sciences or medical devices industries.

Until next time...

Good Luck and Good Job Hunting!!!

 

Looking for a Job in the Life Science Industry? Try China!

By now, most BioJobBlog readers have heard that China is poised to become a world leader in the life sciences. As some of you may already know, over 80 per cent of the worlds active pharmaceutical ingredients (APIs) that are used to produce FDA-approved medicines are synthesized in China and exported to manufacturing facilities throughout the world. Further, not a day goes bye without a press release about a new partnership forged between multinational life sciences companies and a Chinese partner. Finally, the Chinese government is heavily investing in the life science industry in an attempt to manufacture medicines for internal use and to export. 

Therefore, it should come as no surprise that Chinese life sciences companies are hiring. One such company is ShangPharma Corporation. ShangPharma was established in 2002 and has locations in Chengdu and Shanghai, China. It is one of China’s largest contract research organizations and employs over 1,600 persons. The company offers discovery and preclinical development services in both chemistry and biology including API and biologics manufacturing. 

The company is currently looking for a person with a PhD or Masters degree with expertise in CNS and/or cognitive subhuman primates (cymologous and/or rhesus monkeys) models. This is a Group Leader position and the ideal candidate will have a background in pharmacology and neurosurgery. Strong communication skills and the ability to speak and write reports in English are required. Please click here for more information or to apply for the position.

While working in China may not be the first choice for most Americans, it may be ideal for foreign students who trained in the US and have a good command of the English language. Whether you are Chinese or American, a sobering fact to remember is that almost 300,000 American pharmaceutical employees have lost their jobs since 2001; making this one of the worst life sciences job markets in history!

Until next time...

Good Luck and Good Job Hunting!!!!!!

 

More Workforce Diversity is Needed in the Life Sciences

As scientists, we all  subscribe to the notion that diversity is a critical component to the evolution of any species. While we this is a well known fact, the life sciences industry, like others, struggles with workforce diversity mainly in the area of research and development. For example the number of minority students—blacks and hispanics—who receive PhD degrees is miniscule as compared with their white counterparts.  Graduate schools struggle to promote diversity in their programs but their efforts to date have been lackluster.

One of the factors that contribute to the lack of representation of minority students in the life sciences may be the lack of access to equal educational opportunities. With this in mind, the folks over at onlinecolleges.net sent me a post that has a plethora of information about the state of minority education in the US. I culled relevant information from the list and reproduced it for this post.

Stereotyping impairs performance

A startling Ohio State University study exploring the effects of racial stereotyping uncovered some very unfortunate truths. Nearly 160 African-American students were asked to write an essay about an average college student, either named "Tyrone" or "Erik," with the implication being that the former is black and the latter white. Those assigned Tyrone scored an average of 4.5 on a standardized test, while Team Erik ended up with 6.2. Although possessing equal academic aptitude, researchers believe prevailing stereotypes negatively impact performance — thus creating an unjust cycle reinforced by students and teachers alike. 

Hispanic high school students had the highest dropout rate in 2009

The National Center for Educational Statistics shows that 17.6% of Hispanic high school students drop out before completing their diplomas or GEDs. Reasons vary from kid to kid, of course, and do not necessarily denote poor grades or discipline. On a positive note, however, Hispanic dropout rates decline steadily every year, with 2008 seeing 18.3% of the high school population leaving before graduating. 

Minorities comprise 32% of undergraduate enrollees

Undergraduate enrollment has actually increased among all racial and ethnic demographics, although minorities remain heavily underrepresented on American college campuses. Only 32% of postsecondary students are minorities as of 2004 statistics, but their numbers increase yearly — certainly a positive trend. Between 1976 and 2004, Asians and Pacific Islanders experienced the highest rate of increase, boasting a whopping 461%. So while the number still seems low these days, minorities are definitely catching up on campus and enjoy more opportunities to have their voices heard and heeded.

Minorities comprise 25% of graduate enrollees

With increased minority undergraduate enrollment came more representation in graduate programs, though at a slower pace. 2004 statistics showed that 25% of master’s and doctoral students were minorities, up from 11% in 1976. The most rampant increase occurred among Hispanics, at 377%. Once again, there’s absolutely nothing "scary" about more opportunities and representation in higher education. But the numbers could definitely be higher, especially since more enrollees means more imperative to address diverse needs.

Minorities comprise 10.2% of private school principals

In total, of course, as statistics vary rapidly depending on what — if any — denomination owns and operates the schools in question. Seventh-Day Adventist institutions lead the way, with 26.4% minority principals. Administrators of black, non-Hispanic or Latino descent are most prevalent, particularly in Seventh-Day Adventist (17.7%) and Pentecostal (14.7%) schools. They also make up 5.2% of total minority principals. When it comes to private education, more needs doing to ensure minority students and staff alike see their requests properly met.

The majority of black and Hispanic students attend high-poverty schools

Statistics from 2005 school year revealed that black and Hispanic students populate high-poverty schools more than any other minority. The National Center for Education Statistics considers "high-poverty schools," which are those with 75% or more attendees receiving free or reduced-price lunches. Forty-eight percent of black and 49% of Hispanic 4th graders hail from such desperately wanting institutions, while Asians and Pacific Islanders are more evenly distributed across economic demographics. 

Hispanic and black students are less likely to have internet access at home

Because of this, they adapt to classroom technology at a slower pace than their white, Asian and Native American peers. Twenty-six percent of Hispanic and 27% of black students use the internet at home, compared to 58% of Asian and 47% of Native American kids, resulting in a very unfortunate achievement gap. Numbers are improving, of course, but there’s still a ways to go before the gulf starts shrinking.

Schools with black or Hispanic majorities are more likely to hire underqualified or novice teachers

In fact, 25% of math educators at schools with 50% or more black students do not hold a degree or any other qualifications in the subjects they teach — probably the most egregious example. And once said teachers rack up the experience, they usually flee to more affluent (and white) areas. Such an unfortunate and enduring phenomenon plays a major role in perpetuating, if not outright widening, the achievement gap. Without knowledgeable, experienced and engaged teachers, students in affected schools typically lag behind and never receive the academic opportunities that should be afforded all youngsters. 

More black students repeat grades than any other racial or ethnic demographic

Both genders, too. In 2007, 25.6% of black males and 15.3% of black females between kindergarten and 12th grade had repeated at least one grade. These numbers, though, only reflect the issue as it relates to public school students. 

More black students receive suspensions and expulsions than any other racial or ethnic demographic

Between 6th and 12th grades, the 2007 school year saw 49.5% of black males and 34.7% of black females reporting that they had received at least one suspension in their academic careers. When it comes to expulsions, 16.6% of males and 8.2% of females said they had been dismissed from school at least once.

Hispanic teenagers have the highest pregnancy rate

In 2007, 81.7 out of every 1,000 Hispanic teenage girls gave birth — more than any other race or ethnicity. Across all demographics, however, the numbers are steadily decreasing.

This probably has something to do with improved sex education and easier access to necessary birth control devices, though the problem still requires considerable intervention. Especially since popping out babies as a high schooler is all trendy these days.

Clearly, until some of these problems are addressed, then it is likely that workforce diversity in the life sciences will continue to lag.

Until next time...

Good Luck and Good Job Hunting!!!!!

 

Employment Update: Some Biomanufacturers and Biotech Companies are Expanding!

While big pharma companies continue to shed jobs, there are some indications that the biotechnology industry is beginning to pick up some steam. For example, Boehringer Ingelheim (both a drug development and biomanufacturing company) is planning a $383 million expansion of its facilities in Ridgefield, CT. Likewise, Cary, NC-based Biologics a biotech cancer treatment company expects to almost double it staff from 85 to about 150 employees by the end of 2012. Finally, Gilead Sciences is undertaking a massive expansion of its Foster City corporate headquarters and expects to increase its workforce there from 1,700 to as many as 3,400 workers.

Although these expansions are only a few in number, they may be a harbinger of things to come in the US life sciences industry. One can only hope!

Until next time...

Good Luck and Good Job Hunting!!!!!

 

UK Regulatory Agency Considering Using Social Media for Adverse Events Reporting

Over two years ago at the beginning of the social media/pharma debate, I proposed that social media platforms like Twitter and Facebook would be great for adverse event reporting for drugs, biologics and medical devices. At the time, the suggestion was largely ignored and relegated to the category of “unlikely to happen anytime in my lifetime.” 

Imagine my delight after reading a post on today’s Pharmalot Blog which suggested that the Medicines and Healthcare products Regulatory Agency (MHRA)—the UK equivalent of the US Food and Drug Administration (FDA)—is considering whether to allow the public to use Twitter and Facebook to report side effects and adverse events.

According to the Pharmalot post:

"The MHRA is now “actively working on introducing other ways of reporting to make it easier and encourage more reporting,” Mick Foy, the MHRA group manager for vigilance and risk management of medicines, tells GP. “Applications for smartphones, improved web reporting forms and the use of social media such as Twitter and Facebook are being carefully considered as potential routes for reporting.”

While the MHRA is considering the use of social media, it is not clear that the agency will ultimately adopt Twitter, Facebook or other mobile applications for adverse event reporting. Like in the US, possible adverse reported in the UK must meet several criteria before they are verified and considered to be reportable adverse events. Despite potential problems and pitfalls, the fact that the MHRA is even considering social media as a means to improve adverse event reporting is laudable; considering the fact that FDA has yet to provide guidance on the use of social media in the US life sciences industry. Many companies, social media advocates and mobile app developers have been waiting for the said guidance for almost two years now.

Like it or not, social media is now part of the social fabric of today’s world. Rather than fighting its implementation, life sciences companies would use their considerable creative talent to figure out how to integrate and leverage social media (in non-promotional ways) to their benefit.

Until next time...

Good Luck and Good Tweeting and Following!!!!

 

New Group To Examine Ways to Help Graduate Students Move Into Careers

According to an article that appeared in the online version of The Chronicle of Higher Education website the Council of Graduate Schools and the Educational Testing Service  last Thursday that they are creating a commission to study and recommend ways to help graduate students move more easily through their training and into careers.

The commission aptly named The Commission on Pathways Through Graduate School and Into Careers, is composed of college officials and business leaders and will examine how much graduate students know about their career options once they obtain their degrees. Further it will also look into how students learn about their professional opportunities after graduation and the role of graduate programs in guiding students in their transition to a career.  The findings uncovered by the commission will likely be reported sometime next spring.

Ironically, the impetus for creating the commission was a report released in 2010 that urged the US to make it a national priority to improve graduate education and attract more students to pursue graduate degrees to prevent the country’s decline in global competitiveness. By 2018, the report estimated about 2.5 million more jobs will require graduate degrees. I am not sure what the authors of the report were smoking at the time that they prepared it, but I for one do not think we need more people with advanced degrees; especially in the life sciences. That being said, since the PhD-producing machine will not stop until tenure is abolished, the next best thing is for graduate programs to provide incoming students with a “real-life” perspective on career opportunities and the training necessary to pursue them. At present, career development programs and career counseling services are virtually non-existent at most universities and colleges. 

While formation of the commission is laudable, I am not convinced that it will accomplish anything except possibly assuage growing graduate student and postdoc discontent at many academic institutions. The reason why my expectations are low is a comment made by Patrick Osmer, the commission chair and vice provost for graduate studies and dean of the Graduate School at Ohio State University, who said

“It is important to create a dialogue with graduate students and with employers, and to listen to the students' concerns and expectations about career paths beyond academe.”

Personally, I don’t think that the lack of dialogue between graduate students and prospective employers is the problem. The real problem is the lack of care development discussions between graduate students and their advisors; many of whom don’t know or care about career options for the persons who they train. Until graduate programs recognize that career development counseling and training are in their bailiwick, then nothing is going to change regardless of findings of one or more “expert” commission run by individuals who are part of the problem!

Until next time...

Good Luck and Good Job Hunting!   

 

Link Longevity

As a blogger and an occasional Twitter user (believe me I would tweet more if I didn’t have to work for a living), I have often wondered how much of an impact that the links I post have on readers and followers. While there is little doubt that the posted links persist into perpetuity, it was not clear how long people continued to click or follow the links after they were posted. That is; until now!

According to new research by Bit.ly, the URL shortening service, most links shared online don’t live very long. The longevity of different links was determined by calculating the “half-life” (the point at which a link received half of its total online clicks) of links posted on Facebook, Twitter, YouTube, e-mail or chat clients.  

After analyzing 1,000 popular links on Bit.ly, it was determined that the average half-life of a link on Twitter was 2.8 hours. Links posted to Facebook lasted slightly longer at 3.2 whereas the longevity for e-mail and chat links was 3.4 hours. Interestingly, the average half-life of YouTube links was 7.4 hours and that of news-related links was a mealy five minutes! 

The conclusion—people spend way too much time watching videos on YouTube and pay little attention to current events. Duh, like I didn’t already know that!

Until next time...

Good Luck and Good Link Following.....

 

Seattle Biotech Dendreon To Lay Off 500 Employees

Dendreon, one of Seattle’s hottest and most visible biotechnology companies, yesterday  announced that it will lay off 500 employees or 25 percent of its workforce. The company’s only product Provenge—a prostate cancer vaccine that received FDA approval over a year ago—has been slow to be adopted and is lagging in sales. As of August 31 Dendreon had only 600 million in cash and investments. 

Dendreon staffed up to about 2,000 employees in anticipation of brisk sales of Provenge. Approximately, 100 jobs will be cut in Seattle and an additional 400 will be slashed at the company’s manufacturing facilities in New Jersey, Atlanta and Los Angeles. Because Provenge is a personalized prostate cancer vaccine, the company needed to create manufacturing facilities in close proximity to hospitals where patients are treated.

According to an article in the Daily Advantage “Dendreon reported in early August that quarterly gross revenues were only $51 million, about $7 million short of analysts' expectations, and it withdrew earlier projections that sales for the year would soar to $350 million or $400 million.”

Some BioJobBlog readers may recall that FDA approval of Provenge was not without some drama. There were allegations that there were conflicts of interest among several members of the advisory committee that FDA assembled to review the product (several members of the committee failed to disclose that they were consultants to companies that were competing with Dendreon for prostate cancer treatments). 

One of the main reasons for the slow sales of Provenge was the delay in reimbursements for physicians who used the product. It sometimes took Medicare, the largest provider of medical insurance in the US, three to five months to reimburse them.

Provenge costs about $93,000 for a three-stage course of treatment. According to the FDA, Provenge can increase the median survival time of patients with asymptomatic or minimally symptomatic metastatic castrate resistant (hormone refractory) prostate cancer.

Until next time..

Good Luck and Good Job Hunting!!!!!

 

Pharma and Social Media: Lilly Launches A YouTube Channel

Mark Senak, author of the outstanding EyeonFDA blog, tweeted today, that Eli Lilly & Co had launched a YouTube Channel. According to a post on the company’s blog Lilly Pad, its new channel dubbed the “Lilly Health Channel” will “videos on health and wellness, employee and community outreach efforts, health innovation, Lilly programs and other non-product-branded initiatives.”

While the announcement of a launch of another pharma-sponsored YouTube channel is no longer new or novel, Eli Lilly has been trying to transform itself into a modern, social media and crowdsourcing-focused pharmaceutical company. For example, Lilly is one of only a handful of big pharma companies that sponsors its own corporate blog. Moreover, the company is a leader in using so-called crowdsourcing to discover and develop potential new drugs. It has spun off at least two ventures that utilize a crowdsourcing approach to new drug discovery. Finally, unlike most other big pharma CEOs, its chief executive John Lechleiter has been outspoken about the lack of innovation and available workforce talent in the US life sciences industry. 

Is Lilly truly the pharmaceutical company of the future? That remains to be seen! 

Until next time... 

Good Luck and Good Viewing!!!!

 

Post Labor Day Job Cut Report

Despite the fact that no new jobs were added to the US economy in August, things were pretty quiet in the pharmaceutical layoff space. From what I was able to find, it appears that Alcon Laboratories will be moving about 100 jobs from Atlanta to Fort Worth Texas (I was recently in Fort Worth for the first time and I extend my sympathies to those Atlantans that may make the move). The consolidation is taking place because Novartis purchased Alcon in April and after acquisitions these sorts of things happen. Nestle, another Swiss company, had a majority ownership in Alcon. 

Interestingly, there appears to be some consolidation also taking place in the contract manufacturing space. Contract Pharma announced that it would close its Buffalo, NY manufacturing facility (purchased from Bristol Myers Squibb in 2005) and eliminate 128 jobs. Those employees who do not lose their jobs may have an opportunity to work in a nearby Ontario, Canada site. Likewise, UK-based United Drug, another CMO, will cut 150 jobs because of government-led regulatory decision to reduce health spending.

While none of these announcements were particularly noteworthy, Sanofi-Aventis’ announcement today that it will cut $2.9 billion in costs over the next few years was somewhat shocking but not unexpected. Most of the cuts will be in R&D and there will undoubtedly be massive downsizing and reorganization. 

According to a post on today’s Pharmalot blog “a presentation indicates that research and development costs are in the process of being cut by 12 percent from 2008 to about $1.1 billion, excluding Genzyme. And the total headcount over this same period is being reduced by about 22 percent, from roughly 13,000 positions to about 10,000 jobs by the end of this year, again excluding Genzyme.”

Today’s announcement of cut back is consistent with Sanofi’s business strategy over the past year or so which included plant closings and large sales rep layoffs Again, the Pharmalot blog reported “The upcoming round involves slashing about $700 million in expenses from Genzyme, the biotech that Sanofi purchased recently, as oncology units in the Boston area are combined.”

The cost cutting measures are in response to the impending loss of patent exclusivity for several of its blockbuster products most notably Plavix and unexpected attrition in the company’s late stage clinical development portfolio. This year sales of products facing patent expiry are expected to decline to $4.2 billion as compared with $10.6 billion in 2008. To cope with these difficulties, Sanofi has gone on a buying spree over the last couple of years spending $23 billion to acquire various companies with Genzyme being the crown jewel.

Meanwhile, Sanofi plans to file for approval of six new drugs this year and hopes that it can introduce 19 new drugs by 2015. I suspect that Sanofi’s aggressive M&A strategy may help the company reach that goal. That said, if I was a Sanofi or Genzyme employee, I would be dusting off the old resume right about now.

Until next time...

Good Luck and Good Job Hunting!!!!! 

Combining Business and Biology to Increase Career Options

If you received your bachelors degree in biology or a related field, there is a good chance that you are having difficulty finding a job. The lack of an advanced degree in the life sciences can  hurt your chances of securing a job mainly because most life sciences jobs demand more education and experience Choosing to pursue a business degree can be a step in the right direction to advance your career.

Receiving an advanced degree from traditional or online MBA programs can vastly improve the likelihood of  securing the career (or salary ) that you always wanted. UOP and other campus-based universities have great mba programs designed to give you the education needed to be successful. More importantly  most of these programs allow you to take classes on your own time. No need to fight campus traffic or beg your current employer to work around your class schedule. With online classes, you can complete your coursework where and when you want.

Many persons a background in biology and an MBA are able to secure positions as business analysts, managers, and market analysts for biotechnology companies. Increasingly, they also becoming integral parts of new product development teams that are looking for new medicines and treatments.

According to the U.S. Bureau of Labor Statistics, biotechnology will only increase in need and thousands of jobs will continue to be added each year. To that end, some of the world's largest life sciences companies including Bristol-Myers Squibb and the Bayer Corporation are already seeking MBA students with biological backgrounds.

So if you are looking for a boost in your career, consider getting a MBA or related business degree. While a MBA may not seem like the first choice of a most undergraduate biology student,s it can actually provide the skills and tools needed to succeed in some of the most competitive biological markets today.

Until next time...

Good Luck and Good Job Hunting!!!!!

 

How Online Courses Can Help You Secure a Job

The job market is rough, and many in the field of science, whether they are a chemist or a biologist, are having difficulty obtaining a position. Unless you want a low-paying tech or lab position there isn't much currently available, especially if you don't have an advanced degree. However, many recent college graduates are beginning to find that taking a few online courses can greatly increase their odds of being hired.

For years, online colleges carried poor reputations, but that stigma is rapidly fading. As current professionals are having to obtain additional education on limited schedules, and the internet as a source of knowledge is becoming more trusted, a degree obtained from an accredited online college is now viewed by much of the population as being just as viable as one received from a traditional university.

Employers no longer scowl at online degrees either. In fact, many are beginning to believe that those who obtain degrees online, or those who simply add to their education by taking a few courses, may actually be more valuable than traditionally educated individuals. Seeking additional education online may actually make you more enticing as a job applicant because managing your own education says multiple things about your character.

The Educational Benefit

The main reason why anyone seeks out additional education is to obtain the skill set they need to succeed. By taking online courses you will gain more knowledge of your industry which will make you a more appealing candidate for employers. You will have a more well-rounded understanding of your field, and by taking the classes may secure the additional education needed to look better than another deserving candidate.

The Personal Benefit

Struggling to find a job is no easy task, and at times it can be really rough on your self esteem. By pursuing additional education, you are able to achieve personal goals, and gain greater confidence in your knowledge and abilities. Having both of these attributes will make employers more likely to hire you. Plus, taking the additional courses will keep your mind fresh and will also keep your occupied and focus during your down time.

The Professional Benefit

From an employer's perspective, those who are willing to manage their education on their own are self-starters. They are motivated individuals who now how to set goals and obtain them. Online classes aren't like typical on-campus classes, and require students to remain focused on the tasks at hand. There is no one there to remind them of due dates and constant assignments. Employers know this, and know that anyone capable of getting good grades or a degree from an online university is a driven and organized person, which is what many employers are looking for.

The job market it tough, but your college degree isn't to blame for your lack of employment. Thousands of people have lost their jobs or are struggling to find position all over the United States, and the poor economy isn't helping. The fact of the matter is that the lacking economy has made it hard for anyone to find a job whether they are a biologist like you or a math teacher.

However, all hope is not lost. There are still plenty of well paying positions in the biological field, and you can still find one in one of the various public and private firms that are still hiring. Just keep in mind that there are hundreds of others seeking the same position you are. To get ahead you simply have to be more competitive and make yourself more enticing to employers, and increasing your knowledge by taking online college courses may be the first step in the right direction. 

Until next time...

Good Luck and Good Job Hunting!!!!!!!!!

Jooble: A New Job Search Engine

New job search engines come and go. That said, I was recently contacted by the folks who run Jooble, a job search engine that operates in over 42 countries. While I haven’t used it myself, this is what the company has to say about it.

“Jooble is a vertical job search engine that works in 42+ countries. We continue to expand our job database and each day Jooble has more than 100,000 new job listings

You may use the advanced search in Jooble and enter key words, such as location (city, state), salary ranges, date posted and many other options. Moreover, users can subscribe to our free mailing list which entitles you to daily e-mails delivery of the latest job listings based on keyword searches. This service will improve and accelerate your changes of finding that dream job. Please feel free to subscribe to our mailing list if you wish to get the best and latest job announcements.

Jooble operates in 42+ countries, so if you would like to find a job in other locations you may try to search jobs in: 

Argentina, Australia, Austria, Belgium, Belarus, Brazil, Canada, Chile, Colombia, Czech Republic, Denmark, Spain, Finland, France, Germany, Greece, Hong Kong, Hungary, Italy, India, Indonesia, Ireland, Japan, Kazakhstan, Mexico, Netherlands, Nigeria, Pakistan, Peru, Poland, Portugal, Romania, Russia , South Korea, Sweden, Switzerland, Taiwan, Turkey , Venezuela, Ukraine, United Kingdom, United States

Just Jooble and find your dream job in just few clicks!”

Check it out!

Until next time..

Good Luck and Good Job Hunting!!!!!!!!!

 

A Death Knell For Social Media and Pharma?

For the past few years, I along with many others have advocated the use of social media platforms (mainly Facebook, Twitter and YouTube) by life sciences companies. Despite a very positive beginning by companies like Novo Nordisk, Johnson and Johnson and others, the implementation of social media in the life sciences industry has been stymied by a lack of regulatory guidance by the US Food and Drug Administration (FDA) and legal and commercialization concerns. While many believe that FDA guidance on the topic will be the panacea that they were waiting for, I personally don’t believe that it will make one bit of difference. That said, Steve Woodruff, the author of the IMPACTIVITI Blog, provides one of the best analyses that I have encountered that explains why social media and pharma don’t work well.

In a post entitled “Time to Give Up on Pharma and Social Media,” Steve cogently provides four compelling reasons why it will be difficult for pharma to ever embrace social media for commercial purposes. They include 1) the lack of regulatory guidance; 2) pharma does not communicate or interact in real time; 3) personnel turnover, short term thinking, lack of innovation and too much focus on quarterly profits; and 4) pharma’s addiction to centralized, one-way controlled communications. His bottom line:

Public, interactive, real-time social media platforms and commercial pharma communications simply don’t mesh well 

While I agree with Steve that social media may not be ideal for commercial purposes in the prescription life sciences industry, it may be perfectly well suited for pharmacovigilance and adverse event reporting, clinical trial recruitment and management, education, community outreach and employee recruitment and retention. These are not new ideas. But, because they cost money to implement and don’t contribute the most company’s revenue-driven bottom lines, life sciences companies have not actively explored or embraced them for these purposes. 

Whether big pharma and biotech companies like it or not, social media is here to stay. And, if these companies fail to act soon, they eventually will begin to lose their competitive edges and perhaps more importantly, market share. 

Until next time.. 

Good Luck and Good Job Hunting!!!!!!!!

 

 

The Inside "Poop" On the Life Sciences Industry

I attend this year's BIO meeting in DC and ran into an old friend, Stan Yakatan of Katan Associates.  For those of you who do not know Stan, he has been associated in a variety of capacities within the Life Sciences industry for the past 35 years.

The job titles that he has accrued over his career include CEO, Chairman, Managing Director, Board Member, Investor, Entrepreneur and Mensch!  Hanging out with Stan at life sciences meetings is always interesting, exciting, unpredictable and most often fun!  That said, Stan is a wealth of information about the life sciences industry and I was surprised to learn that he has an invterview video on YouTube!

To that end, I thought it would be interesting to post the interview @BioJobBlog.  Stan's historical and current perspective on the US life sciences industry is interesting to say the least!

 

 

If you want to contact Stan please click here!

Until next time...

Good Luck and Good Job Hunting!!!!!!!

New Thoughts on Pharmacovigilance, Adverse Event Reporting and Social Media

About a year ago, I suggested that real time social media platforms like Twitter could be invaluable tools for adverse event (AE) reporting and related pharmacovigilance activities. However the mere mentioned of the dreaded AE causes many marketing, legal and regulatory affairs professionals at major pharmaceutical companies to break out into a cold sweat. 

As Mark Senak aptly pointed out in a recent post on his blog EyeonFDA,

“...the reporting of adverse events using social media has long been the bogeyman feared by the legal and regulatory departments of drug manufacturers in the US.”

Further, Mark rightly asserts:

“....the adverse event issue may have proven a red herring.  That is perhaps evidenced by the now large number of Twitter feeds that are active representing pharmaceutical manufacturing companies and even their products; the growing, though not as quickly and not with as much success, presence of YouTube channels; the large number of Facebook pages and even an uptick in the number of corporate sponsored blogs – now at five by my count.  If the adverse event reporting issue really were an issue, this presence would be shrinking, not growing.”

So, what is the “real reason” why drug manufacturers refuse to embrace social media like almost every other industry that I can think of? True, FDA has not yet issued its long awaited guidance on the use of social and digital media in the life science industry. But, the lack of guidance has not prevented pharma and biotech companies from innovating in the past. I suspect that one of the reasons why many companies refuse to adopt social media is the requisite transparency and interactivity that are typically associated with its use. And, perhaps more importantly is the perceived loss of control over product messaging that companies with approved drugs on the market have enjoyed for the past 50 years or more.

Whatever the reasons are, I still contend that social media platforms are ideal tools for AE reporting and pharmacovigilance activities. Hopefully, drug makers will come to realize this with or without FDA guidance on the topic.

Until next time...

Good Luck and Good Tweeting!

 

Alternate Career Options: So You Want to Be a Medical Science Liaison (MSL)?

One of the new “hot career” opportunities in the life science industry is something called a medical science liaison or MSL. Increasingly, graduate students and postdocs are beginning to mention MSL as a possible career option. Of course, the first thing that I ask these persons is “Do you know what an MSL is or does on a daily basis?” In most cases, most of these would-be MSLs sheepishly admit that they don’t!

With this in mind, I invited Dr. Samuel Dyer an experienced MSL and CEO and Founder of the Medical Science Liaison Corporation and MSL WORLD to better inform those who may be interested in pursuing a career as an MSL.

What is a Medical Science Liaison?

By Samuel Dyer

The MSL is a therapeutic specialist (e.g. Oncology, Cardiology, Infectious Diseases, Central Nervous System) within pharmaceutical, biotechnology, medical devices, and clinical research organizations (CRO) who has advanced scientific training and generally a "terminal D" degrees in the life sciences (PhD, PharmD, MD).  It's important to note that MSL's are not sales reps and their function is very different.  The primary purpose of the MSL role is to be scientific or disease state experts for internal colleagues (sales and marketing), but more importantly for doctors in the Therapeutic Area of the Medical community in which they work (i.e. Oncology, Cardiology, CNS etc.).  The focus of the role has changed over the years, but the primary responsibility of the MSL role remains to establish and maintain peer-peer relationships with leading doctors, referred to as Key Opinion Leaders (KOL's).

Medical Science Liaison’s (MSLs) were first established by Upjohn pharmaceuticals in 1967 as a response to the need for professionally-trained field staff that would be able to build rapport with Key Opinion Leaders (KOLs) in various therapeutic areas of research. Although originally called Medical Science Liaisons by Upjohn, over the years and today, pharmaceutical companies have used various names for the role including: Medical Liaisons, Medical Managers, Regional Scientific Mangers, Clinical Liaisons, and Scientific Affairs Managers among others.  

Originally, the first MSLs were selected from experienced sales representatives that had strong scientific backgrounds to bring a higher degree of clinical and educational expertise to the medical professionals they were working with to influence sales. Over the years, MSL teams have been made up of individuals with various scientific backgrounds including: “super” sales reps, those with nursing backgrounds, those with various doctoral level degrees or other clinical backgrounds.  However, the required educational and scientific background and purpose of MSL’s has progressively changed over the years since they were first established.  In the late 1980’s, a number of companies began to require those applying to MSL roles to hold a terminal “D” degree such as an MD, PharmD, or PhD degrees.  

Although, historically, the educational standard in the industry did not require MSL’s to have a terminal “D” degree, however, today the terminal “D” degree has become standard in the industry.  Today according to one benchmark study more than 90% of current MSLs hold terminal “D” degrees.  

While the MSL role has received some attention, including a CNN Money article entitled "#1 Job in Pharmaceuticals-10 Jobs for Big Demand-Good Pay”, it remains one of the best kept secrets and one of the most difficult roles to break into.  Few people know about it, and little is written about the role.  In fact, the MSL community is quite small when compared to other professions in the pharmaceutical industry however there has been an explosion in the growth of the position. According to a recent benchmark study, there has been an average growth of 76% of the MSL role since 2005 across the industry in the U.S.

To learn more about the MSL role and find free resources go to www.mslworld.com

Until next time...

Good Luck and Good Job Hunting!!!!!!!!

 

What's Up At Bayer Healthcare?

Several weeks ago Bayer AG’s Chief Executive Officer Marijn Dekkers said that he would consider a “merger of equals” to bolster the company’s sagging healthcare division. The division, a minor revenue source for Bayer AG, posted $25.1 billion in sales last year.

Today, the company announced that by 2013 it would outsource the entire production of its blockbuster MS treatment Betaferon to its German arch rival Boehringer Ingelheim. At present, Betaferon sold in the US is manufactured at Bayer’s production facility in Emeryville, CA. Bayer will close that facility and about 540 jobs will be lost.

Boehringer already manufactures Betaferon sold in Europe and it recently received US Food and Drug Administration approval to also sell it in the US. A Bayer spokesperson said that “It is important for us that we can offer the product from a single source.” While that makes sense from a regulatory standpoint, the decision also suggests that Bayer Healthcare may indeed be positioning itself for sale. It also suggests that Bayer may be abandoning the US market for “greener pastures” in the emerging BRIC markets (Brazil, Russia, India and China).

For more insights into Bayer Healthcare check us this article in Life Science Leader.

Until next time...

Good Luck and Good Job Hunting!!!!!!!

 

The Rumor Mill: Is Cubist Really In Play?

For the past several days, the rumor mill has been rampant with suggestions that UK-based Shire may acquire Cubist, a publicly traded Massachusetts-based biotechnology company that sells Cubicin, an antibiotic indicated for the treatment of certain infections caused by methicillin-resistant Staphylococcus aureus (MRSA).

Rumor has it that Shire approached Cubist about a month ago with a $44.5-a-share proposal ($2.0 billion) and the pair have been in talks about a deal ever since. Last week, Shire announced that it had entered into a deal to acquire private-held Advanced BioHealing for $750 million. Connecticut-based Advanced BioHealing markets and develops products to enhance wound healing and treat diabetic foot infections in patients with diabetes. Shire’s acquisition of both companies would provide it with a substantial US presence in the antibacterial treatment and diabetes markets.

While Cubist may be a good “fit” for Shire, it is not clear whether or not the company will prevail in its takeover bid. Last month, Cubist settled a patent dispute Teva Pharmaceuticals over Cubicin, which lessened the threat of generic competition by the Israeli drug maker. This sparked speculation among a number of Wall Street analysts that other pharmaceutical companies including AstraZeneca and Johnson & Johnson who are themselves facing generic competition, may consider acquiring Cubist in an attempt to add new antibiotics to their antibacterial portfolios. 

This is not the first time that analysts have speculated that Cubicin may be ripe for acquisition. Almost two years ago, word-on-the-street had it that Novartis may acquire the company. Nevertheless, Cubist is one of the few remaining publicly-traded biotechnology companies that specialize in new antibacterial drug discovery. Its potential acquisition by a big pharma company may signal the end of innovative drug discovery in the antibiotics discovery space. Here’s hoping that Cubist remains independent!

Until next time...

Good Luck and Good Job Hunting!!!!!!!!

 

Pharmaceutical Direct-to-Consumer (DTC) Advertising Goes Mobile

While big pharma continues to struggle with the use of social media to promote its products, direct-to-consumer advertising (DTC), the method of choice for American pharmaceutical advertising is alive, well and robust. Therefore, it should come as no surprise that big pharma is reallocating some its traditional DTC advertising dollars to deliver drug ads to mobile devices which are growing in popularity. 

According to a recent article posted on PharmaLive, drug companies are mainly using mobile devices —in addition to delivering ads—to “help educate patients and motivate them to seek, accept, and adhere to therapy.” In other words, to more effectively promote their products to improve sales and corporate profits. Regardless of the motive, medical communication agencies have recognized the trend and have responded by launching mobile divisions and initiatives at their firms. Some agencies are now generating close to 50% of their revenues from mobile initiatives and campaigns. Further, many pharmaceutical companies have finally realized that corporate websites can be more than simple placeholders on the Internet. To that end, the PharmaLive post notes that pharmaceutical brand websites are evolving into a robust resource structured to be easily searchable and maintained. Maybe a better understanding and use of social media is next up for drug makers.

Pfizer remains the leading spender and purveyor of DTC advertising despite a 15% overall decrease in 2010 as compared with 2009. PharmLive reports that the company allocated $903.8 million to brands such as Lipitor, Pristiq, Viagra, Chantix, and Lyrica. Of these brands, Pristiq saw the highest increase of DTC advertising in 2010, up 17% to $122.2 million compared to 2009.

As mobile media continues to grow, don’t be surprised if someone develops a TIVO-like fast forward app to skip all of the DTC ads on your iPhone or android devices.

Until next time..

Good Luck and Good Job Hunting!!!!!

 

An Academic Perspective: Explaining the Current Glut of Life Sciences PhDs

For the past several years, I have been trying to convince anyone who would listen that the reason for the dismal job prospects for most PhD-trained scientists is a simple supply and demand issue. To wit, there are too many PhDs and too few jobs for them! 

While I intuitively understood that this was the case, nobody had ever substantiated the veracity of the claim and consequently I was beginning to think I was wrong. Imagine my joy after reading William Deresiewicz’s piece in this month’s edition of the The Nation magazine. In an article entitled “Faulty Towers: The Crisis in Higher Education,” Deresiewicz elegantly and aptly sums up the situation facing today’s newly minted PhDs:

"At Yale, we were overjoyed if half our graduating students found positions. That’s right—half........You’d think departments would respond to the Somme-like conditions they’re sending out their newly minted PhDs to face by cutting down the size of their graduate programs. If demand drops, supply should drop to meet it. In fact, many departments are doing the opposite, the job market be damned. More important is maintaining the flow of labor to their domestic sweatshops, the pipeline of graduate students who staff discussion sections and teach introductory and service courses like freshman composition and first-year calculus. (Professors also need dissertations to direct, or how would they justify their own existence?)

Further, he asserts:

“......the PhD glut works well for departments at both ends, since it gives them the whip hand when it comes to hiring new professors. Graduate programs occupy a highly unusual, and advantageous, market position: they are both the producers and the consumers of academic labor, but as producers, they have no financial stake in whether their product “sells”—that is, whether their graduates get jobs. Yes, a program’s prestige is related, in part, to its placement rate, but only in relative terms. In a normal industry, if no firm sells more than half of what it produces, then either everyone goes out of business or the industry consolidates. But in academia, if no one does better than 50 percent, then 50 percent is great. Programs have every incentive to keep prices low by maintaining the oversupply.”

Finally he concludes with an eye-opening but sadly accurate observation:

“How professors square their Jekyll-and-Hyde roles in the process—devoted teachers of individual students, co-managers of a system that exploits them as a group—I do not know. Denial, no doubt, along with the rationale that this is just the way it is, so what can you do?”

I am glad that somebody else perceives the problem the way that I do. At least, I now know that I am on the right track! Do any BioJobBlog readers have any suggestions, ideas or insights into how to fix this obviously broken system? 

Let me know!

Until next time...

Good Luck and Good Job Hunting!!!!!!

 

What Exactly Is LinkedIn?

By now, many of you have received an invitation by e-mail to join someone’s LinkedIn network. While some of you may have heard of LinkedIn, you may not exactly be sure what it is and whether or not you ought to accept the invitation to join your colleague’s network. To that end, watching the video below (sponsored by LinkedIn) may help to answer some questions about the network and whether or not it may be right for you.

 

It is becoming increasingly obvious that participation at online social networking at sites like LinkedIn, BioCrowd, Twitter and others are necessary to land jobs in today’s competitive job market. Unfortunately, many scientists are still reluctant to join these networks to help to find jobs or advance their careers. Hopefully, this will change in the future as scientists begin to recognize the career benefits of online networking sites.

BTW, LinkedIn, which has 100 million users* and a presence in over 140 countries, is going public. It latest IPO price was today announced at $45 per share; the top of its expected price range! Other social media companies like GroupOn and Facebook are expected to issue IPOs later this year.

* In a previous iteration of this post, I mistakenly published that LinkedIn had over 200 million members. The actual number is about 100 million....Mea Culpa!

Until next time...

Good Luck and Good Job Hunting!!!!!!

Addendum: LinkedIN successfully completed its IPO on Thursday. After opening at at $83 — up from its I.P.O. price of $45 — and rose as high as $122.70. The shares closed at $94.25, giving the company a market value of roughly $9 billion

 

Pharma and Biotech Job Watch

Merck & Co, which yesterday completed its $430 million acquisition of Inspire Pharmaceuticals, announced that it intends to shut down Inspire’s headquarters in Raleigh, NC. According to a Merck spokesperson closure of the former Inspire site will occur before the end of the year and their will be job losses. However, it is not clear at present how many jobs will be lost but both executive and workforce positions are on the chopping block. 

Inspire was founded at the University of North Carolina, Chapel Hill in1995 and went public in 2000. The company employed 240 workers at the beginning of 2011 but it cut 27 percent of its workforce in February after an experimental treatment for cystic fibrosis failed in clinical trials. Merck’s acquisition of Inspire gives the company AzaSite an approved treatment for pink eye and a treatment for dry that is approved in Japan (the drug failed to gain US regulatory approval).

In other industry news, Connecticut-based Alexion announced that it will add 20,000 sq feet of laboratory and office space to its Smithfield, RI location. The company currently employs 125 workers and plans to expand its workforce by 35 percent in the next year or so. Alexion has one approved prescription medication called Soliris, the only approved therapy for persons with paroxysmal nocturnal hemoglboinuria (PNH) an orphan indication.

Until next time...

Good Luck and Good Job Hunting!!!!!!!

 

The Job Interview Is As Old As Time

I was at the Experimental Biology meeting this year in DC and a career development colleague shared this job interview video with me. As you can see, things have not changed much over the years.  Same questions and answers so be prepared!

Until next time..

Good Luck and Good Interviewing!!!!

On Becoming a Project Manager in the Life Sciences Industry

Project management (PM) is growing as a career option for life scientists. This is mainly because life sciences companies have begun to realize that team projects with professionally trained PMs at the helm (as compared with research scientists lacking in PM skills) are conducted more efficiently and cost effectively.

Because of the “newness” of the PM option, in the life sciences industry, there is no formal training or a direct pathway to become a PM. However, Bruce Fieggen, Vice President of Project Management and Training at QPharma— who has over 25 years of experience as a project manager (and trainer) in the life sciences industry—offers some ideas and insights on how to become a PM.

On Becoming a Project Manager in the Life Sciences Industry

By Bruce Fieggen

By now you have probably worked as a team memberon several projects and may be thinking that a career in project management may be right for you. So, how does one become a project manager in the life sciences industry?

The best first step is to obtain some formal training in project management (PM). There are many courses designed as evening programs, university classes or three day workshops. You can take them in person or online. While some of these training options may not be as comprehensive as others, it will help interested persons to determine whether or not a career in project management may be right for them. Once you have obtained some formal training, the next step is to take an honest look at your personality. Are you an extremely introverted person who feels uncomfortable talking with others on a regular basis? Do you fear speaking in public? Are you a good listener?  

If the answers to these questions are a resounding “no” or maybe, then PM may not be a good career choice. However, if the answers are yes, then volunteer to run a small project or a sub-project of a larger team effort. Be prepared to learn from the mistakes that you undoubtedly you will make. And, also be prepared to do other people’s work in order to get your small project finished on time! Once you have exhibited some aptitude as a PM, you may be asked to take on larger projects and if you are successful you may be on track for a lifelong career as a PM.

People become successful project managers from almost any discipline or field. In my almost 25 years as a PM (and PM trainer), I have seen PMs hail from jobs in R&D, manufacturing, marketing, purchasing, engineering, quality, and regulatory affairs. No particular group produces better PMs than another. That said, all successful PMs:

  • Are great communicators and know how to listen
  • Know the process of managing projects and can show you the schedule, scope and budget at any time
  • Are rarely at the extreme introverted end of the extraversion – introversion continuum
  • Understand how to motivate people to work for them when they don’t actually report to them
  • Implicitly understand that the project (not their egos or kudos that they may receive), takes precedent over everything else

To learn more about a possible career as a PM, I highly recommend that you join PMI.org and attend monthly meetings at a local PMI chapter. Network with fellow PMs and learn from them. Pretty soon you’ll be in the thick of things and understand what being a PM is all about! 

Please check out my Round Table Project Management blog for additional information and feel free to contact me.

Until next time...

Good Luck and Good Job Hunting!!!!!!

 

@AstraZenecaUS Pushes the Pharmaceutical Social Media Envelope

The life sciences industry is all a-Twitter (sorry) about social media and its implications for future business opportunities. Nevertheless, despite the obvious “upside” of social media, as is always the case in the pharmaceutical industry, most companies don’t want to be the first to do anything innovative or novel (go figure).  

Obviously, there are many risks associated with being first in anything. But, the aversion to being first in the industry to “rock the boat” is more pronounced in the pharmaceutical industry than in most others. That said, companies like Novo Nordisk (the first successful promotional product Twitter campaign), Johnson and Johnson ( the first company to blog) and Boehringer Ingelheim (using Twitter for conversational purposes not just a corporate news feed) at various times, dared to go where no company has gone before with the social media experiment. And, despite the apprehension and almost palpable trepidation exhibited by these companies, no overt consequences have resulted from the bold moves made by these social media pioneers. It now appears that there is another new benchmark for companies involved in the pharmaceutical social media experiment; the first ever sponsored pharma Twitter Chat held by @AstraZenecaUS.

This event was first reported (as far as I can tell) by Mark Senak, the author of the informative EyeonFDA blog and one of the leading pharmaceutical social media watchdogs. The Twitter Chat (under the hash tag #rxsave) was held by @AstraZeneca to discuss with its followers ways in which patients can save money on prescription drugs. While I didn’t participate in this somewhat paradoxical chat —a prescription drug companies discussing ways in which patients may save money on their expensive prescription drugs? —it does demonstrate willingness on AstraZeneca’s part to interact with prospective customers in a meaningful way to help them overcome financial barriers to access to potentially life- altering or-saving prescription drugs!

Although there are still no regulatory guidelines governing the use of social media by life sciences companies, the willingness of @AstraZenecaUS to put itself on the line is very refreshing. In my opinion, it is an important first step to help to “humanize” pharmaceutical companies. Also, it demonstrates a willingness by a pharmaceutical company to provide help to persons who perhaps cannot afford or are struggling to gain access to the prescription drugs that they need!

Hat tip and kudos to @AstraZenecaUS!

Until next time...

Good Luck and Good Job Hunting!!!!!!!!

 

Reports of E-Mail Demise May be Greatly Exaggerated

ComScore, a company that tracks Internet traffic recently determined that the number of visitors to Web-based e-mail sites, like Gmail, Yahoo mail and others, declined roughly 5.9 per cent from November 2009 to November 2010. In November, 2009 160 million users used web-based e-mail platforms whereas only 153 million used those services. 

According to comScore, the decline represents the growing use of mobile e-mail devices like Blackberry and the iPhone which don’t require their users to log on to the Web to view messages. However, while the number of people who use mobile devices to check e-mail daily rose to 40 per cent, it isn’t clear whether or not the conclusions drawn by comScore are accurate. For example, I use Yahoo mail daily to check e-mail messages on my iPhone. Moreover, although Web-based e-mail use by persons aged 12 to 17 years dropped 24 percent over the past year, the number of users aged 55 years and older continues to rise. Finally, while my children aged 17, 15 and 12 prefer text and chat to e-mail they all still use web-based e-mail for formal communications with their teachers and older persons. I suspect that this is not very surprising to many BioJobBlog readers because the number of baby boomers (old fogies who are comfortable with e-mail) will continue to overshadow the number of Gen X and Gen Y persons for many years to come. Put simply, we boomers are still in control and will not relinquish it until we all die! And, once, we are gone, things are likely to change.

The point that I am trying to make is that while texting, Twitter and Facebook may be appropriate for informal communication among tweens, teenagers and young adults, e-mail is, and will continue to be, the major means of communication for business purposes. This is mainly because e-mail is much easier to monitor, capture, manage and oversee than texting, Twitter or Facebook. And, perhaps more importantly, unlike the previously mentioned “new” forms of communication, archived e-mail messages are now routinely used in American courts to adjudicate legal disputes that arise between individuals and companies. In other words, e-mail messages are now recognized as being part of the “official record” for legal and business purposes.

Coincidentally, on a college visit last week to a small liberal arts college, our undergraduate guide—a 20-something undergraduate communications and marketing major—quietly shared with me that she doesn’t get the whole Twitter, Facebook and texting “thing.” She said she regularly communicates with college administrators, her professors and most of her classmates via e-mail; mainly because the other forms of communication require immediate attention. And, if you are busy or have work to do or don’t want to talk to someone that can be troublesome. As far as she was concerned, e-mail was the best way to communicate. I am not sure whether or not she said what she did about e-mail for my sake, because during our conversation, she paused for a moment to read a text message from her friend admonishing her that she was late for a lunch date.

Until next time...

Good Luck and Good Job Hunting.

 

BioCrowd Co-Founder, Cliff Mintz, Talks About Building Online Networks for Life Scientists and Physicians

Believe it or not, I was interviewed by Karl Schmieder of Bridge 6, a digital healthcare marketing firm about the genesis of BioCrowd and why online networking is important for bioprofessionals and healthcare providers. This is a first for me and it signals that online networking for life scientists and other bioprofessionals may actually be starting to catch on. You can read the entire interview by clicking here.

While most other sites like Benchfly, Epernicus, Labspaces, ResearchGate and others cater almost exclusively to scientists, BioCrowd was created as an online networking and career development site for ALL bioprofessionals including those involved with marketing, manufacturing, publishing, writing, fun raising etc. We want prospective BioCrowd members to think of the community as a “one-stop-shopping” site for life sciences professionals who want to network, advance a career or even start  up a biotechnology company! Check us out!

Until next time...

Good Luck and Good Job Hunting (I hope to see you at BioCrowd!)

 

Employment Update: Who Is Hiring and Who Is Not!

While US unemployment continues to hover around 9.4 percent, there appears to be a steady increase in the number of companies that are posting ads on job boards like Simply Hired and Indeed.com. According to an article in the NY Times “A Sign of Hope for More Hiring” job postings at Simple Hired roe over 50 percent last year over 2009 and increased almost 70 percent in December 2010 as compared with December 2009.

The situation at Indeed.com, a major competitor of Simply Hired, appears to be similar. That is, there has been a substantial and continual increase in the number companies posting jobs on the Indeed.com website.

However, while this is great news, it isn’t exactly clear what the increased job postings mean. For example, some industries are hiring at a greater rate than others (see below).

Not surprisingly, the greatest increases are occurring in some of the industries that were hit hardest by the recession, e.g. transportation, automotive, legal, manufacturing and financial services. Hiring in healthcare, technology and education remains steady and respectable. On the other hand, two industries that have actually lost ground are media and the military. For a more comprehensive analysis check out the white paper on 2010 Employment Trends created by Simply Hired. Although things look like they may be picking up, the sad reality is that workers who have been unemployed for months have a much harder time landing new jobs as compared with those who have been unemployed for weeks. Unfortunately, many of the workers that make up the 9.4 percent unemployed, have been out of work for six months or more. Further, the availability of jobs will vary by industry and perhaps more importantly geography. Data from Simply Hired suggests that employment opportunities are greater in Washington, D.C, Baltimore, Boston, Milwaukee, Minneapolis/St Paul, San Francisco and Denver as compared with Miami, Detroit, Sacramento and LA. The availability of healthcare jobs appears to be greatest in San Francisco and San Antonio. Interestingly, many of the new job postings are coming from smaller companies rather than those that constitute the Fortune 500 list. This means that former corporate employees may want to focus their job searches on smaller companies rather than continue to seek employment at big name companies.

Despite these encouraging and optimistic signs, the road ahead for most R&D scientists and pharmaceutical sales reps looks pretty bleak. That said, now may be a good time to consider alternate career options or possibly going back to school for retraining. To that end, data from Indeed.com suggests that learning HTML 5, the new, highly anticipated Web development language which may make Flash obsolete, may be the ticket to guaranteed employment. Knowledge of HTML 5 in addition to experience with mobile apps, the Android operating system and Twitter skills that are highly coveted by employers in many industries. Finally, if more school or retraining is not in your future, you may want to consider switching industries, moving to a different type of job in your discipline or, if possible, relocating!

Until next time...

Good Luck and Good Job Hunting!!!!!!!!!

 

Study Finds Pharma Wrongdoing on the Rise

In a first-of-its-kind study, researchers at the Public Citizen’s Health Research Group tracked the civil and criminal financial penalties levied against the pharmaceutical industry for wrongdoing over the past 20 years. 

The main findings of the study revealed:

  1. Of the 165 settlements comprising $19.8 billion in penalties during this 20-year interval, 73 percent of the settlements (121) and 75 percent of the penalties ($14.8 billion) have occurred in just the past five years (2006-2010).
  2. Four companies (GlaxoSmithKline, Pfizer, Eli Lilly, and Schering-Plough) accounted for more than half (53 percent or $10.5 billion) of all financial penalties imposed over the past two decades. These leading violators were among the world’s largest pharmaceutical companies.
  3. The practice of illegal off-label promotion of pharmaceuticals has been responsible for the largest amount of financial penalties levied by the federal government over the past 20 years. This practice can be prosecuted as a criminal offense because of the potential for serious adverse health effects in patients from such activities.
  4. Deliberately overcharging state health programs, mainly Medicaid fraud, has been the most common violation against state governments and is responsible for the largest amount of financial penalties levied by these governments. This type of violation is also the main factor in the considerable increase in state settlements with pharmaceutical companies over time.
  5. Former pharmaceutical company employees and other “whistleblowers” have been instrumental in bringing to light the most egregious violations and have been responsible for initiating the largest number of federal settlements over the past 10 years. From 1991 through 2000, qui tam (whistleblower) cases made up only 9 percent of payouts to the government, but from 2001 through 2010, they comprised 67 percent of total payouts.

The companies, their missteps and the fines imposed are shown below:

The authors conclude:

"Over the past two decades, especially during the past 10 years, there has been a marked increase in both the number of government settlements with pharmaceutical companies and the size of the accompanying financial penalties. Given the relatively small size of current financial penalties when compared to the perpetrating companies’ profits, both increased financial penalties and appropriate criminal prosecution of company leadership may provide a more effective deterrent to unlawful behavior by the pharmaceutical industry."

Interestingly, about a month ago officials at the US Food and Drug Administration signaled that were willing to prosecute company executives to the fullest extent possible (including criminal prosecution) to reduce the incidence of fraud, off-label marketing and manufacturing violations that have become commonplace in the pharmaceutical industry in the past five years.

Until next time....

Good Luck and Good Job Hunting!!!!

Social Media and Pharma: An Update

What a difference six months can make in the fast moving world of the social web! At last May’s Advanced Learning Institute’s conference on “Social Media for Pharma” there was a lot of anxiety, hand wringing and concern about the future of social media in the life sciences industry. 

Things were much different at “Social Media for Pharma” (also sponsored by the Advance Learning Institute) held earlier this week in Manhattan. Like last May’s meeting, there was still much speculation about when the US Food and Drug Administration (FDA) may provide the much awaited regulatory guidance on the use of social media for promotional purposes in the pharmaceutical industry. And, despite a presentation by FDA representatives at the meeting—that somewhat paradoxically described how the agency was using social media tools like Twitter, YouTube and Facebook to better educate and inform the American public about its activities and services —there were no hints about when the agency may issuing that guidance. Nevertheless, the number of pharma and biotechnology companies that have decided to “take the plunge into the social media pool” has grown substantially since last May. In fact, I got the sense that many of the conference participants were beginning to believe that implementing social media strategies was possible even if the agency fails to issue the long awaited guidance!

Generally speaking, there was a growing consensus at the meeting that the use of social media for promotional purposes—specifically to bolster sales of approved and marketed drugs and devices—may not be its best use. Several presentations, most notably those offered by Justin Gardener and Lindsey Hart from Advanced BioHealing, Inc and Jenny Keeney from Astellas Pharma US, Inc showed how social media can be used by life sciences companies to improve healthcare outcomes for patients and promote science education to improve the public understanding of science. Nancy Buono Cartwright from Kaiser Permanente gave a great talk on how to use social media to enhance corporate communication and employee participation and retention. 

A panel discussion featuring Dennis Urbaniak, Sanofi Aventis, Cynthia Phillips, Millennium Pharmaceuticals, Inc and Justin Gardner, Advanced BioHealing, Inc and lead by John Mack aka the Pharma Guy was insightful and extremely illuminating regarding pharma’s changing attitudes toward social media. All of the panelists agreed that the drug industry is in transition and that now may be the time to try new things to get back to addressing unmet medical and patient needs. More importantly, Dennis Urbaniak stressed that pharma must begin to listen to what patients and stakeholders want rather than dictating or imposing “its” ideas and products on them. And, that it is apparent that social media provides an ideal vehicle to accomplish that goal.

Finally, Doug Levy, a compliance lawyer and Executive Director of Communications and Public Affairs Columbia Medical Center, gave an inspiring talk on how social media is no different than traditional modes of communication and that best practices already exist whether or not FDA ever issues any additional guidance on the topic! It appears that it is no longer a question of “if” but “when” as pharma continues to warm to inevitability of social media.

Until next time...

Good Luck and Good Tweeting or Whatever Your SM Tool of Choice May Be

 

Mobile Apps for Life Sciences Researchers

There is no question that mobile apps are de rigueur and like other mobile devices users, life science researchers are beginning to regularly use them! After all, any innovation that can make the long hours spent doing laboratory research, easier, less time-consuming and enjoyable are likely to be welcomed by most researchers.

According to Alex Hodgson, one of the founders of the antibody review site called BioHub Online “mobile apps for science-types are popping up everywhere.” These apps range from lab timers, to mobile notebooks and science journals. 

Alex recently reviewed several mobile science apps on the BioHub Blog  that “piqued her interest” Some of the apps may be familiar to you while others may not. This is what she had to say:

'Bio-Apps: Technology Meets Science'

By Alex Hodgson

Mendeley iPhone App
Free

This application indexes and organizes all of your PDF documents and research papers into your own personal digital library. It gathers document details from your PDFs allowing you to search, organize and cite. It also looks up PubMed, CrossRef, DOIs and other related document details automatically, importing papers quickly and easily from resources such as Google Scholar, ACM, IEEE and many more at the click of a button. 

Sync with Mendeley
Mendeley (Lite) for iPhone syncs seamlessly with your Mendeley research collection. This means that you can now carry your personal digital library with you wherever you go. 

Read your Papers Offline
If there is a paper you want to check out later, you can download it over wifi straight to your iPhone from your online library. It will remain available to read offline at any time, making it easy for you to read what you want, when you want.

Share Citations
If there is a paper that you just need to let your colleagues know about right now, you can share the citation to that paper from within the app via email.

Molecules
Free

Molecules is an application for the iPhone, iPod touch, and now iPad that allows you toview three-dimensional renderings of molecules and manipulate them using your fingers. You can rotate the molecules by moving your finger across the display, zoom in or out by using two-finger pinch gestures, or pan the molecule by moving two fingers across the screen at once. The combination of the iPhone, iPod touch, and iPad's unique multitouch input system and the built-in OpenGL ES 3D graphics capabilities enable you to feel like you are manipulating the molecules themselves with your fingers.

New molecules can be downloaded from the RCSB Protein Data Bank

Primer Jot
$0.99

This molecular biology application aims to help you keep track of your oligos, all in one place, calculate the primer melting temperature (Tm) (based on a standard set of conditions) and categorize it, assign a project, as well as physical location details. Search feature ever allows you to quickly search primers/oligos based on name, project, sequence, Tm and even your notes. A must-have for anyone who works with PCR.

BioLegend Tools for the iPad/iPhone Application
All Free

BioLegend CD Molecules Applications
The application compiles information on all of the Human and Mouse CD Markers based on the findings of the HLDA workshop. Now you can find CD molecule information quickly and conveniently in the palm of your hand.

Cytokines & Chemokines Application
This application provides you with important information about your mouse and human cytokines and chemokines. Now you can find information about cytokines and chemokines quickly and conveniently in the palm of your hand.

BioLegend Tools for the iPad
This application includes information on Human & Mouse CD Molecules from the HLDA Workshop and Cytokines & Chemokines,an Antibody Usage Calculator as well as a lab timer.

Apps from Invitrogen
Free

DailyCalc
Calculate molarity and formula weight, or find unit conversions and cell culture references all with this smart calculator widget.

Alexa Fluor Selection Guide
This handy app serves as a quick reference guide for selecting the perfect Alexa Fluor® dye for your research.

Promega
Free

This application provides lots of great information for life scientists, including quick access to molecular biology calculators, technical tips, protocols, and multimedia presentations. The calculators provide a range of functions essential to molecular biology experiments, including DNA and protein conversions, melting temperature, molarity and dilution calculations.

The Protocols & Applications section of the App covers molecular, cell biology, DNA and protein analysis procedures, and is divided into chapters covering a comprehensive range of topics --from basic amplification techniques to real-time PCR, from simple cell-based assays to complex imaging techniques, and from protein expression to more involved protein interactions assays.

All are available through iTunes

Until next time...

Good Luck and Good Researching!!!!!!!!!!

 

Social Media and Microbiology Education

Vincent Racaniello, a BioCrowd founder and Professor of Microbiology at Columbia University College of Physicians and Surgeons published an article on PLOS Pathogens entitled “Social Media and Microbiology.”

Vincent, a virologist by training, has spent the past 30 years at Columbia where he has been recognized for numerous achievements including identification and characterization of the human polio virus receptor, the creation of transgenic mice to study the neural tropism of the polio virus and the identification of viral virulence factors that contribute to the pathogenesis of a variety of viral infections. His contributions to the field of virology have resulted in a number of honors including the Eli Lilly Award, a Harvey Lectureship, a 10 year Merit Award from NIH and editor of the Journal of Virology and other peer reviewed microbiology journals.

While not conducting laboratory research and teaching virology to undergraduates and graduate students, Vincent spends a considerable amount of time writing for his blog the Virology Blog and creating podcasts for his award winning show entitled TWIV (This Week in Virology). He is a committed educator and firmly believes that his role as a scientist is to improve the public understanding of infectious diseases and science in general. 

The introduction to his article aptly describes his philosophy about social media and science education.

“Social media consists of Internet technologies that allow users to create and share content, and to foster dialogues among other users. Examples include software applications for communication (blogging, social networking, discussion forums), collaboration (wikis, social bookmarking), and multimedia (sharing photographs, video, and livecasting). In the world of science, social media is becoming an increasingly integral component of both research and education. My experience with two types of social media, blogging and podcasting, has convinced me that scientists must embrace these applications to enhance research, and to better communicate their work to the public.”

If you want to learn more about Vincent or chat with him, he can frequently be found at BioCrowd interacting with undergraduates, graduate students, postdocs and even colleagues from time to time.

Until next time...

Good Luck and Good Job Hunting!!!!!!!

 

The BioCon-Pfizer Deal: Pfizer Embraces Biosimilars?

Biocon, one of India’s leading biopharmaceutical companies today announced that they have entered into a strategic global agreement for the worldwide commercialization of Biocon's biosimilar versions of Insulin and Insulin analog products:  Recombinant Human Insulin, Glargine, Aspart and Lispro.  

As part of the deal, Pfizer will have exclusive rights to commercialize these products globally, with certain exceptions, including co-exclusive rights for all of the products with Biocon in Germany, India and Malaysia.  

Biocon will continue to assume responsibility of clinical development, manufacture and regulatory approval of these products in various geographical regions and countries. Biocon's recombinant human insulin formulations are approved in 27 countries in developing markets, and commercialized in 23. Glargine’s first market was India where it was recently launched.  

Under the terms of the agreement, Pfizer will make upfront payments totaling $200 million.  Biocon is also eligible to receive additional development and regulatory milestone payments of up to $150 million and will receive additional payments linked to Pfizer's sales of its four Insulin biosimilar products across global markets.

While both Biocon and Pfizer are pushing the biosimilar aspect of the deal, it is important to point out that recombinant insulin are approved as “drugs” not biologics in the US. Consequently, these products are not true biosimilars and qualify for ANDA approval in the US. That said, it is intriguing that Pfizer is willing to be portrayed as a company that endorses the use of biosimilar medicines. Interestingly, however, there is still no regulatory approval for biosimilars in the US. And, despite public assertions to the contrary, most major pharmaceutical and big biotech companies are fiercely opposed to the introduction of biosimilars to the US. To that end, the current biosimilar legislation recently approved by Congress will prohibit the US introduction of biosimilars until approximately 2020.  

To date, more than 10 biosimilars have received marketing authorization in the EU and other Western markets. Europe approved a regulatory pathway for approval of biosimilars in 2004. Biosimilars have been sold in the so-call gray, unregulated markets in Asia, South America and elsewhere for the past decade.

Until next time...

Good Luck and Good Job Hunting (try India, they are hiring)

 

More Facebook Advice for Jobseekers

There is no question that Facebook is the de facto social network that almost everyone uses. It has become an important source of personal information and is routinely used by professional recruiters and corporate hiring managers to identify right-fit job candidates.

However, there are more nefarious individuals in the ether who may mine your social media data to steal your identity or burglarize your home.

According to Credit.com it is not a good idea to post your address online or your mother’s maiden name (the answer to security questions on many websites). Also the folks at Identify Theft 911 recommend that you don’t add status updates to your Facebook page announcing to the world that you are away from your home or on vacation! Also, they recommend not using applications on social networking sites quizzes, which could expose personal information to the applications’ developer.

Finally, it is not a good idea to mention on Facebook or other social media sites where you were born or security question clues like the names of your favorite song, your best friend or your first pet.

While all of these recommendations may seem obvious, it is very easy to divulge personal information when updating Facebook or tweeting away on Twitter. Unfortunately, there are bad people out there who are willing to exploit others any way they can for financial gain.

Until next time...

Good Luck and Good Tweeting (be careful out there!)

FDA Update: Product Recalls, Social Media and Biosimilar Guidelines

Whether you like President Obama or not, the changes he made in the leadership at the US Food and Drug Administration (FDA) is beginning to yield results. After just two years, the agency is well on its way to modernization and overcoming its descent into the dark ages during the failed Bush Administration.

Mark Senak, the intrepid author of the EyeonFDA blog has been assiduously following and blogging about many of the new things going on at the agency. First, in a post a last week, Mark noted that FDA has updated its website and created a product recall page that collects recall information on all of the products that it regulates and deposited it in an easy to find product recall page. With product recalls in the food and life sciences industry increasing in frequency, this page will help to alert consumers about tainted products before learning of them on the nightly news. 

Second, Mark points out that FDA has finally entered the 21st century and is now fully engaged in social media.

“FDA begins to join the 21st Century launching a Facebook page that has been long anticipated on this blog. FDA has not completed the Social Media Quadrant - (1) a blog, (2) several twitter feeds (3) a YouTube channel, and (4) a Facebook page.  And as added good measure, the agency opened a Flickr page.  The agency is now fully engaged in activities that many in the industry it regulates think is forbidden them.... And the beat goes on.”

Finally, earlier this week FDA announced that it would hold long-awaited public hearings to get input on proposed biosimilar regulatory guidance. As Mark duly notes, this process is likely to be contentious and protracted.    

"The FDA has set November 2-3 for a meeting to get input on a wide span of questions regarding the development of a regulatory pathway for biosimilars.  The scope of the questions is demonstrative of the number of outstanding issues the agency faces and will likely result in a protracted process. "

Central to the debate (and ultimate success of biosimilars) is the question of interchangeability and substitution of name brand products with biosimilar molecules. According to Mark, the agency will focus on the following questions

"What factors should the agency consider in determining whether a proposed interchangeable biological product can be "expected to produce the same clinical result as the reference product in any given patient?"

"What factors should the agency consider in evaluating the potential risk related to alternating or switching between use of the proposed interchangeable biological product and the reference product or among interchangeable biological products?"

What has become patently obvious to many of us who have been following the debate over the last decade is that unless biosimilars are interchangeable or substitutable for brand name biologics, the commercial success of the biosimilar industry may be in serious jeopardy. Put simply, there is no question that safe and effective biosimilars can be manufactured; the real question is whether or not physicians will prescribe biosimilar products if they are required to be branded by regulatory agencies. This is because physicians are reluctant to switch patients to new biologic products if a patient is doing well on a currently prescribed regimen. Since most physicians pay little attention to drug pricing, it is highly unlikely that they will switch a patient to product simply because there may be a 20 percent reduction in drug price. And, unless biosimilar products are deemed interchangeable with their branded counterparts, pharmacists (based on insurance formularies) will not be able to offer patients a generic equivalent of a name brand biologics. 

With the cost of biologic treatments skyrocketing, it will be interesting to see what the agency will do with this question.

Until next time...

Good Luck and Good Job Hunting!!!!!!

 

Suggestions That Can Improve the Quality of Your Resume

I found an article on the Investopedia.com website that provides some useful tips and ideas on how to improve your resume quality and increase the likelihood of a face-to-face job interview.  Some may be obvious while others are not. 

Nevertheless, they are worth reviewing and using if they may sense to you

1. References Upon Request

There is no need to waste valuable resume space on this outdated section. Employers assume that you will provide references if asked. Instead, keep a separate page with the names and contact information of your references ready to supply to the employer once you have advanced in the interview process.

2. One Resume Fits All

While it is smart to keep a master resume on file, you need to customize it to fit each job for which you apply. Job-seekers who take the time to tailor their resume to the employer's needs will stand out from the pack. Eliminate the details that don't apply to the position and emphasize the ones that make you look the most qualified. It might take a little extra time to apply using this technique, but it will be worth it when your interview offers increase.

3. Objective Statement

The professional summary or profile has replaced the objective statement. Employers are focused on what candidates can do for them, not what the business can do for the candidate. You will sell yourself better with a concise bulleted list of the qualifications and accomplishments that make you a match for the position.

4. Single-Page Resume

One of the most touted resume rules is that the document must be one page. Many people will go to extremes to follow this command, resulting in tiny, unreadable font sizes just to avoid having a resume that extends onto the second page.

Unless you are a newcomer to the job market, it is entirely possible that you'll need more than a page to adequately showcase your skills and qualifications. If you have enough job experience that fits the position, it is acceptable to extend your resume length to two pages. Keep your resume succinct and relevant, but don't go under a 10-pt. font size.

5. Lack of Social Networking

Websites such as Facebook and Twitter might be considered distractions in the workplace, but they can be an asset on a resume. Employers want to know that applicants are up-to-date with current technology and communication trends. Links to a professional online portfolio, blog or LinkedIn page should be included in your resume header. There is a good chance that employers will do an internet search to find out more about potential employees, so make sure that all of your social networking profiles project a professional image.

6. Too Much Information

It is not necessary to give your life story on a resume. In fact, providing an employer with too much information can be detrimental to your chances of employment. Delete information about where and when you graduated high school. Ditch irrelevant jobs from 15 years ago. Although it was standard practice in some industries years ago, it is now inappropriate to include personal details in a resume such as information about your hobbies, religion, age and family status. Not only does it look unprofessional, but that information could be used to discriminate against you.

An employer will ask if they want to know why you left previous positions, so don't mention it on your resume. The rule of thumb is to pare down your resume to only include things that show why you are the perfect fit for the specific position for which you are applying.

7. Outdated Terminology and Skills

Skills in obsolete computer software and systems should be removed from your resume. Technical experience is critical in nearly every industry and employers often use technology keywords to find resumes in electronic databases. Listing basic computer skills such as word processing and using an internet browser is not recommended because employers will assume that you have those proficiencies. The job description is the best guide to determine the terminology and technology skills that should show up on your resume.

While I am not totally “down” with the inclusion of social media links on a resume, it’s totally up to you! That said, if you choose to take her advice, I highly recommend that you review all of your online profiles and sanitize them.

Until next time...

Good Luck and Good Job Hunting!!!!!!!

 

A New Wrinkle to Difficult Interviewing Questions

With unemployment high and the economy showing little sign of improvement, finding a new job has become increasingly challenging. And, not surprisingly, the types of interview questions that hiring managers are beginning to ask prospective job candidates are becoming more intricate and complex. I found interesting examples of this at the  “You’re the Boss” blog sponsored by the New York Times.

In the article, a person who owns a small retail business revealed that he always asks job candidates to describe their most stressful customer experience in previous jobs. The question helps him to ascertain how prospective new employees might cope with difficult situations. Also, it tends to reveals whether or not they speak honestly about their own actions and what their attitudes may be towards customers. Another question that he frequently asks is “Why did you really leave your last job? Were you fired? Did you hate your boss? This is devised to determine whether or not a candidate is being truthful. If the answer is their leaving was “mutual” the owner posits that there is usually more to the story than is being divulged. On the other hand, if the response is “It was time to move on” a follow up question usually is “What does that mean?”

Other examples cited in the post include:

What am I going to hate about you in the next 6 months?

What haven’t I asked that you want me to know about you?

How will we both know in six months that you are succeeding?

Why did you apply for this job?

None of the questions is illegal, improper or out of bounds during a job interview. Consequently, I advise jobseekers to add these new questions to their list of difficult-to-answer interview questions. And, perhaps more importantly, think about legitimate responses to them before your next job interview.

Until next time...

Good Luck and Good Job Hunting!!!!!!!

 

Meeting Update: BioConference Live:Clinical Diagnostics

The fourth BioConference Live: Clinical Diagnostics meeting will be taking place on October 20-21, 2010.   This online-only, live, interactive virtual event will cover new technologies, best practices and other pertinent topics for Clinical Diagnostics professionals. Registration is free and all interested persons can attend!  The conference is accredited by the ASCLS American Society for Clinical Laboratory Science and Professional Acknowledgment for Continuing Education (P.A.C.E.).

Therapeutic areas to be covered include: Infectious Diseases, Cancer, Diabetes, Allergy & Immunology, Cardiology, Point of Care, Automation, Molecular Diagnostics, Hematology, Laboratory Testing, Stem Cells, Protein Arrays, and Clinical Chemistry.

Some of the featured speakers include:

  1. Alan Wu Ph.D., Chief of Clinical Chemistry & Toxicology & Prof. Laboratory Medicine, San Francisco General Hospital and University of California, San Francisco
  2. Steven Burrill, CEO Burrill & Company
  3. David Persing M.D. Ph.D., Chief Medical and Technology Officer, Cepheid
  4. Peter Gilligan Ph.D., Professor of Microbiology-Immunology UNC Hospitals
  5. Thomas Goodwin Ph.D., Project Scientist (NxPCM) and Director Disease Modeling & Tissue Analogues Laboratory NASA
  6. Steven Binder, Director Technology Development Bio-Rad Laboratories
  7. Brad Karon M.D., Ph.D., FCAP, FACB, Vice Chair of Education in the Department of Laboratory Medicine Mayo Clinic
  8. Alex Rai Ph.D., Director, Specialty Laboratory, Chief Scientific Officer, Center for Advanced Laboratory Medicine, Columbia University
  9. Robert Fitzgerald Ph.D., Associate Professor, University of California San Diego

Login will take place on October 20th and 21st between 9 AM and 6 PM EST.

Sign Up Now and have a chance to win an iPad if you refer a friend!

Until next time...

Good Luck and Good Learning!!!!!!!!

 

A Guide to Managing Career Change

In this economy, many BioJobBlog readers may find themselves in the unenviable position of having to consider changing careers to find gainful employment. While career counselors like me can offer job seekers ideas about possible alternate or non-traditional careers, actual navigating a career change can be daunting, painful and often times overwhelming. With this in mind, I came across an article on HelpGuide.org that helps to demystify career changes and offers helpful hints (and links to useful articles) that describes how would- be career changers can manage and shepherd the process. 

"Changing Careers: A Guide"

Overview

The first step in considering a career change is to think carefully about what really drives you. You might find it hard to get past thinking about “what pays the most” or “what is most secure,” especially in today’s economy. However, it’s important to first discover your primary interests and passions. This can open doors to careers that you might not have considered. Once you have that foundation, you can start fine tuning your search to the right career. You may be surprised at how you can fit your passions into a certain career!

Explore your options

  • Focus on the things you love to do. What have you dreamed of doing in the past? What do you naturally enjoy doing? Jot down what comes to mind, no matter how improbable it seems.
  • Look for clues everywhere. Take note of projects or topics that stir your compassion or excite your imagination. Reflect on stories of people you admire. Ask yourself why certain activities make you happy, and pay attention to times when you are really enjoying yourself.
  • Be patient. Remember that your search may take some time and you might have to go down a few different roads before finding the right career path. Time and introspection will help you identify the activities you most enjoy and that bring you true satisfaction.

Overcome obstacles to happiness

It’s always challenging to consider a huge change, and there may be many reasons why you may think changing careers is not possible. Here are some common obstacles and how to overcome them:

  • It’s too much work to change careers. Where would I ever begin? Changing careers does require a substantial time investment. However, remember that it does not happen all at once. If you sit down and map out a rough plan of attack, breaking down larger tasks into smaller ones, it is a lot more manageable than you think. And if the payoff is a happier, more successful career, it’s worth it.
  • I’m too old to change careers. I need to stay where I am. If you have worked for a number of years, you may feel that you’ve put too much time and effort into your career to change midstream. Or you may be concerned about retirement and health benefits. However, the more you’ve worked, the more likely you are to have skills you can transfer to a new career. You may also consider planning a transition for after retirement if you are close to receiving a pension or other benefits after a number of years. 
  • I don’t have enough skills to consider a new career. You may be unaware of the skills you have, or underestimate your marketability due to low self esteem. However, you probably have more skills than you think. Consider skills you’ve learned not only from your job but from hobbies, volunteering or other life experiences. And gaining skills is not an all or nothing proposition. You can volunteer once a week or take a night class to move forward, for example, without quitting your current job.
  • In this economy, I’m lucky to have a job. I don’t want to rock the boat. In today’s climate, it might feel like too much of a risk to consider changing careers. However, if you’re unhappy in your current job, doing research on other options will only benefit you in the long run. You may discover a career with a more stable long-term outlook than your current career, for example. And you don’t have to quit your current job until you are confident of your new career path.

Dealing with underemployment and job loss

Being unemployed or underemployed can be tremendously stressful. You may be feeling the pressures of meeting mortgage payments or other financial obligations. You might be feeling ashamed with your family and friends. And a very real loss is that of your identity at work. This is especially true if you have been in the same field for a very long time.

However, unemployment also has a bright side. It gives you the chance to reflect on your career path where you might not have before. If you’ve been considering a new field, now is the time to research and see what might be the right fit for you. You may end up in a much stronger position than if you had originally kept your job.

To learn more, visit Job Loss and Unemployment Stress: Tips for Staying Positive During Your Job Search&

Identify occupations that match your interests

So how do you translate your interests into a new career? With a little research, you may be surprised at the careers that relate to many of the things you love to do. Many online tools can guide you through the process of self-discovery. Questions, quizzes, and temperament sorters can’t tell you what your perfect career would be, but they can help you identify what’s important to you in a career, what you enjoy doing, and where you excel. One example, frequently used by universities and the government, is the RIASEC/Holland interest scale. It identifies six common areas that people often feel especially drawn to, such as investigative, social, or artistic. Based on these areas, you can browse sample careers that match those interests.

The Career Decision-Making Tool

The Career Interests Game

The Motivated Skills Test

The Career Values Test

Research specific careers

If you have narrowed down some specific jobs or careers, you can find a wealth of information online, from description of positions to average salaries to estimated future growth. This will also help you figure out the practical priorities: How stable is the field you are considering? Are you comfortable with the amount of risk? Is the salary range acceptable to you? What about commute distances? Will you have to relocate for training or a new job? Will the new job affect your family?

Occupational Outlook Handbook (US Department of Labor)

Career Guide to Industries (US Department of Labor)

Best Careers (US News and World Report)

Get support and information from others

While you can glean a lot of information from research and quizzes, there’s no substitute for information from someone currently working in your chosen career. Talking to someone in the field gives you a real sense of what type of work you will actually be doing and if it meets your expectations.  What’s more, you will start to build connections in your new career area, helping you land a job in the future. Does approaching others like this seem intimidating? It doesn’t have to be. Networking and informational interviewing are important skills that can greatly further your career.

You may also consider career counseling or a job coach, especially if you are considering a major career shift. Sometimes impartial advice from others can open up possibilities you hadn’t considered.

Evaluate your strengths and skills

Once you have a general idea of your career path, take some time to figure out what skills you have and what skills you need. Remember, you’re not completely starting from scratch—you already have some skills to start. These skills are called transferable skills, and they can be applied to almost any field. Some examples include:

  • management and leadership experience
  • communication (both written and oral)
  • research and program planning
  • public speaking
  • conflict resolution and mediation
  • managing your time effectively
  • computer literacy
  • foreign language fluency

Identify transferable career skills

  • Don’t limit yourself to experiences only at work. When you are thinking about your skills, consider all types of activities including volunteering, hobbies and life experiences. For example, even if you don’t have formal leadership or program planning experience, founding a book club or organizing a toy drive are ways that you have been putting these skills into practice.
  • List your accomplishments that might fit in. Don’t worry about formatting these skills for a resume at this point. You just want to start thinking about what skills you have. It can be a tremendous confidence booster to realize all of the skills you’ve developed.
  • Brainstorm with trusted friends, colleagues or mentors. They might remind you of transferable skills you might have forgotten, and help you think of how you might want to articulate these skills in the future.
  • Learn more about your qualifications. Take the free online Transferable Skills Survey.

Develop new skills and acquire work experience

If your chosen career requires skills or experience you lack, don’t despair. There are many ways to gain needed skills.  While learning, you’ll also have an opportunity to find out whether or not you truly enjoy your chosen career and also make connections that could lead to your dream job.

  • Utilize your current position. Look for on-the-job training or opportunities to do projects that develop new skills. See if your employer will pay part of your tuition costs.
  • Identify resources in the community. Find out about programs in your community. Community colleges or libraries often offer low cost opportunities to strengthen skills such as computers, basic accounting, or how to start a business. Local Chambers of Commerce, Small Business Administrations, or state job development programs also are excellent resources.
  • Volunteer or work as an intern. Some career skills can be acquired by volunteering or doing an internship. This has the added benefit of getting you in contact with people in your chosen field. Visit Volunteering and its Surprising Benefits: Helping  Yourself while Helping Others
  • Take classes. Some fields require specific education or skills, such as an educational degree or specific training.  Don’t automatically rule out more education as impossible. Many fields have accelerated programs if you already have some education, or you may be able to do night classes or part-time schooling so that you can continue to work. Some companies even offer tuition reimbursements if you stay at the company after you finish your education.
  • Consider starting your own business If you’re getting worn down by long commutes or a difficult boss, the thought of being your own boss can be very appealing. And it may be you can find your perfect niche even in a slower economy. Depending on the specialty, some companies prefer to streamline their ranks and work with outside vendors. However, it is especially important to do your homework and understand the realities of business ownership before you jump in.

Make sure you are committed and passionate to your business idea. You  will be spending many long hours getting started, and it may take a while for your  business to pay off.

Research is critical. Take some time to analyze your area of interest. Are you filling an unmet need? Especially if you are considering an online business, how likely is your area to be outsourced? What is your business plan, and who are your potential investors? Learn more in the resources section below.

Expect limited or no earnings to start. Especially in the first few months, you are building your base and may have start up costs that offset any profit initially. Make sure you have a plan on how you will get through that time.

Final thoughts             

  • Pace yourself and don’t take on too much at once. Career change doesn’t happen overnight, and it is easy to get overwhelmed with all the steps to successfully change careers. However, you will get there with commitment and motivation. Break down large goals into smaller ones, and try to accomplish at least one small thing a day to keep the momentum going.
  • Don’t rush into a change because of unhappiness in your current job. If you are stressed and unhappy in your current job, or unemployed, you might be feeling a lot of pressure to make a quick change. However, if you don’t do enough research, you might end up in an even worse position than before, with the added stress of a new position and new learning curve.
  • Ease slowly into your new career. Take time to network, volunteer and even work part time in your new field before committing fully. It will not only be an easier transition, but you will have time to ensure you are on the right path and make any necessary changes before you are working full time in your new field.
  • Take care of yourself. You might be feeling so busy with the career transition that you barely have time to sleep or eat. However, managing stress, eating right, and taking time for sleep, exercise and especially loved ones will ensure you have the stamina for the big changes ahead.

 

 Related Career Change Links

Overcoming obstacles

Taking the Fear Out of Career Change – Provides specific action steps to common fears in considering a career change. (University of Minnesota Office of Human Resources)

How Fear Can Stop a Career Change – Outlines five main stumbling points to considering a new career, and how to move past them. (Suite101, commercial site)

Career investigation resources

Best Careers- US News and World Report – Provides updated information on good careers based on future outlooks and job satisfaction, as well as future trends and jobs that may be overrated. (US News and World Report, commercial site)

Occupational Outlook Handbook – Provides information on different careers/occupations, including what workers do on the job, working conditions, training and education needed, earnings and job prospects. (US Department of Labor)

Career Guide to Industries – Provides information on careers available by industry groupings. Also gives outlook on industry, overall earnings and training information. (US Department of Labor)

Job Hunters Bible  – Gives web resources and advice from Richard Nelson Bolles,’ author of What Color is Your Parachute?, on finding the right job or career, including tests and advice, research, making contacts, finding a job, and creating a resume. (JobHuntersBible, commercial site)

Career tests

Career Decision Making Tool – A comprehensive tool that walks you through defining career interests, from identifying key areas of interest using RIASEC codes to finding the careers that match those interests. (America’s Career Resource Network)

The Meyers Briggs Temperament Indicator II  – Offers a short Meyers Briggs exam to assess your temperament. Answer all the questions for a 4-letter personality indicator and an explanatory document. Registration required. (Advisor Team, commercial site)

Queendom – Offers a collection of tests and resources designed to help you along your path of self-discovery. (Queendom, commercial site)

Evaluating transferable skills

Transferable Skills (PDF) – Provides an overview of transferable skills most desirable for employers, and how you can apply your experiences to those areas. (USC Career Planning and Placement Center)

Transferable Skills Survey - A survey to help you zero in on your transferable skills. Rate your skills in five broad transferable skill areas. (University of Minnesota Duluth Knowledge Management Center)

Career counseling, education and job placement support

Employment & Training Administration – Information about federal job training programs and a section of the site, Regions & States, lists state and local employment resources for all states and regions. Also has a function to search the Fastest Growing Occupations by State. (US Department of Labor)

Jobs for the Future – Nonprofit organization that helps young people and undereducated adults get the training and education they need to get jobs. (Jobs for the Future)

The Women's Alliance - Organization of community-based members who provide professional attire, career skills training and related services to low-income women seeking employment. (The Women's Alliance)

Starting your own business

How to start your own business and maintain your sanity – Learn about the pros and cons about starting your own business including entrepreneurship in a slow economy, what to expect with investors and managing slow beginnings. (US News & World Report)

Starting a business – Provides step by step information on what you should consider when starting a business, including necessary licenses and permits, state and federal requirements, and pros and cons of incorporation (Nolo)

Tips for career changers

Career Changers: Make the Job Market Care – Tips on changing your perspective on careers and how to reduce frustrations and anger during your job search. (Psychology Today)

The 10 step plan to career change – Provides a checklist of areas to review in changing careers, including special sections for seniors, women and minorities.

Until next time...

Good Luck and Good Job Hunting!!!!!!!

 

Good News for Jobseekers: German Law Will Limit Employer Use of Facebook to Vet Job Candidates

Over 70 percent of hiring managers and HR professionals routinely use Google to find out more about prospective job candidates. While many jobseekers know this and do everything possible to expunge deleterious and compromising information from a Google search on their names, some don’t know that Facebook profiles are a routine target of all Google searches. Consequently, hiring managers may have access to some personal information (including photos) that may jeopardize a job candidate’s prospects.  

Today, German government officials proposed a new law that would place restrictions on employers who want to use Facebook profiles to recruit and vet job candidates. The bill would allow hiring managers to search for publicly accessible information about prospective employees on the Web and to view pages on job networking sites like LinkedIn, BioCrowd and Xing.  But it would not allow employers to access or use information about job candidates on purely social networks like Facebook. The proposed law would also prohibit companies from secretly videotaping employees except in certain areas as long as they disclosed the fact.

The idea of crafting legislation to limit company access to personal information of job candidates found on social networks like Facebook, Ning and others reveals the underlying paradox of the social media phenomenon. That is that people publicly, voluntarily and willingly offer private and intimate information about themselves as part of their right to freedom of expression and then that information can be used against them! In other words, the transparency and inherent freedom of expression offered by social media can in reality hinder, restrict or inhibit the professional and social opportunities of those who use it. I highly doubt that legislation similar to the proposed German law would ever see the light of day in the US.

For now, I highly recommend that jobseekers continue to routinely Google themselves to see what information is “out there” about them. Also, continue to limit access to personal profiles on Facebook and any other “purely social” online networking sites that you may belong too. Both activities will help to insure that the photo of you in a compromising position or with a beer bong in your hand won’t eliminate you as a prospective job candidate.

Until next time....

Good Luck and Good Job Hunting!!!!!!!!

 

Words of Wisdom from the Executive Suite

For the past few years, CEOs have been taking a lot of heat; and in many cases rightfully so. However, from time to time some of these “captains of industry” say things that may be useful to ambitious young executives, employees and would-be entrepreneurs. 

The folks over at BestCollegesOnline sent me a link to a post entitled “The 30 Best CEO Interviews You Should Watch on YouTube.” While I haven’t seen any of the videos (I don’t have the luxury of time to do so), viewing some of them may be worth it!

Check them out and let me know if find a good one.

Until next time...

Good Luck and Good Job Hunting!!!!!!!!!

 

After a Lull, Pharma Job Cuts Rise Again

According to a post today on the Pharmalot Blog,

“After what appeared to be a slowdown in layoffs taking place in the pharmaceutical industry, job cuts are accelerating again, according to the latest monthly tally from Challenger, Gray & Christmas. There were 2,023 jobs lost in pharma in July, a notable uptick from the 830 lost in June. Overall, the industry has shed 37,010 jobs this year. “

While I think the massive layoffs that occurred in past three years are unlikely in the future, pharma companies will continue to downsize as patent expiry of blockbusters continue and M&A activity in the biotechnology sector rises.

Until next time,

Good Luck and Good Job Hunting!!!

 

Beware of Job Title Inflation

Although the economy is in the toilet and unemployment remains high, highly skilled and ambitious employees are usually not at risk of losing their jobs. In fact, these employees are highly sought after and frequently contacted by recruiters trying to get them to “jump ship.” In other words, there will always be jobs for these employees even though the rest of us may be unemployed. Companies clearly recognize the value of these employees and will use all available strategies to retain them. 

During good economic times, this usually means a promotion and a concomitant salary increase. However, during recessionary times companies tend to promote these “good” employees into position with greater authority without a pay raise: the assumption being that tacking on a fancy new job title with some added responsibilities will be sufficient to stroke an employee’s ego and ignore the lack of additional compensation for a larger workload. 

To that end, the folks over at the online masters degree website recently posted an article entitled Job Title Stuffing 101: 12 Buzzwords to Inflate a Job’s Importance. It is a veritable tutorial on inflated job titles and the one that you ought to avoid (see below) if possible.

1. Manager: This title may be given to anyone and everyone who ever heads up a project or department, no matter how large or small. It’s used to give slight leverage to the person in charge of the task at hand, but can mean little to the project manager’s supervisors. Because many companies push team creativity, the manager is primarily responsible for turning things in and will be the one to hear about if the boss isn’t satisfied

2. Strategist: A strategist of any type simply means you plan tasks and have some idea of how these tasks are most efficiently executed. For example, in the case of a content strategist, it means you create and organize the content of a newsletter, website, or blog. Is the job important? Sure. But for some reason content strategist sounds a lot more impressive than web editor. You take your pick, but if the former is going on your resume, you better deliver.

3. Deputy: In the age of the Internet, there’s a deputy for many jobs. What does this mean? Well, it means you aren’t quite a junior or an assistant, but the company doesn’t have the funds to pay you like they would someone with the actual title. An example is an editor-in-chief versus a deputy editor. One issuse that you may run into being a deputy of any sort is more on your plate than you bargained for. But you’re the deputy, so you can handle it, right?

4. Senior: Companies love to tack this one onto a title. Senior web writer or senior designers are common for firms. What does this senior title translate to? Anyone with 5+ years of experience in a field and still utilizing those skills can serve as a senior, usually without the pay or responsibilities of management. Simply put – you do your job well, but the buck stops here.

5. Producer: This one has become popular for the web. Web producer pops up on many mainstream blogs and sites. A producer can wear many hats, and for a company that means more bang for their buck. Sure, you will be producing content, but expect handling anything the project throws your way even if it isn’t in the job description (and there’s a solid chance it won’t be)..

6. Supervisor: Like managers, this title can be hit or miss. For large corporations that have had to cut back and eliminate lower level management, pawning the title of supervisor off on an entry level employee who’s been in their cubicle for six months means having someone in the office to make sure things run well without having to douse them in a raise. There are some supervisors who are able to oversee a small department, but ultimately are not the first in command for their subordinates.

7. Ambassador: This job title buzzword is almost an insult to the actual word! In the age of promoting, you know, everything, the job title of brand ambassador is given to celebrities in a niche group that endorse the product sometimes without appearing in ads. This person is contracted by the company or simply receives perks and free services from the brand. They often do little more than show up at launch parties and events and plugs the company as needed. For Channel, The Misshapes Leigh Lazar serves as a brand ambassador and for AT&T, there’s Internet has-been Justine. The problem with brand ambassadors is often large corporations are the last to discover the new face of a niche audience.

8. Professional: A friend says that anytime you have to tack the word professional onto your job title, you must not have a real job. This is up for debate, but let’s take a look at a couple of titles that utilize the word. How about professional organizer? Or records distribution professional? By the way, the latter is the new uppity name for mail room clerk. Yes, even those fresh out of college need an inflated job title. Professional used to mean you had proper training for whatever you do, now it means you are paid some type of wage for what you do, no matter how little that is or the responsibility it entails.

9. Consultant: Who knows what you do with this title. It can mean you directly fix problems, as in the case of IT consultants or it can mean you merely offer your advice, in the case of interior design consultants. Many consultants bring in the big bucks and are contracted by major corporations, but many others work for themselves and struggle to get by. While this title isn’t necessarily inflated, it doesn’t really give the total picture of what you’re hired to do either (which you may prefer).

10. Vice President: Somewhere in the past decade, a lot more vice presidents have shown up to the company picnic. Instead of having a manager of ____, that job became VP of Public Relations or VP of Human Resources. It means second-in-command, in that department and not much more. There used to be only one

VP per company, but we’re guessing the more, the merrier, even if it is job title inflation in its boldest form.

11. Global: Even a mom-and-pop shop can have a Global Director of Communications. It can be mom, working from the family’s dry cleaning business to update the company’s Twitter and Facebook pages. Many companies are employing social media personnel and since a lot of these companies indeed do business around the world, why not stick the word global onto the job title of someone who represents your business to the world? It makes the job sound more exciting and may get you onto someone’s Follow Friday!

12. Lead: The word lead in a job title can mean a lot or a little. In some cases, it means you are heading up an operation, but in most cases it means the company is utilizing you for your skills and maximum potential without proper pay. Some companies use this title as a stepping stone between entry level and a lower management position to see if someone is ready for the next tier of responsibilities.

While promotion without compensation is not novel, it is rampant in today’s uncertain economic times. A word of advice: if you are being considered for a promotion, the first thing that I would ask is whether or not the promotion comes with a pay increase. If not, you ought to think twice about accepting the promotion and call the recruiters back who are trying to lure you away to a competitor’s company. Accepting a position with increased responsibility without a pay raise sends a signal to management that you can be exploited and taken advantage of. And, management will likely continue to exploit you until you call that recruiter back who tells you that a person with your title and level of responsibility can earn much more at a competitor company! That begs the question: Is job title inflation without compensation really a good way to promote employee retention? I think not!

Hat tip to onlinemastersdegree.org

Until next time...

Good Luck and Good Job Hunting!!!!!!!!

 

The Job Search: What Executives and Hiring Managers Are Looking for in Job Candidates

There is no question that interviewing is an art and that experienced job candidates may have a leg up on more junior candidates seekers when it comes to face-to-face (F2F) job interviews. That said, there is a commonly held belief among job seekers that hiring managers frequently ask silly, “bonehead” and irrelevant questions during F2F interviews. Examples of these frequently asked questions include “What are your strengths and weaknesses” and “Tell me how you overcame adversity or a difficult situation at work.” 

During a talk that I give on interviewing tips and insights, I usually make light of these and related questions and warn would be job seekers to be prepared for them during F2F job interviews. However, while I poke fun at these seemingly silly questions, responses to them are growing in importance in decision to determine whether or not to extend offers to job candidates. This is because during recessionary times employers have to be more judicious about the qualifications, skills and personalities of the persons that they hire. After all, jobs are few and far between at most companies and hiring managers want to insure that they derive the maximum benefit from all new hires. 

A good example of what goes into hiring decisions these days can be found in an article entitled “Hearing the Right Notes From a Job Candidate" written by Carl Diehl a co-owner of a franchised exercise company. In the article, he describes the interviewing and hiring criteria that he used to hire a person into an entry level position at his company. Much to my surprise the final hiring decision almost exclusively hinged on the response to the question “What do you consider to be the dark side or major weakness of your personality?” As Mr. Diehl aptly stated:

This type [of question] focuses on performance and accomplishing tasks, but can be oblivious to the emotional needs of themselves and others. Obviously, an awareness of this kind of flaw is very significant in business as well as in personal relationships.

Most of the applicants did not have a clue about what I was looking for when I asked about that “dark side.” The two finalists, however, told me that while people with this personality type might be very hard-working and results-oriented, they could also be unaware of the effects of their actions and words on other people. That demonstrated the kind of emotional maturity I was seeking.

Also high on his list were, energy, creativity and problem solving skills. I highly recommend those of you who are actively seeking employment to read the article. It will definitely help in your job search and prepare for your next F2F job interview.

Until next time...

Good Luck and Good Job Hunting!!!!!

 

A New Job Search Tool is Added at BioJobBlog

Some of you may have noticed that a new tab entitled “BioCareers” has been added to the BioJobBlog navigation bar.  If you click on the tab you will be taken to the BioCareers a new  job board and search engine agent created by Career Management Source and BioCrowd

BioCareers offers real time job listings, application tracking, and e-mail job alerts. Employers can post jobs, advertise jobs, search resume databases and have jobs listed on other jobs like Job Job-Job Health and Twitter jobs. 

The search engine that powers BioCareers automatically pulls life sciences jobs in real time and updates job searches when positions are filled or new ones become available. Candidates can search for jobs by location or job title. One of the nicer features of BioCareers is candidate e-mail alerts that are automatically generated when new jobs are posted or added in real time by the search engine.

To check out BioCareers click on the BioCareers tab or here.  We are in beta right now; so let me know what you think!

Until next time...

Good Luck and Good Job Hunting!!!!!!!

 

Job Cuts Slow But Continue at Pharma and Biotech Companies

There are signs that the economy is improving and that unemployment levels have dropped from a high of 10.1 % to current levels which are hovering around 9.5 %. While this is good news, job cuts continue at many pharmaceutical and biotechnology companies as drug candidates fail in clinical trials and technological advances make certain employees dispensable.

Yesterday, Johnson and Johnson announced that it would layoff 300 of 400 employees who work at the Fort Washington, PA plant that was responsible for the recent Tylenol brouhaha and recall. According to a post on the Pharmalot blog:

”The employees are being let go because it is not clear when the plant will operate again. A J&J spokeswoman says the “best estimate” is the middle of 2011. It isn’t clear at this point whether or not any McNeil executives who oversaw operations at the troubled facility will also be shown the door."

In other news, Adolor, a Pennsylvania-based specialty drug maker, announced yesterday that it was laying off 30 workers or 30 per cent of its workforce to preserve capital and advance its opioid bowel dysfunction clinical development program through proof-of-concept studies in 2011. Also on Friday, the company stated in a press release that two new drug candidates it was developing with Pfizer to treat pain caused by osteoarthritis did not work better than a placebo in a Phase II clinical trial involving 400 patients. The company has one drug on the market, Entereg, a treatment that helps restore bowel function in adults who have undergone bowel re-section surgery. Earlier in the week, GlaxoSmithKline, which co-developed Entereg, scaled back its relationship with Adolor.

Finally, Eli Lilly & Co told its employees that it plans to cut 340 information technology jobs in 2010. Most of the cuts will take place in Indiana (Lilly’s corporate headquarters is in Indianapolis). The company has 1,350 information technology employees nationally. Earlier this year, Lilly has said it will eliminate 5,500 jobs by the end of 2011 to save $1 billion.

Until next time...

Good Luck and Good Job Hunting!!!!!!

 

The Job Search: Appropriate Interviewing Behavior

Congratulations! The resume that you spent many hours carefully crafting has resulted in a face-to-face interview at a Company that you are extremely interested in. After the adrenalin rush has worn off, you think “OMG, I have to put together a seminar, make travel arrangements and buy new clothes and shoes (well only if you are a woman)”. Although you may think that the hard part of your job search is over; think again….the fun is just beginning.

The fact that you been invited to a face-to-face interview means that you likely possess the knowledge and technical skills required to performed the job that was advertised. The true intent of a face-to-face interview is to determine whether a job candidate has the personality and so called “soft skills” to easily fit in with a company’s corporate culture. Corporate cultures and soft skill expectations vary widely from company to company. That said, it is important to remember that certain types of behavior are expected of ALL job candidates during a face-to-face interview. I discuss a few of these expected behaviors below.

First, regardless of the state of affairs in your personal or professional life, you must always be upbeat and positive. Every person you meet should be greeted with a smile and a comment that goes something like “It is a pleasure to meet you”. Nobody wants to talk with (or possibly work with) a chronically unhappy or negative person. True, there ought to be diversity in the workplace (unhappy people have rights too) but when it comes to a positive attitude it is a requirement in the corporate world. Second, always make eye contact with your interviewers. We are social creatures and not making eye contact may signal to the interviewer that you are either anti-social or lack basic interpersonal communication skills. Further, never interrupt an interviewer when they are asking you a question. Yes, everyone gets excited and wants to show the interviewer how smart they are, but cutting a person off in mid-sentence is not polite nor is it ever appreciated by the person who is talking. Always answer questions directly and honestly. Never exaggerate or stretch the truth (as appealing as it may seem in the moment)….it will likely come back to haunt you in future. Also, do not offer the interviewer more information than is necessary. For example, an interviewer may say “I see that you did your postdoctoral work with Dr. Doolittle at MIT”. An appropriate response to this statement could be something like “Yes, he/she was my supervisor during my 8 years in the lab. An inappropriate response may go something like “Yes I worked with Dr. Doolittle for 8 years and, I have to tell you, it was the worst 8 years of my life because Dr. Doolittle is nuts”. Although Dr Doolittle may actually be nuts, you do not know what the interviewer’s opinion of Dr. Doolittle is and, for all you know, they could be best friends. Which leads me to my next recommendation– never play the name game. What I mean by the name game is illustrated in the following example. An interviewer asks you, “BTW, did you ever work with Dr. Spock while you were working for Dr. Doolittle at MIT?” If you did in fact work with Dr. Spock, an appropriate response may be “Yes, I worked with Dr. Spock on several occasions.” It is never a good idea to share your actual experiences or true feelings (positive or negative) about a person with the interviewer. This is because you do not know what the relationship is between the interviewer and the person whose name was mentioned. In the example with Dr. Spock, it may be that Dr. Spock slept with the interviewer’s spouse (stranger things have happened) a few years ago and saying anything remotely positive about Dr. Spock, in this instance, is highly unlikely to garner you a job offer.

Frequently, candidates either go out to lunch or dinner with company employees who are hosting the interviewing visit. Just because you are no longer talking with these folks onsite, don’t think that you can relax, kick off your shoes and let your hair down. Contrary to popular belief, you are still being carefully scrutinized and evaluated for your social skills and how you might represent the company (if hired) in social situations. That said, follow the lead of your host(s). If he/she orders an alcoholic beverage, then it is perfectly acceptable for you to also order a drink. However, if you tend to “loosen up” after a few drinks (remember; loss lips sink ships) it may be wise to limit or not drink alcohol during the meal. Finally, and surprisingly perhaps most importantly, remember to turn off all electronic devices before you step in the building to begin your interview. In fact, you may want to leave your cell phone in your rental car or briefcase (turned off ) for the entire interview. A ringing cell phone during an interview is a definite “job killer”.

Until next time…..

Good Luck and Good Job Hunting!!!!!!!!

 

The Job Search:The Art of Resume Writing

One of the many things that I was not taught in graduate school (or as a postdoctoral fellow for that matter), was how to prepare a resume. Despite opinions to the contrary, a resume is a very important document that must be well organized and carefully crafted. This is because the first thing that every hiring manager sees when looking for new employees is a job applicant's resume. As the old adage goes, first impressions are the most important and the ones that last the longest. That said, it is typically in a job candidate's best interest to have the first impression be a good one. To that end, resume should not be prepared hastily nor should theybe crafted without a substantial amount of thought and consideration. I do not want to get into the nuts and bolts of resume writing in this post. However, every resume should contain the following information:

  • Contact information including name, phone number and e-mail address (mailing addresses are optional)
  • A summary of qualifications that concisely represents your skill sets and talent that you want a prospective employer to know about
  • Chronological listing of your professional experiences to date and an accompanying description of your accomplishments at each position
  • Education including undergraduate, graduate or certificate credentials (dates obtained are optional)
  • Awards and honors
  • Membership in any societies or relevant organizations
  • Any special skills or talents you may possess, e.g. website design, underwater basket weaving, etc.
  • Publications (abstracts and presentations are optional)
  • In general, references should not be included on a resume (if an employer asks for them, send them under separate cover or simply place them on the resume sent to that employer)

As scientists, we are trained to believe that personal achievements will be recognized and that promoting or marketing oneself is a "no-no". However, in the real world, self promotion and aggressive, shameless self marketing is what enables most individuals to get jobs and embark on successful careers. With this in mind, a well organized and carefully crafted resume is one of the most powerful marketing tools at your disposal! As we say in the recruiting biz, a resume will get you in the door......after that, it is up to you to "sell" yourself. 

Until next time...

Good Luck and Good Job Hunting

The Job Search: Transcending the Transition from Academia to the Real World

The ever-increasing competition for faculty positions is forcing many graduate students and postdocs to consider careers outside of academia with a likely eye on industrial jobs. Unfortunately, many of these would be industrial scientists lack the appropriate training and qualifications for entry-level jobs at pharmaceutical and biotechnology companies. This is because most undergraduate and graduate programs do not offer training to their students in drug development, quality systems and manufacturing. The reasons for this include: 1) lack of well informed and qualified faculty members to initiate and develop specialized curricula on these topics and 2) a belief that job training is the responsibility of prospective employers, not academic researchers. Unless substantive curricular change is made to existing academic programs, the road to employment for many students will continue to be bumpy and fraught with difficulty. 

In contrast with academic research, industrial research is highly regulated and guided by legally-enforceable rules and regulations, e.g., Current Good Laboratory Practices (cGLP), Current Good Clinical Practices (cGCP) and Current Good Manufacturing Practices (cGMP). These rules and guidelines were created by regulatory agencies like the U.S. Food and Drug Administration (FDA) to ensure the development of safe and efficacious products. In recent years, the FDA has begun to enforce these rules and regulations more strictly. As a result, many life sciences companies now require that prospective employees understand cGLP, cGCP and cGMP guidelines and how to apply them in industrial laboratory settings. Because these rules and regulations are specific to industry and relatively unknown in academia, most academically-trained job candidates fail to qualify for these industrial jobs. Finally, over the past five years, there has been a growing emphasize on the importance of so-called "soft skills" e.g., good oral written and communication skills, teamwork, professional behavior, etc. in existing and prospective employees. These skills are increasingly important as life sciences companies grow larger, more diverse, and increasingly multidisciplinary in their approach to drug discovery and development. Unfortunately, few academic programs develop these skills in a systematic way; this failure hinders the ability of students to obtain industrial jobs.

Although the transition from academia to industry can be difficult, students can do several things to improve their odds. First, take advantage of available resources in preparing your resume and learning how to interview for an industrial position. A well written, carefully crafted resume can result in an interview, and a professional interviewing style can increase the likelihood of a job offer. Working with a skilled and well-connected professional recruiter may also increase the probability of securing an industrial job.

Second, many community colleges and several companies now offer specialized training in quality systems, regulatory affairs (cGLP, cGMP and cGCP) and other areas. Finally, there is no better way to get an industrial job than to have previous industrial experience. To get industrial experience, seek out training opportunities that include an industry internship as part of the curriculum. Some biotech and pharmaceutical companies may offer volunteer opportunities,  paid internships and some still have postdoctoral positions available for qualified applicants.

Until next time...

Good Luck and Good Job Hunting!!!!!!

Interviewing Advice from a Fortune 500 CEO

In this past Sunday’s New York Time Business section there was an interview with Robert W. Selander the CEO of Mastercard who is retiring after 14 years on the job. When queried about the type of questions and information he tries to gather during job interviews, he replied:

 “Beyond the discussion of what you (the candidate) is going to do for us I want to know two or three of your strengths and weaknesses. Then I will ask you about two or three things that you acknowledged as flat sides and how you think we should work on those, how you think we should ensure those don’t become barriers to success.”

While many of you who read BioJobBlog may not be interviewing for senior management or executive-level job, it is instructive to realize that interviewers will almost always ask you to talk about your professional strengths and weaknesses. Therefore, as I have recommended in the past, it is a good idea to think about or even write down answers to the what are your strengths and weaknesses questions. But, it is important to remember that the weaknesses that you offer up must be the type that can also easily be viewed as possible strengths!

Until next time...

Good Luck and Good Interviewing

 

BioJobBlog Teams with Career Management Source to add a Career Center to Promote Real Time Life Science Jobs

BioJobBlog and Career Management Source, a producer of online applications for streamlining job searching and hiring, have teamed to create BioCareers, a life sciences job board and career center. For job candidates, BioCareers offers real time job listings, application tracking, and e-mail job alerts. Employers can post jobs, advertise jobs, search resume databases and have jobs listed on other jobs like Job Job-Job Health and Twitter jobs. 

The search engine that powers BioCareers automatically pulls life sciences jobs in real time and updates job searches when positions are filled or new ones become available. Candidates can search for jobs by location or job title. One of the nicer features of BioCareers is candidate e-mail alerts when new jobs are posted or added in real time by the search engine.

I have been looking for a dedicated life sciences jobs search engine and career management solution for the past 10 years. I stumbled upon the Career Management Source platform quite by accident but I am glad that I did. And, the best part of the deal was that I didn’t have to do any of the work—the design, setup and implementation was completed by Career Management Source representatives.

You can test the BioCareers search engine capabilities by conducting a job search using the widget found in the BioJobBlog sidebar (look left). If you are interested in viewing and checking out the BioCareers website please click here.

For those of you, who may be interested in adding a career center to your blog or website, please visit www.JobJobHealth.com or e-mail Career Management Source or call 888-865-8914.

Until next time..

Good Luck and Good Job Searching!!!!!!!!

 

Pharma and Philanthropy?

Pharmaceutical and biotechnology companies like to distinguish themselves from companies that manufacture consumer products because their products have the potential to save the lives of patients suffering from a plethora of illnesses. While a life-saving cancer treatment may inherently be more valuable than a pair of snow tires, the goal of the companies that manufacture them is to sell enough products to remain profitable. To that end, pharmaceutical and biotechnology companies have an edge over consumer products companies because drug makers can use altruism and philanthropy to market their drugs. In fact, many drug manufacturers play up their commitments to altruism and philanthropy to justify high drug prices because of the enormous costs associated with drug discovery and development. This tactic begs the question: “Just how philanthropic are drug makers?”

To answer this question The Access to Medicine Foundation created the Access to Medicine Index .which provides a benchmark on the access to medicine policies and practices of the largest global pharmaceutical companies.The index is designed to offer stakeholder and prospective investor ways to compare pharma’s social responsibility records by measuring 106 indicators that examine activities across seven criteria such as philanthropy, patents, pricing and management (see more here)

The 2010 index (only the second of its kind) ranked 26 pharmaceutical companies on their efforts to provide access to medicines, vaccines and diagnostic tests to people living in 88 countries. The companies included 20 originator (branded) companies – those who primarily market patented drugs they have developed – andsix companies whose primary business is the production and sale of generic medicines. The results are shown below:

Branded Pharmaceutical Companies

  1. GlaxoSmithKline
  2. Merck
  3. Novartis
  4. Gilead Sciences
  5. Sanofi-Aventis
  6. Roche
  7. AstraZeneca
  8. Novo Nordisk
  9. Johnson & Johnson
  10. Abbott Labs
  11. Pfizer
  12. Boehringer Ingelheim
  13. Eli Lilly
  14. Bayer
  15. Bristol-Myers Squibb
  16. Eisai
  17. Merck KGA
  18. Takeda Pharmaceuticals
  19. Astellas Pharma
  20. Daiichi Sankyo

Generic Manufacturers

  1. Ranbaxy Laboratories Limited
  2. Cipla Limited
  3. Dr. Reddy’s Laboratories
  4. Mylan, Inc
  5. Sun Pharmaceuticals
  6. Teva Pharmaceuticals Ltd.

While the lists may seem impressive, Index founder Wim Leereveld cautions: “…the industry as a whole still has a long way to go.”

Ed Silverman, who runs the Pharmalot Blog, offered his insights about the list and the foundation’s findings: “The report, of course, will be used to defuse critics, such as non-governmental organizations and activist groups, who say not enough is done to make meds accessible in poor countries. The arguments often center on compulsory licensing and free-trade agreements, as well as intellectual property disputes, pricing and donations. Pharma, you may recall, has been on the defensive ever since they fought South Africa over HIV meds, and is now ramping up operations in so-called emerging markets, many of which are low-margin operations where incomes are lower. “

I don’t fault drug makers for aggressively marketing their products to generate revenues to insure profits and growth. After all, business is business. However, I think that it is disingenuous to use altruism and philanthropy as a means to market and sell high priced drugs. Ironically, this practice tends to limit the access of poor and disenfranchised patients who might benefit the most from these medicines.

Hat tip to Ed at Pharmalot

Until next time...

Good Luck and Good Job Hunting!!!!!!!

 

Need a Quick Business Tune Up: Stanford's Summer Institute for Entrepreneurship Can Help!

The Stanford Summer Institute for Summer Entrepreneurship was started several years ago and was “designed for currently enrolled, non-business graduate students.” According to the program’s website, “The business world is in need of young visionaries with backgrounds in humanities, science, and engineering. The Stanford Graduate School of Business Summer Institute for Entrepreneurship offers current graduate students the unique opportunity to build the analytical and practical skills critical to launching a successful business.” That’s right, all you would-be entrepreneurs who want to start your won biotech company ought to check it out!

The program has been wildly successful since its inception. The 2010 class is completely full and applications for the 2011 session will be available this September. For a program overview, check out this video

Please contact Aimee Slobin for more information. Also, you can download a program brochure by clicking here.

Until next time...

Good Luck and Good Job Hunting!!!!

 

Life Sciences Job Update: Which Ones are Hot!!!

While the layoffs at pharma and biotech companies continue, the good news is that fewer jobs are being lost in 2010 as compared with 2009. Despite the massive loss of R&D and sales and marketing jobs, many life sciences companies are beginning to hire again. In general, job opportunities at emerging growth public biotech and venture-backed start-ups appear to be growing while those at big pharma and big biotech are stagnant or shrinking. Specifically companies are looking to hire:

  1. Clinical affairs managers and executives
  2. Regulatory affairs personnel and executives
  3. Commercial and operational expertise at all levels
  4. Business development executives
  5. Chief financial officers
  6. Investor relations and corporate communications professionals
  7. CEOs (venture capital investors are beginning to part with their capital again)
  8. Board of directors candidates (especially those with specific functional expertise in clinical development, regulatory affairs or commercialization)

A quick perusal of the list indicates that most of these jobs are not traditional science-related jobs and many may require additional training and expertise; especially in business. That said, now may be a good time to re-evaluate whether or not a MBA may be in your future.

Until next time....

Good Luck and Good Job Hunting!!!!!!

 

Biocareers: Some Advice for Would Be Entrepreneurs

More and more people are losing their corporate jobs because of the recession. The bleak job market coupled with diminishing opportunities for older, seasoned employees is forcing many to consider starting their own businesses to join the ranks of the self employed. However, before you take the leap, I highly recommend that you read Phyllis Korkki’s article in this Sunday’s New York Times entitled “Taking the Leap To Self Employment.

As a person who successfully made the leap, she offers amazing insights into what it really takes to be successful as an entrepreneur or small business owner. Most importantly, would be entrepreneurs must possess three important characteristics: motivation, drive and passion. If you lack any of the three, chances are that you are not cut out to be self employed or entrepreneurial enough to start your own company. Also, she aptly points out that one of the major drawbacks of self employment is loneliness. I cannot stress enough that this is the major complaint of most self employed persons that I know. 

While nobody wants to admit it, humans are social animals who need to interact with one another to fulfill the evolutionary need to be “social.” Luckily, the advent of social media has helped to overcome the daily loneliness experienced by many entrepreneurs and self employed persons. That said, before you make the leap, please read the article—it will help to determine whether or not self employment is right for you!

Until next time...

Good Luck and Good Job Hunting

 

Eight Common Mistakes Made During Job Interviews

Now that the economy is improving and the job market is loosening up a bit, the likelihood of a face-to-face job interview is increasing. The folks over at Best Online Colleges recently sent me a post about common mistakes made during job interviews and how to avoid them. While some of the proffered suggestions and tips overlap with some of my own, there are several that are new and novel and worth considering. 

Like most other things in life, practicing your interviewing skills will improve your performance and increase the probability of receiving a job offer. That said, take a look the list and see whether or not you can avoid these oft time embarrassing mistakes during your next face-to-face.

  1. Forgetting the name of your interviewer
    Often times, a company will give you the name of your interviewer when it contacts you to set up an interview. In these cases, not knowing their name as you set foot in their office is inexcusable. If first impressions are everything, then you’ve scored a zero before the process has even started. Be sure to memorize their name as soon as you get it, and if you forget, look for clues in their office – like a nameplate.
  2. Succumbing to your nerves
    Remember that you aren’t facing a firing squad – your life isn’t at stake, so don’t act like it. What’s the worst that could happen? You won’t get the job you already didn’t have? Don’t work yourself into a panic. Vomiting on your interviewer’s desk, sweating like an NBA basketball player or shaking like you’re sitting in a 727 that’s hitting turbulence are way worse than a couple of stutters. Clear your mind beforehand and keep things in perspective.
  3. Relaxing too much
    If you have too much perspective – or just nerves of steel – don’t make it apparent by propping your feet up on your interviewer’s desk, for example. Don’t make inappropriate jokes or inane comments. Unless instructed otherwise, you should act formally and business-like. Your behavior should be 100 percent professional. More likely than not, they’ll judge you based on how you act during that short period of time.
  4. Divulging too much
    In the haste to appear as open as possible, many interviewees tend to give too much information. But honesty isn’t always the best policy. Your prospective employer doesn’t need to know about the three-month-long coke binder you went on after freshman year. They don’t want to hear about how your previous boss did his best to imitate Bill Lumbergh. Only disclose what they need to hear related to your performance as an employee.
  5. Coming empty-handed and empty-minded
    Don’t give your interviewer the impression that you didn’t take any time to prepare before meeting with them. They’ve done their homework and they expect you to do yours. It’s essential that you study the company. How’s it performing? What’s its mission? How does the position for which you’re applying fit into the grand scheme of things? Be sure to bring additional copies of your resume, a list of your professional references, the job posting (if possible), and a pen and notepad.
  6. Transforming into a phony salesman
    No interviewer likes a phony – unless of course your prospective job title is “phony salesman.” But in most cases, acting overly-enthusiastic can be off-putting. They know you really want the job. You don’t have to pretend it’s the best job in the history of jobs. And don’t exaggerate your abilities. If you try too hard to say what your interviewer wants to hear, they’ll know.
  7. Cell interruption
    There’s nothing ruder than a noisy cell phone chiming in during an exchange with your interviewer. Silence your phone before entering the building. Mom’s “Good Luck <3" text message will still be there after the interview and the sentiment will remain the same.
  8. Succumbing to your ADD
    The worst is when an interviewer gives a long-winded information-filled speech and you’ve only managed to absorb the first sentence. Take a deep breath, slow your racing mind and give them your full attention. You don’t want to respond with a blank stare when they ask if you have any questions.

Hat tip to Best Online Colleges!

Until next time...

Good Luck and Good Job Hunting!!!!!

 

Why Layoffs Won't Help Big Pharma

For the past three years, I assiduously have attempted to track all of the major layoffs announced by big pharma and biotechnology companies. Quite honestly, it has been hard to stay on top of these almost weekly announcements. To date, over 200,000 life sciences employees have lost their jobs. And, I don’t think that job layoffs will abate for a year or more.

While pharma layoffs make sense in the short term—most notably to insure that stock share prices remain as inflated as possible—they are not going to solve pharma’s lack of innovation and the rising attrition rates for new molecular entities. On paper, outsourcing R&D make perfect fiscal and scientific sense. After all, there are literal thousands of US-trained scientists all over the world these days; mainly in China, India and Eastern Europe and it is much more cost effective to do research in these regions. However, in my opinion, outsourcing R&D, like layoffs, is a short term strategy that will likely backfire and not deliver the anticipated ROI. For example, many US technology companies that outsourced sizable portions of their operations in the early 2000 are now beginning to bring them back to the US as Asian labor costs continue to rise and product quality declines. This begs the question: what should big pharma companies do to regain their edge to bring new medicines to market?

Allan Haberman, of Haberman Associates, wrote a compelling post several months ago on his blog the Biopharmconsortium Blog where he offers some insights and strategies that may help big pharma out of its current lack of innovation and new product development.  Until that happens, I will continue to track pharma and biotech company layoffs as they are announced.

Until next time....

Good Luck and Good Job Hunting!!!!!!!!

 

Resumes, Curriculum Vita and Cover Letters

After almost a week advising students about the difference between resumes and curriculum vita (for scientists there is no difference), academic vs. an industrial curricula vitae and cover letters at Experimental Biology this year, I came to two conclusions. First, all scientists should take a resume writing course. Second, there is no single resource to help students and postdocs figure out a way to navigate the sometimes treacherous waters of resume writing and cover letters.

Much to my surprise and delight, Monica Kerr, who is Director of Science Alliances at the New York Academy of Sciences, offered a link to a great resource developed by Harvard’s Office of Career Development. The document entitled “CVs and Cover Letters” offers ideas and samples of academic CVs and cover letters. Further, it provides insights into formatting and verb usage when constructing CVs and resumes. While the document does not address how to construct an industrial CV, it is one of the best resources that I know of for resume writing for life scientists.

Those of you looking who may be looking for advice and guidance about constructing industrial strength CVs can check out a post that I crafted for BioJobBlog a couple of years ago. Like the Harvard document it focuses on CV formats, verb usage and other job search related items.

Hat tip to Monica (and Harvard Office of Career Development)!

Until next time…

Good Luck and Good Job Hunting!!!!!!!!!!!

 

Pharma Layoffs Continue Unabated

Pfizer today announced that it would lay off another 123 workers at its Pearl River, NY manufacturing and R&D site.

The workers in the facility's research and development division will lose their jobs by early July according to a company spokesperson. He added "There may be some additional positions eliminated over the course of 2010, but this is the last major wave that will be announced.”

This brings to 601 the total number of layoffs at the site. The cuts are part of a global restructuring Pfizer announced in November, weeks after acquiring Wyeth Pharmaceuticals. The company has yet to decide the fate of the plant's manufacturing arm. If it is shuttered, that could lead to more layoffs

In other news, lesser known KV Pharma said it would shed 289 workers or 42 percent of its workforce. KV already had reduced its staff from 1,700 in 2008 to about 680 as of Feb. 28. The company recently shut down its generics subsidiary Ethex Corp. after the company pleaded guilty to criminal charges for not disclosing problems with two of its drugs and agreed to pay $27.6 million in fines and restitution.

While the US government and financial analysts claim that the economy is show signs of improvement, the layoffs at pharma and biotech companies continue. Only time will tell if we have truly turned a corner during this economic downturn.

Hat tip to the Pharmalot blog!

Until next time...

Good Luck and Good Job Hunting!!!!!!!!

 

Patents, Genes and the Future of Biotech

The decision yesterday rendered by Federal District Court Judge Robert W. Sweet that invalidated the patents issued to Myriad Genetics for the breast cancer marker genes BRCA1 and BRCA2 is analogous to the “shot heard round the world” that kicked off the American Revolution in 1775. While it isn’t clear whether or not the decision will stand (Myriad has appealed the ruling), it does have the potential to change the way in which life sciences companies may operate in the future.

Patents are the lifeblood of the biotechnology industry. Because of this, scientists, university technology transfer offices and many would be entrepreneurs have sought to patent any and all ideas, inventions and potential products that may serve as the basis for a life sciences community. This has resulted in the issuance of a surfeit of composition of matter patents for many human and non-human DNA sequences that encode potential industrial and therapeutic proteins.

Prior to the sequencing of the human genome, many scientists and entrepreneurs had compelling and legitimate arguments to patent newly discovered DNA sequences. While these sequences existed in nature prior to their discovery, their commercial potential could not be fully realized until the genes and their products were isolated and fully characterized which generally required many years of scientific study. In contrast, however, the advent of whole genome sequencing allows scientists, to easily identify genes and their products that are likely to have future commercial potential and value. Because this renders inventions that make use of the genes or proteins themselves obvious, composition of matter patents are no longer feasible or warranted. Also, while composition of matter patents may have been lucrative in the past, it is usually secondary process patents that extend the commercial lifecycle of protein-based drugs. For example, the composition of matter patent for recombinant erythropoietin (held by Amgen) expired in 2004. However, Amgen has recombinant erythropoietin process and production patents that preclude competition in the US until 2017.

While composition of matter patents may be important for therapeutic proteins, the same isn’t true for diagnostic products. In fact, composition of matter patents in this case (like Myriad Genetics patents for BRAC1 and BRACA2) tend to stifle innovation and create monopolies for the companies that own them. The elimination of composition of matter patents for DNA sequences will give scientists the requisite freedom to operate and necessary creativity to develop new tests and uses for novel genes and their products.

To that end, the diagnostic industry would be well served if it adopted the open source business model pioneered by the software industry. This has resulted in the creation and development of new products, commercial applications and business opportunities that have exceeded the expectations of the companies that developed the original code. I see no reason why the same approach couldn’t be used in the diagnostic and personalized medicine industries as they continue to mature.  After all, the human genome is the ultimate source code and allowing free and unfettered access to its contents will undoubtedly result in many innovative, useful and previously unimagined commercial scientific and healthcare advances in the future.

Until next time…

Good Luck and Good Job Hunting!!!!!!!!!

 

The Life Sciences Industry: China Begins to Turn Up the Heat

Until recently, there was little or no mention of business activity within the emerging Chinese life sciences industry. However, as the Chinese middle class continues to grow, the need and demand for pharmaceutical and biotechnology drugs (including vaccines and other biologics continues) to grow at a frenetic pace. Further, a growing abundance of US-trained scientists has allowed the Chinese life science industry to develop much more quickly than anticipated. Also, many major pharmaceutical companies like Merck, Roche and Novartis have invested hundreds of millions of dollars in China and have already established world class Chinese R&D facilities. Finally, unlike in most Western countries, the Chinese government controls roughly 80% of the pharmaceutical and biologics manufacturing that takes place in China. Together, this suggests that China has quietly established itself as a life sciences power to be reckoned with! To that end, there were two reports that came across the transom this morning that piqued my interest. 

The first report was about a company called Lotus Pharmaceuticals, Inc.

"Lotus Pharmaceuticals, Inc., a growing developer and producer of prescription drugs and licensed national seller of pharmaceutical products in the People's Republic of China ("PRC"), reported the groundbreaking ceremony on March 9 to construct a new building complex on the grounds of its production facility in Beijing.

Officials of Beijing municipal and Chaoyang district governments, officers of the China State Food & Drug, and representatives of both state-owned and private pharmaceutical companies attended the ceremony. CEO, Zhongyi Liu, welcomed the guests. "After a year of planning, we are pleased to start the construction of the new building complex and expect to finish the construction by July, interior decoration by September and GMP certification by December of this year," he said. "This is a new page for Lotus' development and it will provide important impetus to profitable growth, which is anticipated to reach $150 million in annual sales during the first year after the facility, is fully operational."

The second reported on plans to build a venture-back, “private” contract manufacturing facility that specializes in biomanufacturing in metropolitan Beijing.

"AutekBio, Inc., SUMA Ventures and Beijing E-Town Harvest International Capital Management Corporation, a venture capital group from Beijing Municipal Government announced a joint investment of more than US$100m to develop a new contract manufacturing organization (CMO) for biopharmaceutical industry in China. This joint effort led by AutekBio represents strong interests from both private investment sector and government to establish world quality capability and capacity in biopharmaceutical manufacturing in China.

The new joint venture will build up a world class R&D and manufacturing center in southern Beijing to service international biologic developments, with combined volumes of bioreactors up to 20,000 liters in multiple production lines (trains). The firm will also benefit from financial, regulatory and other supports from the Chinese government for the biotech industry." 

It is becoming increasingly apparent that China has clearly set its sights on establishing itself as player on the global life sciences stage. After spending a week in China during the country’s preparation for the Beijing Games, I discovered that China can achieve any goal that it sets for itself in very short order.  

Until next time...  

Good Luck and Good Job Hunting (try China)!!!!!! 

 

Another Biotech Company Bites the Dust

Abbott Laboratories yesterday announced that it will buy Facet Biotech Corp. for about $450 million in cash. Facet, along with its development partner Biogen Idec, had planned on moving a potential monoclonal antibody (MAb) treatment for multiple sclerosis called daclizumab into late stage clinical development in the second quarter of this year. The company is also developing several different cancer treatments with other pharmaceutical partners.

Abbott’s purchase of Facet signals Abbott Laboratories’ ongoing commitment to biotechnology or protein-based drugs. The company launched Humira (a fully human MAb treatment for rheumatoid arthritis and other inflammatory diseases) several years ago and it has managed to glean market share from older competitor’s products including Remicade (Johnson & Johnson) and Enbrel (Amgen/Pfizer) to become a blockbuster drug. MAbs are viewed by many as the “drugs of the future.” At present, there are over 350 MAb-based products in various stages of discovery and clinical development.

Earlier in the year, Biogen Idec offered to purchase Facet for $17.50 per share. Company executives and shareholders rejected the offer citing that they thought it was too low. Abbott offered $27 per share which represented a 67 percent premium to Facet’s closing stock price of $16.21 on Tuesday.  Both companies’ boards of directors have already approved the deal which is expected to close some time in the second quarter. It is not clear how the purchase will affect Facet employees but expect to see layoffs and a mass exodus by company executives.

Look for more cash purchases of biotech firms by pharmaceutical companies as debt continues to accrue and venture money remains scarce and difficult to come by.

Until next time...

Good Luck and Good Job Hunting!!!

 

Input on Social Media Regulatory Guidelines Continues to Trickle in from Life Sciences Companies and Trade Groups

Mark Senak, author of the incisive EyeonFDA blog and de facto watchdog of all things social media in the life sciences, has assiduously been tracking company and trade organization input to the docket for the Part 15 meeting on medical product promotion and the internet and social media. To date, according to Mark, the following companies and trade groups have officially submitted their comments and viewpoints to the docket                                                                                              

  1. Covidien
  2. Johnson & Johnson
  3. Bayer Healthcare
  4. Sanofi Aventis
  5. AstraZeneca
  6. Eli Lilly
  7. Medtronic
  8. Pfizer
  9. Abbott
  10. Novartis
  11. Genentech
  12. Sepracor
  13. Merck
  14. Medtronic
  15. Biotechnology Industry Organization (BIO)
  16. PhRMA
  17. National Organization for Rare Disorders (NORD)

As you may recall, industry input was lacking and surprisingly absent from the public hearings held by FDA on the topic earlier this year. While news analysts and bloggers were incredulous that companies didn’t actively participate in the earlier public hearings, this behavior is typical of life sciences companies that like to do things quietly and, when possible, behind closed doors. Ironically, this lack of transparency and inclination to secrecy is the antithesis of social media. Is it any wonder then, that life sciences companies are suspicious and wary of the impact that social media may have on their ability to conduct business?

Until next time...

Good Luck and Good Job Hunting!!!!!!!!

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BioJobBlog Makes a Top 50 Biotech Blog List

Emily Johnston of Medicareer sent me a message last night to inform me that BioJobBlog made its top 50 biotech blog list. While I don’t know much about Medicareer (nor does BioJobBlog have a business or financial relationship with the organization) this is a first for the blog and it is quite an honor to be included on the list. I guess spending hundreds of hours over the past three years writing blog posts is actually beginning to pay off!

A quick perusal of the list reveals some very interesting and useful biotechnology blogs that are worth reading. And, surprisingly, there are a couple of blogs on the list that I previously didn’t know about.

Hat tip to Medicareer!

Until next time...

Good Luck and Good Blogging

 

Economic Recovery: US Contract Biomanufacturing Companies Are Experiencing an Upswing

For the past decade or more, small to mid-sized biotechnology companies had been outsourcing production of their preclinical and clinical protein-based products to Asian contract manufacturing organizations (CMOs). This was because manufacturing and labor costs were lower and product quality was consistent with Western standards and requirements. However, the recent economic down turn coupled with rising prices at Asian CMOs (mainly driven by increasing labor and project management costs) has forced many small to mid-sized companies to rely again on American CMOs to manufacture their products. Unlike cash-rich, larger companies, US small to midsize companies generally lack the financial resources and personnel to effectively manage operations in Asia. Many industry analysts contend that the lower initial costs of Asia-based companies are usually offset by the money and resources need to oversee a project.

While business returning from Asia improved the financial outlook for some American CMOs, 2009 was a bad year for most firms that service small to mid-sized pharma and biotech companies. However, industry analysts expect 2010 to be better than 2009. More importantly, the return of biomanufacturing to the US may signal the beginning of a new trend in the biomanufacturing outsourcing industry.

Until next time....

Good Luck and Good Job Hunting!!!!!!!!!!

 

Spurring Innovation

American competitiveness in engineering, technology and science. Unfortunately, while American competitiveness and innovation in these areas continues to wane, little has been done (except talking) about it! Yesterday, Intel and 24 venture capital funds announced that they plan to invest $3.5 billion in American startups and early stage ventures over the next two years. Further, in addition, several of America’s leading technology companies including Google, Cisco Systems, Intel Microsoft and 13 others pledged to add as many as 10,500 jobs into 2010—mainly by hiring Americans graduating from colleges with degrees in computer science and engineering.

The initiative, named the Invest in America Alliance was formed in response to “steadily declining long-term investments in education, technology and human capital” that has been taking place in the US for past 20 years or more. Put simply, the American education system is not training enough qualified individuals to allow the US to compete with other emerging technology and engineering powerhouses that include China, India Finland, Korea and the Netherlands. 

According to Robert Compton, a venture capitalist, entrepreneur and education enthusiast “Fewer than 10 percent of college graduates in the US have engineering degrees, compared with more than one-third in India and China and more foreign-born graduates of US universities are returning to their home countries.” For those of you with degrees in math and science (and you base your calculations on population size), the magnitude of the problem (for Americans anyway) is glaringly obvious. Compton went on to say what many others have been thinking for a while, “Early indicators are that we are not the center of innovation anymore. It is shifting to the East.” And he may be right! Based on surveys conducted by the World Intellectual Property Organization in the last year, patent filings increased 30 percent in China while declining 11 percent in the US.

While the Invest in America Alliance appears to be a great public relations opportunity for the companies and venture firms that are participating in it, its critics doubt whether investing more money in technology startups is going to fix the ongoing problem. Education analysts contend that a better and cheaper solution may be changing US immigration laws so that foreign students who train in the US are allowed to remain in the country after they complete their training. Other naysayers contend that most of the venture money committed by the alliance would have likely gone to American startups anyway (US based venture firms already invest 70 percent of their money in American start ups) and that 10,500 new jobs isn’t enough to make a dent in the US unemployment rolls.

Like the technology industry, a decade of wrong-head immigration policies coupled with a waning American interest in science has begun to jeopardize the US dominance in the life sciences. Further these trends are largely responsible for the massive layoffs and unrelenting outsourcing of pharmaceutical R&D jobs to foreign countries.

Toothless or not, the Invest in America Alliance shows that engineering and technology industry leaders are willing to cooperate with one another and get behind an initiative that raises public awareness about America’s waning competitiveness in these fields. Perhaps,   pharmaceutical, biotechnology and medical devices and diagnostic companies ought to take a page out of the Alliance’s play book to similarly insure the future innovation and competitiveness of the American life sciences industry.

Until next time...

Good Luck and Good Job Hunting!!!!!!!!!

 

Carl Icahn Takes Aim:Setting His Sights on Genzyme

Carl Ichan, the billionaire, activist investor notified Genzyme that he will seek shareholder approval to seat four handpicked directors including himself to be appointed to the company’s board of directors in an attempt to remove embattled Chairman and CEO Henri Termeer who has led the company for the past 25 years.

The move was widely anticipated by industry analysts because Icahn own one percent of outstanding shares of Genzyme’s stock.  Icahn and other large shareholders believe the company would be better off under new leadership. Termeer has publicly stated that he has no intention of resigning.

Until recently, Genzyme’s standing and reputation in the biopharmaceutical and orphan drug industry was second-to-none. However, the company’s inability to quickly correct ongoing manufacturing problems at its biomanufacturing facilities for the past year has been extremely embarrassing and costly. Sloppy manufacturing and quality control problems this past year led to major shortages of two main products, Cerezyme and Fabrazyme. Consequently, in 2009 sales revenues dropped and company earnings were almost flat. Further, Genzyme shares lost 26% of their value in 2009, sinking to a five-year low.

Icahn is no stranger to hostile corporate takeovers and company sales. In spring of 2008, he unsuccessfully tried to gain control of the Biogen/Idec board to force the sale of the company (Ichan owns 5.6% of Biogen/Idec’s outstanding shares). Later that year, Icahn engineered the sale of ImClone to Eli Lilly for $7.0 billion; after getting into a very public and often acrimonious fight with Bristol-Myers Squibb CEO Jim Cornelius who tendered a “low-ball offer” (according to Icahn) to purchase ImClone.

According to my calculations, Icahn is batting .500 for his recent corporate takeover attempts. Do you think he will be able to go 2-for-3? I bet Henri Termeer is hoping that he can’t!

Until next time...

Good Luck and Good Job Hunting!!!!!!!!!!

 

Considering a Career in Regulatory Affairs? A Fellowship at FDA Won't Hurt Your Chances

As many of you already know, I talk to a lot of graduate students and postdoctoral fellows who are disillusioned with the prospect of remaining in the laboratory for the rest of their lives. Frequently, students mention regulatory affairs as an alternate career option and ask me what type of training and skills are required to transit into a regulatory career. Unfortunately, regulatory affairs is an industry specific career and regulatory affairs training programs with the possible exceptions of the courses offered by the Regulatory Affairs Professionals Society (RAPS) and the Drug Information Association (DIA) (which can be costly) are not readily accessible to graduate students and postdoctoral fellows. Consequently, I recommend that PhD-trained scientists who are interested in regulatory affairs check out employment opportunities at the US Food and Drug Administration (FDA). This is because there is no better place than FDA to learn the “ins and outs” of regulatory affairs!

Until recently, jobs, fellowships and training programs at the agency were scarce. However, while reading an industry trade magazine I came across an ad (posted below) announcing fellowship opportunities for PhD level life scientists, healthcare professionals, pharmacists and even engineers(although they only need a bachelors degree to be eligible.

This is an opportunity for those interested in a regulatory affairs career to give it a shot! For more info visiting the agency’s website

Until next time...

Good Luck and Good Job Hunting!!!!!!!!

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An Analysis of Social Networking Sites for Life Scientists

Mary Canady author of the Comprendia Blog recently analyzed the popularity (or lack thereof) of a number of social networking sites that were created for life scientists. It would seem that online social networking sites would be ideal for scientists because we are not known for our networking or social communication skills in real life. However, only a few of the more than 15 life sciences social networking sites started in the past two years are doing well based on the traffic and usage statistics cited by Mary in her post. 

While Mary’s analysis included most of the well known life science social networking sites, she failed to include BioCrowd, the networking site started by Vincent Racaniello and me. While BioCrowd does cater to life scientists, we intentionally expanded our network to include other bioprofessionals including medical writers, marketers, consultants, venture capitalists and even CEOs! After all, it takes a village to take an idea from concept to commercialization.

Hat tip to Mary for the insightful post!

Until next time...

Good Luck and Good Job Hunting!!!!!!!

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The Job Search: How to Stand Out in the Crowd

It goes without saying that the competition for jobs in the life sciences industry is extremely fierce. This means that job candidates must use whatever means possible to differentiate themselves from the hundreds, perhaps thousands, of others applying for the same job!

While I have written numerous posts on how job candidates can stand out from their peers, I discovered an insightful article that summarizes my advice in a single post. Like I said, there are no revelations here; just a convenient way to jog your memory as the job search slogs on!

Click here to read the post.

Until next time...

Good Luck and Good Job Hunting!!!!!!! 

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Merger Aftermath: Pfizer Refocuses

While I never was involved in a corporate acquisition or merger, I have many friends who have lived through them and based on their experiences it is a never a “pretty sight.” Merger aftermaths usually feature massive layoffs, executive management disputes and turf wars and corporate culture clashes tha occur when two workforces are forced to merge as one. However, sometimes mergers may be a good thing for struggling companies. To that end, Pfizer may actually benefit from it $68 billion acquisition of Wyeth late last year.

The acquisition will cost at least 20,000 employees their jobs—not a good thing in a national economy where unemployment is well over 10 percent (despite claims to the contrary). However, this merger is strikingly different than Pfizer’s questionable past mergers and acquisitions which were primarily engineered to procure one or two drugs that had blockbuster potential e.g. Lipitor and Celebrex. This time around, Pfizer’s management team is actually re-evaluating its entire drug development portfolio and attempting to expand the company’s pipeline to include vaccines, therapeutic proteins and other biologics. As I previously noted, most major pharmaceutical companies believe that biologics will be the major driver of pharmaceutical markets in the not so distant future.

According to a post on PharmaLive, Pfizer announced that it will discontinue research and development on roughly 100 experimental new drug candidates. Pfizer officials revealed that the company will continue with 500 research projects in six areas of: 1) Alzheimer’s disease, 2) diabetes, 3) pain, 4) cancer and 5) mental illness (including schizophrenia).

Of the 500 projects, 30 drugs are being tested for cancer indications, 10 for Alzheimer’s disease, eight for pain and 11 for inflammation. Further,133 are in various stages of human clinical testing, including several that are awaiting regulatory approval in the US and elsewhere. 

On the biologics front, Pfizer has six vaccines and 27 biopharmaceutical drugs in development. Prior to the Wyeth acquisition, the company only had one vaccine and 16 new biologics that it was testing. Like most other pharmaceutical companies, Pfizer wants to be a major player in the biopharmaceutical and biologics markets by 2015.

Only time will tell!

Until next time,

Good Luck and Good Job Hunting!!!!!!!

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The Job Slog: Several Challenging Interview Questions that Mid Career Bioprofessionals May Have to Answer

There is no question that job opportunities for recent life sciences undergraduates, graduate students and postdoctoral fellows are becoming increasingly difficult to find. While this is troubling, older, mid-career bioprofessionals who may be looking for new jobs and challenges are having a rougher go of it. This is because older employees generally cost more to hire and many employers mistakenly believe that seasoned employees make lack the drive and technological skills as compared with younger, less experienced jobseekers.

Whether or not these assumptions are true, the interview questions that older job candidates may be asked are likely to be different than those offered up to younger prospective employees. To that end, there was an informative “how to” blog post written by Shelbi Walker of Back to Work, Inc that offers older professionals some responses that older job candidate can use to answer challenging questions that they may encounter during a face-to-face job interview.

I listed some sample questions and acceptable possible responses to them below:

1.  You appear to be overqualified for this position. Won't you get bored?

Suggested Responses:

“You are an excellent company. You deserve excellence in employees."

“Experience is a great premium today.”

“There is a greater return on your money if I hit the ground running. Less training time.” 

“I always like for additional work to do to prevent from getting bored.”           

2.  This company is on the fast track. Do you think that you can keep up?

Suggested Responses:

“I have stayed on top of the latest development in our industry and am computer literate." (Use this opportunity to showcase any training classes or courses you have taken.)

Also, consider hitting this question head-on by stating politely that you have not noticed any slowdown in attitude or energy. 

3.  This isn’t exactly the type of job you have done in the past. Can you tell us how you will transfer your skills?

Suggested Responses:

"I have viewed your website and read everything about your company.” (Then, draw some analogy to a previous area of expertise, and relate it to the new company's product or service).

4.  I noticed that you have been out of work for over six months. Can you explain this break in employment?

Suggested Responses:

"I explored some other options but they weren’t for me.  I feel that I have many more years of productivity left to work in this industry."

“I am looking for something different. I am fortunate to be in a position to take time to make sure this job is right for both of us. "

"I used this time to brush up (or learn) a new skill, and now I am ready to contribute my knowledge and expertise to an exciting company like yours."

5Why do you think you are qualified for this job? I don't see where you have experience that would match our business needs

Suggested Responses:

"My excitement at learning new things never diminishes. With my work experience, I know I will be a quick learner." Take this opportunity to point out any skills you have added to your repertoire. Identify a skill you have, and align it to something you would need to do on the new job.

6.  Your resume indicates you have worked at a lot of different places. Can you comment on that?

Suggested Responses:

“Each of those positions broadened my knowledge and skill base."

“It does appear that way, but, in the last 10 years, the economy has been such that mergers have forced a number of us to realize our potential in various environments." (Always turn a perceived negative into a real positive!)

7.   You were with your last company for 19 years. Can you change the way you did things?

Suggested Responses:

"I am looking for change!"

"My last company underwent many changes during that time, and I enjoyed trying new things and ideas." (Give examples whenever possible.)

8.  I see you have been a consultant. Does that just mean you were out of work?

Suggested Responses:

" My old company brought me back on contract to complete several projects, which I did — and now I want to see if there is something more exciting out there. "

“ I understand lots of people are calling themselves consultants while they look for a new position. " (Laugh — sometimes, it's OK to insert a little bit of levity.)

9.  What salary are you looking for (the implication that is may be too high because you have been in the workforce so long)

Suggested Responses:

Never respond with a specific dollar amount. Affirm that you have vast skills and experience. Indicate that you are either willing to start over to show them what you bring to the table or deserving of top dollar.

Alternatively, ask the interviewer what dollar amount is allocated for the position in this year's budget. And, finally ask the interviewer whether or not they are offering you the job since you are discussing salary requirements!

While I can’t guarantee that you will be asked any or all of these questions at your next job interview, they are food for thought!

Until next time...

Good Luck and Good Job Hunting!!!!!!!

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Issues Surrounding the Use of Social Media in the Life Sciences Industry are Still Alive and Well

Despite rumors of impending demise and premature death, the issues surrounding the use of social media in the life sciences industry are still alive and relevant. To that end, the Business Development Institute is sponsoring a “Healthcare Social Communications Leadership Forum Breakfasts on February 4, 2010 at New York University in Manhattan. The conference is limited to 75 attendees. While there are seats still available they are rapidly disappearing. 

Some of the topics to be discussed include:

  • How to connect with consumers who are already using the internet for healthcare information?
  • What are the case studies of leading brands that use internet based social strategies to achieve communications objectives?
  • What are examples of social communities that demonstrate how leading healthcare brands interact, educate and provide value to consumers online?
  • How to deal with regulatory and legal issues when planning and implementing social and internet based strategies
  • Why real-time social media tools, such as Twitter, are gaining momentum and what's the business case to use them
  • How to sell projects and prove ROI to senior management
  • What are the tools, technologies, and best practices for monitoring and measuring internet based programs?

Scheduled presenters and panelists are:

  1. Michael Fleming, Senior Director, Social Media, GlaxoSmithKline
  2. Robert Halper, Director of Video Communication, Johnson & Johnson
  3. Lance Hill, CEO, Within3
  4. Ray Kerins, Vice President / Worldwide Communications, Pfizer Inc.
  5. Marc Monseau, Director, Corporate Communications & Social Media, Johnson & Johnson
  6. Rodney Spady, Head of Global Interactive Marketing and Web Officer, OTC Global Marketing, Novartis Consumer Health, Inc.

For more information, including registration, please click here to visit the event website. Use promo code BIOC before February 3rd for a discounted rate of $175.

See you at the meeting!

Until next time...

Good Luck and Good Job Social Networking!!!!!!

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Study Finds that Funding for Life Sciences Research Continues to Wane

Ed Silverman, over at the newly reinvigorated Pharmalot Blog, today reported that a recent study publicized in the Journal of the American Medical Association showed that, after a decade of doubling, the rate of increase in biomedical research funding slowed from 2003 to 2007, and after adjusted for inflation, the absolute level of funding from the National Institutes of Health and industry appears to have decreased by 2 percent. The NIH remains the largest federal contributor to biomedicalresearch, accounting for 84% of total federal funding in 2007 

Further, the report indicated that research funding provided by pharmaceutical and biotechnology companies and medical devices and diagnostics manufacturers rose from $40 billion in 2003 to $58.6 billion in 2007; an increase (adjusted for inflation) of roughly 25 percent. Most of the funding came from large pharmaceutical companies. Interestingly, however, the sector of the life sciences industry that exhibited the greatest increase in growth over the same period was diagnostic and device makers (59 percent), followed by biotechnology (41 per cent) and lastly, pharmaceutical companies (25 per cent).

While the results of the study are not surprising, it is clear that the life science sector is beginning to focus more on device and diagnostics than on small molecules and even biotechnology products. Further, reductions in federal funding are forcing researchers to increasingly rely on grants and contracts from private sector companies. This suggests that an ever expanding percentage of the research conducted at many academic institutions will be financed and underwritten by for profit companies. Although more product-focused academic research is not necessarily a bad idea, it does call into question the direction and possible breadth of academic research and the availability and sharing of important scientific information, data sets and discoveries. 

Until next time...

Good Luck and Good Grant Writing!!!!!!!!!

 

Pfizer Survey: Physicians Favor Using an Electronic Health Records System to Report Adverse Events

I realize that I have been blogging about adverse events for the past couple of day but, let’s face it; the pharmaceutical industry lives or dies by the number of adverse events (AEs) that are reported for approved and marketed drugs. In any event, I came upon an interesting post in a Pharmaceutical Processing e-blast about the results of a survey  (conducted by Pfizer) which revealed that physicians are more likely to report side effects and adverse events through an electronic health records (EHR) system as compared with traditional paper methods. Nearly 60 percent of the 300 physicians who responded to the survey also agreed that AE reporting through an EHR would improve patient care.

While the results of the survey are not surprising (to me anyway), they suggest that the use of electronic methods for adverse events reporting may be a boon to drug manufacturers that are required (by FDA and other regulatory agencies) to collect information regarding the safety and tolerability of approved and marketed drugs.

In a previous post, I opined that social media would be an ideal platform for AE reporting. The results of the Pfizer survey tend to support this supposition. While EHR aren’t exactly social media, they are electronic and, it appears to me (based on Pfizer survey results), that healthcare providers and consumers may be more likely to report potential AEs using electronic as compared with conventional methods. Put simply, electronic reporting is much simpler, quicker and more facile than the current pen and paper model for AE reporting. And, in today’s rapidly paced and hectic world, time savings can translate into cost savings and improved efficiencies.

Paradoxically, the Pfizer survey results tend to contradict the notion that social media would be a bane to AE reporting for most drug makers. As I mentioned yesterday, many drug makers who have almost universally shunned social media, contend that the use of social media would overburden their AE reporting systems and possibly put them at enormous legal and regulatory risk. However, as I pointed out many times in the past, AEs are an expected reality in the pharmaceutical, biotechnology and medical devices industries. And, while drug makers are deathly afraid of AEs and reluctant to learn of them, the more information this is available about potential safety and tolerability issues, the better off most drug manufacturers may be. For example, if Merck was alerted earlier about the cardiovascular problems that Vioxx patients were experiencing, then possibly fewer patients may have been affected and harmed and perhaps, an improved version of Vioxx, an effective pain medication, might still be availability to patients who benefit from it.

To that end, providing physicians, healthcare workers and consumers with an accessible e-based AE reporting system built around social media would allow drug makers to quickly determine whether or not one of their drugs exhibits tolerability or safety issues that might warrant further investigation.  And, I believe that putting the appropriate social media AE reporting systems in place would allow drug and device manufacturers to monitor the performance of their products in real time and more accurately monitor, collect and analyze safety and tolerability data for certain drugs. This, in turn, would likely lead to the development of improved safer and more effective medications and devices, lower drug development and manufacturing costs and ultimately reduce drug makers’ exposure to legal and regulatory actions.

Until next time...

Good Luck and Good Job Hunting!!!!!!!!!!

 

Signs of an Economic Recovery? Spending on Direct-to-Consumer Advertising is on the Rise Again

A post on the Pharmalot blog today reports that spending on direct-to-consumer pharmaceutical advertising came bounding back in the third quarter —rising 15 percent to $1.16 billion, according to DTC Perspectives (which cited data from TNS Media Intelligence).

The increased spending marks the first quarterly gain in nearly two years after slumping 6.4 percent earlier this year from January to June. According to the Pharmalot post, “Internet spending increased the most—more than tripling between January and September to $221 million (display ads only). And, more ads were placed in newspapers, which showed a 25 percent gain to $104 million during the same period.

During the first nine months of 2009 the leading advertisers by brand (each of which spent more than $125 million each) were:

  1. Lipitor (Pfizer)
  2. Abilify (Bristol-Myers Squibb/Otsuka America)
  3. Cymbalta (Eli Lilly) and
  4. Advair (GlaxoSmithKline)

Could this be a sign that the pharmaceutical industry thinks that the economy is improving? Alternatively, maybe pharma marketers think that people might become increasingly stressed by the economy and drugs like Abilify and Cymbalta (a variety of psychiatric indications) and Lipitor (high blood pressure, cardiovascular disease ands stroke) may be in greater demand. And finally, from a completely cynical perspective, maybe drug makers want to sell as many drugs as possible before healthcare reform and possible price controls kick in?

Hat tip to Ed!!!!

Until next time...

Good Luck and Good Job Hunting!!!!!!!!!

 

Jobseekers: Treat Your Search like a Full Time Job

Losing a job or getting laid off is without a doubt one of the more emotionally devastating events that most people face. Unfortunately, in these troubling financial times, many more people are likely to face this likelihood than any other time in recent history.

However, if you lose or have lost a job, it is important to keep your situation in perspective and realize that it isn’t the end of the world and that there are things that you can do to find a new job! Having said that, like most other things in life you will have to work hard to achieve that goal! This will require organization, commitment and dedication to the job search. And, the best way to conduct a successful job search is to approach it and treat it like a full time job! To that end, attempt to divide each day into manageable list of tasks and allocate sufficient time to accomplish them—just like you would at a full time job. Also, since time is usually no longer an issue, you can spend some of your time researching new opportunities, networking with others or finding new contacts who might be able to help you get your foot in the door at a prospective employer’s company or organization.

Sitting in front of a computer all day, applying for online jobs on company websites and job boards isn’t going to cut it—mostly because you won’t hear back from most of the places where you submitted online job application. In fact, I think that the online approach to job hunting almost guarantees that you will become dejected, depressed and hopeless. 

In my opinion, the best approach to a job search (after losing a job) is to recognize that anything less than full time commitment to finding a new one likely won’t be successful. Based on my own and other’s experience, a successful job search consists of a mixture of focused and disciplined online and IRL activities. Developing and implementing an ordered and strategic job search provides jobseekers with organization and a “structure” that will likely help to ward off feelings of confusion, dejection and hopelessness experienced by most people who have lost jobs. For more ideas and suggestions on how to transform your job search into a full time job please check out this excellent article by Phyllis Korkki.

Until next time....

Good Luck and Good Job Hunting!!!!!!!!

 

And Now for Something Completely Different: North Carolina-based Talecris to Add 259 Biomanufacturing Jobs

Talecris Biotherapeutics announced that it will add 259 jobs as part of a $269 million expansion of its manufacturing facility in Clayton, NC. The RTP-based biotech company already employs more than 3,000 people world wide (2000 in the Raleigh-Durham area and 1,500 in Clayton) and plans to use the 259 new hires to staff its newly expanded manufacturing facility at the Clayton site. The jobs being added will have an average annual salary of $51,066, excluding benefit substantially higher than the salaries of other non-biotech employees in the area.

The company manufactures and sells Prolastin an FDA-approved protein therapy, delivered via a plasma infusion, for patients who have alpha1-antitrypsin (AAT) deficiency, which can lead to emphysema. Talecris, was formed in 2005 when private equity firms Cerberus Capital Management and Ampersand Ventures purchased Bayer AG’s plasma division for $300 million. The company was sold last year to Australia’s CSL, Ltd last year for $3.1 billion and raised $950 million in an initial public offering of stock on this past October.

 

Career Development for Life Scientists: An Ongoing and Disturbing Trend

For the past 10 years or so, I have been providing career counseling and development seminars and workshops for life scientists. In the early years, students, postdocs and a smattering of faculty members would attend to learn about industry trends, the job market and more recently, alternate careers for PhDs and postdoctoral fellows. However, over the last few years, a disturbing trend has emerged—the lack of faculty participation at these events

Yesterday, I was invited to participate as a panel member to moderate a career development event sponsored by the graduate student and postdoctoral associations at the University Of Rochester School Of Medicine. The event was well attended (over 85 participants) and the discussion lasted for more than 2 hours. Joining me on the panel was a PhD-trained scientist/manager from Bristol Myers Squibb and a healthcare company executive who received his PhD degree from the university about 16 years ago.

Many of the questions asked by the participants were spot on and revealed that graduate students and postdoctoral fellows are extremely anxious about their futures. The panel did its best to describe what it takes to get a job in the life sciences, the process and steps required to successfully win jobs and some ideas for alternate career options for PhD-trained scientists. Unfortunately, not a single University of Rochester medical school faculty member attended the event. In fact, I met the PI of one of the postdocs who sponsored my visit and he said with all sincerity (I think) “Thanks for coming...the students are really looking forward to your talk.” Obviously, I don’t think that it ever crossed his mind that he, like his students and postdocs, might learn and benefit from a discussion about career options and hear (probably for the first time) how anxious and fearful his and other students are about future job prospects.

The fact that faculty members are routinely eschewing career development seminars and forums is troubling and extremely disturbing for a variety of reasons. First, as I have said many times before, I believe that PIs have moral and ethical obligations to help their students determine what careers that they are best suited for. I don’t think that it is too much to ask or very labor-intensive for PIs to learn about the job market outside of academia.

Despite an ongoing lack of tenured track faculty positions and the extremely fierce competition to win them, academicians continue to exclusively train and prepare students for academic careers. This makes absolutely no sense from a “supply and demand” perspective. Second, the lack of faculty support and participation sends a clear message to graduate students and postdocs that their anxieties, fears and concerns about job prospects simply isn’t that important to their PIs.  The mantra of most academicians —“just continue to do good science and everything will be okay”— is outdated, anachronistic and self serving (for PIs) at best.  

Finally, and perhaps most importantly, the failure of  tenured faculty members to actively engage and participate in discussions about career options reveals the unbridled contempt that most academicians have for scientists who work outside of academia. Most academics choose to not concern themselves with non-academic and mundane issues like jobs and careers. And why should they? Once they win tenure, their lives are set because they are guaranteed jobs and benefits for life!

We are living in very challenging and troubling times. In the past three years, over 180,000 pharmaceutical workers have  lost their jobs and national unemployment will likely hit 15%. Academic and government jobs are hard to come by and the competition for these jobs is ferocious and extremely competitive. And, sadly, current academic training programs are woefully inadequate to prepare graduate students and postdocs for alternate career opportunities in the life sciences. 

As I have stated numerous times before, life science graduate training programs are in dire need of systemic change and must be overhauled to remain relevant. Unfortunately, systemic changes are unlikely because tenured faculty members can’t be forced or induced to change their attitudes or beliefs. While a minority of life sciences faculty members realizes that the system is broken, the majority doesn’t.  To that end, if graduate students and postdoctoral fellows want change to occur, than they must band together and collectively send a message to their PIs and mentors that “We are mad as hell and we aren’t going to take it anymore!” Anything short of a widespread, massive protest will be ineffectual!

To learn how to more effectively manage employees, please check out the 360 feedback solution.

Until next time...

Good Luck and Good Job Hunting!!!!!!!!

 

Pfizer/Wyeth Announces Plans to Consolidate and Reduce R&D Activities at Collegeville, PA and Pearl River, NY Sites

Employees of Pfizer/Wyeth were notified earlier today of impending changes and consolidation that will be taking place at the newly combined company. According to internal sources, Cambridge, MA, Groton, CT and Pearl River, NY will be the main centers of the combined company’s East Coast operations and San Francisco and La Jolla/San Diego CA will represent West Coast operations. In Europe, the research facility in Sandwich, England will be the main R&D center with a network of smaller sites, in locations such as Montreal, Ottawa, Cambridge UK, Aberdeen UK, and Dusseldorf, Germany providing expertise in vaccine production and biomanufacturing. The company’s China R&D Center in Shanghai will remain the focal point of operations in Asia,

There will be substantial reductions in headcount and the company’s R&D footprint. These include:

  • The former Pfizer headquarters in New London, CT, which will be consolidated into the nearby Groton, CT site. Functions currently located at New London will be relocated to Groton
  • Elimination of all R&D activities at Princeton, NJ; Sanford and the Research Triangle Park, NC; Chazy, NY; Rouses Point and Plattsburgh, NY; Gosport, Slough and Taplow, UK
  • R&D activity will be substantially reduced at the Collegeville, PA and Pearl River, NY sites. Pearl River will remain a center for vaccine and biopharmaceutical development

I suspect that many of the employees who will lose their jobs as a result of the consolidation have already been or will be notified shortly of their fates. It is unfortunate that pharmaceutical companies continue to lay off thousands of employees when the US unemployment rate continues to rise and will likely hit 12 to 13 percent before it is all said and done. As expected, the combined company is reducing its US R&D operations and will likely outsource or purchase these activities from external sources. It is not a good time to be an American R&D scientist.

Until next time...

Good Luck and Good Job Hunting!!!!!!!!!

 

Conference Round Up: e-Patient Connections 2009

e-Patients Connections 2009 (#epatcon) was held this past Monday and Tuesday at the Park Hyatt hotel in Philadelphia, PA. BioCrowd was one of several co-sponsors of the event. The theme of the conference, organized by Kevin Kruse a veteran medical communication and training expert, who now runs Kru Research, was to “reach, engage and educate empowered digital health consumers.” And, boy, did it deliver! While this was Kru Research’s first official conference, it was well organized, extremely interactive and the quality of the speakers was second to none! Topics that were featured included social media and the life sciences industry, technological advances in e-based healthcare delivery, the relationship between the news media and healthcare information and the continuing evolution of online and e-based healthcare communities.

Conference attendees included representatives from the life sciences industry, medical communications experts, advertising and marketing professionals and a multitude of social media enthusiasts and consultants who kept the Twitter screen humming throughout the meeting (a big shout out to the “troublemaking table”). And, surprisingly, there was a representative from the Division of Drug Marketing and Advertising and Communications (DDMAC) at the US Food and Drug Administration, who I believe, was one of the most sought after individuals at the meeting. CNN reporter Elizabeth Cohen who writes the Empowered Patient and racecar driver Charles Kimball, a type I diabetic and company spokesperson for Novo Nordisk also gave talks.

My favorite talks were those presented by online patient community organizers including Tricia Geoghegan of Ortho-McNeil-Janssen Pharmaceuticals who created the Facebook ADHD Allies community, Lisa Tate of WomenHeart and Robert Schumm of Bayer Consumer Care who created Facebook Strong@ Heart and Rachel Lewinson of the Juvenile Diabetes Research Organization and Susan Harrow Rago of Novo Nordisk who created Juvenation.org a website dedicated to those with Type I diabetes. These communities are outstanding examples of how partnerships between pharmaceutical companies and advocacy groups can help to better educate the public and heighten awareness about potentially life-altering diseases. Another example of a great online community and healthcare portal is Insomnia 123.com. This website was conceived and constructed by Christine Macadams and her partners’ one of whom is a practicing physician. Unlike the other online communities, which are sponsored and mainly supported by consumer healthcare division of large pharmaceutical companies, Insomnia 123.com was exclusively created by a group of concerned individuals who wanted to better educate and improve the lives of people with insomnia—a largely unreported and self-medicated condition.

On the technical side, the talks presented by Lee Segal of Klick, Kevin Durr of Avantera , Ian Kelly of Red Nucleus and Scott Ballenger of ListenLogic were illuminating and extremely informative. Some of the innovations taking place in digital media are exciting and almost overwhelming at times (even for a social media enthusiast like me). I think the company to watch is ListenLogic which uses semantic search engines to collect real time data and “chatter” on the web. This technology may provide a cost-effective solution to assuage the concerns of many life sciences companies that claim that collecting and analyzing overwhelming amounts of data is one of the main reasons why they are reluctant to entry the social media space.

Marc Monseau of Johnson and Johnson gave an illuminating talk on his experiences as a corporate blogger and Twitter user and described some of the challenges that had to be overcome before his company was able to break the “social media barrier.” Janice McCallum, an economist by training and a healthcare communications and media expert gave an informative talk about the growing role and impact of patient-generated healthcare content on patient awareness and education.

Finally, the novel and innovative Pecha Kucha sessions were outstanding and extremely well done! While all were expertly crafted, Dr. Val’s and Jonathan Richman’s Pecha Kucha were memorable. Dr. Val’s, which was extremely powerful and moving, was performed entirely in verse and Jonathan’s was—well, one of Jonathan’s always entertaining and informative presentations.

In summary, the “e-Patient Connections 2009” was a resounding success and in my opinion reached its goal to “reach engage and educate empowered digital health consumers.” That said, I can’t wait for “e-Patient Connections 2010” meeting!!!

Hat tip to @ellenhoenig and @eileenobrien for inviting me to my first tweetup (great fun) and finally meeting @janice McCallum, @christianeTrue, @stevewoodruff and Silja aka @whydotpharma

Until next time...

Good Luck and Good Job Hunting!!!!!!!

 

Science Magazine Survey: American Life Sciences Companies are Some of the Best to Work for in the World

An annual survey conducted by Science magazine and the American Association has identified the 2008 top twenty life sciences employers in the world. The rankings were based on a company’s leadership, stability, social responsibility and treatment of its employees. Six of the top 10— Genentech, Gilead Sciences, Genzyme Corp., Schering-Plough Corp., Gilead Sciences are based in the US whereas the remaining four—Boehringer Ingelheim, Roche Pharmaceuticals, EMD Serono, and Millennium are headquartered outside of the US. For the first time, eight of the top 20 are located outside the United States.

In case you were wondering, Genentech was ranked number 1. This is the fifth time out of the past 6 years that the San-Francisco based company made it to the number one slot (it fell to second last year). Another notable is Massachusetts-based Genzyme which made it to the number 3 spot (out of 575 companies) for the second consecutive year. Surprisingly, Monsanto, the company that makes genetically modified seed crops, was number 2—this despite all of the negative press about genetically modified foods. Let see whether or not Genentech can retain its number 1 ranking after the Roche takeover of the company is completed.

Until next time....

Good Luck and Good Job Hunting!!!!!!!

 

New Webinar and Conference Offerings from Next Level Pharma

NextLevel Pharma has organized several life sciences meetings that may be of interest to BioJobBlog readers. These include: a webinar entitled “Safety Biomarkers in Drug Development” on October 14 and 21, 2009; a conference, “Best Practices in Phase IV Clinical and Observational Research” December 3-4, 2009 in Prague, Czech Republic and “Advancing Biologics from the Lab to the Clinic", January 11-12, 2010 in Brussels, Belgium.

Each of these offerings offers ideas and insights into important issues that are emerging in the life sciences industry. Check it out!

Until next time....

Good Luck and Good Job Hunting!!!!!!!

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Pharma Downsizing Update: More Pink Slips at Eli Lilly & Co

Eli Lilly & Co announced today that it is eliminating another 5,500 jobs or roughly 14% of its global workforce over the next two years. This would reduce to size of Lilly’s worldwide workforce from 40,500 to 35,000 by 2011. In addition to the job cuts, the company is reorganizing itself into 5 business units and hopes to save about $1.0 billion in annual costs.

These newly announced job cuts come after the company eliminated 4,000 sales representative jobs this past August and restructured its sale force. Also, prior to the recent cuts, Lilly launched the Lilly Phenotypic Drug Discovery Initiative or PD2 a new program to ostensibly strengthen relationships with academic institutions to speed drug discovery and thereby reduce its reliance on internal drug discovery efforts to keep its pipeline full.

Unlike other major pharmaceutical companies that conducted massive layoffs over the past two years, Lilly was content, until the past few months, to lay off small numbers of employees and offer others retirement packages. Unfortunately, the loss of patent protection on several of its blockbuster drugs coupled with generic encroachment on several brands and impending health care reform, forced Lilly to take more draconian action.

Layoffs have been something of rarity in the life sciences sector over the past eight months or so, but this is usually the time that marks the beginning of the corporate “layoff season.” Don’t be surprised if other large life sciences companies announce similar layoffs in the coming months. Luckily, the economy seems to be improving and there are signs that hiring is beginning to ramp up in the pharmaceutical, biotechnology and devices industries.

Speaking of pink slips, those of you who have been downsized or find yourself out of a life sciences job may be interested in a new organization called Pink Slip mixers. According to a description on the group’s website:

“Our Pink Slip Mixers are about hundreds of professional, mid- to upper-level executives who are (might be) victims of the "economic downturn" of 2008. Our parties are about banding together, networking and bonding with the recently "Pinked". We will share our experiences of why we were let off, what companies are hiring, and the "buzz words" that specific hiring managers want to hear. Aside from the usual imbibing, commiseration and fun that every pink slip party brings, headhunters, direct-hire companies, and recruiting firms will also on-hand to learn a little bit more about what you do. Maybe you'll meet a new contact, or find a new job!” 

Sounds like these mixers might be good networking opportunities and a place to kick back and commiserate with others who are no longer gainfully employed. I am planning to attend a Pink Slip Mixer when one is organized in the NYC metropolitan area. Like many of you, I lost my full time contract copywriting job over a year ago!

Until next time...

Good Luck and Good Job Hunting!!!!

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Upcoming Next Level Pharma Conferences: Outsourcing Clinical Drug Development

The increasing costs of conducting human clinical trials and the requirement for more stringent safety data for new molecular entities is forcing a growing number of pharmaceutical and biotechnology companies to outsource clinical development of new drugs to Central and Eastern Europe and Asia, most notably India. If your company is considering this option, you may be interested in attending an upcoming conference and workshop sponsored by Next Level Pharma. 

 “Clinical Outsourcing Alliances in Central & Eastern Europe” is a one day conference that will be held on October 8, 2009 in Boston, MA. Company representatives from American and European life science companies and clinical research organization will present talks on the “nuts and bolts” of setting up and conducting human clinical trials in Europe.

A half-day workshop entitled “Clinical Outsource Alliances in India” is being offered on day 2 of the conference. The workshop is intended to introduce American clinical trial sponsors interested in conducting human clinical trials in India to prospective Indian CROs. Presentations from American pharmaceutical executives and Indian CRO representatives will describe the realities of running clinical trials in India and allow attendees to identify potential clinical development partners.

Don’t miss this opportunity to learn the “ins” and “outs of outsourcing foreign clinical drug development.

Until next time...

Good Luck and Good Job Hunting!!!!!

Managing Emotional Fallout After Losing a Job

Losing a job is a BIG deal whether you were layed off, fired or right-sized out of it. Not only do you have to worry about health insurance, bills and paying rent or making a mortgage payment, you must also deal with a myriad of self esteem and emotional issues that frequently arise after losing a job. While there are many articles and books that describe how to functionally conduct a job search after being layed off, there are only a handful that discuss how to cope with the stress and negative emotions that frequently accompany job loss.

Many people who lose their jobs frequently experience emotions like anger, desperation, hopelessness and even depression. These feelings must be acknowledged and then addressed and managed because they not particularly useful when looking for a new job. Further, when left unattended, these feelings can exact both a financial and an emotional toll on the unemployed.

In this Sunday’s New York Times, Phyllis Korkki, who writes “The Search” column describes how to manage the negative emotions and financial problems commonly associated with losing a job. She also provides tips on how to minimize “the pain” and accentuate the positive after experiencing a job loss.

Until next time...

Good Luck and Good Job Hunting!!!!

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Podcast: Putting Social Media to Work for Pharma

Lisa Roner, blogger and editor for EyeforPharma, recommends a podcast on social media that was created by Dr. Andree Bates, CEO at Eularis, a company that applies analytics to determine the sales impact of specific marketing programs.

Dr. Bates says it is an important area for pharmas to become engaged in social media.  In the podcast, she offers some ideas about how pharma marketers might apply these channels effectively. Also, she offers some tips and hints for intrepid pharma employees who are interested in getting started.

To listen to the podcast click here.

Until next time...

Good Luck and Good Networking!!!!!!!!

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Why Bioscientists Aren't Warming to Social Media

BioCrowd co-founder, Vincent Racaniello, and I were chatting the other day with Crowdvine’s Tony Stubblebine (the guy who created the BioCrowd software platform) about the reluctance of scientists to embrace social media. Both Vincent and I, both scientists ourselves, posited that scientists are simply asocial or at the very least not comfortable engaging in social activities whether they be online or IRL. Tony, a self-anointed software geek, wasn’t buying into to our argument and noted that even software geeks are social!

This prompted me to do a little research and I found a blog post written by Nachiket Vartak a blogger and doctoral student at the Max Planck Institute for Molecular Physiology. While the blog post focused mainly on reasons why bioscientists won’t use Twitter, I think that many of his observations can be used to generally describe the chilly relationship between many scientists and social media. Before you read on, I must inform you that I paraphrased and embellished some of Nachiket’s original ideas on the subject. That said, here are some of the reasons why bioscientists may not use social media.

1. The reputation of social networking sites
Many scientists disdain social networks because they believe that social networking sites and microblogging platforms like Twitter are nothing more than places to waste time. Those scientists who use social media usually do it in-between experiments and when planning activities which usually involve copious quantities of alcohol, for after laboratory hours fun. In other words, social media is for fun not for work. Also, many so-called serious scientists contend that “real science discussions” only happen on closed e-mailing lists or forums and not in the “open” on social networking sites.

2. The social activation barrier
According to Nachiket, the stereotype that scientists are asocial is well.....err...true! He asserts that many scientists feel more comfortable focusing on themselves (and their research) rather than interacting with others to learn what they have to say or what they may be thinking. And, many times, unless an individual can demonstrate that they are “smart” they probably aren’t worse listening to anyway. Finally, scientists train for years to become independent investigators. Not surprisingly, there is very little emphasis and importance placed on teamwork or social interactions with others scientists or lay people for that matter. Therefore, it should come as no surprise that many scientists aren’t particularly social or inclined to participate in extracurricular social activities.

3. Privacy aka “secrecy”
Science is a highly competitive endeavor and, in many cases, the discoveries that are made represent many years of sacrifice, blood, sweat and tears. With this in mind, nobody wants to be scooped or beat out by their competitors. Consequently, scientists are generally instructed to be very hush-hush when it comes to sharing any information or data that might give the competition a “leg up” in the competition. Any leak, large or small, could mean the difference between fame and failure and, perhaps more importantly, a successful career as a scientist.

In marked contrast, the success of social media is contingent upon its openness, sharing and transparency. Thus, as Nachiket aptly pointed out social media is antithetical to the very nature of science and scientists.

4. Legitimate channels of communication
The only acceptable and legitimate means of scientific communications are presentations at meetings and publications in peer reviewed journals. These forms of communication are the lifeblood of scientific community and critical to the success of all scientists. If you aren’t published, you have no credibility as a scientist. The scientific publishing and communication industry is big business and “the rules of engagement” in the industry have been well established and institutionalized. Unfortunately, social media threatens to destabilize the science publishing world both financially and philosophically and possibly change the way science information is communicated. Therefore, it should come as no surprise that there is little support for social media in scientific publishing world and the science community in general.

While the number of science blogs and podcasts continue to increase daily, scientific social networking sites continue to struggle. This is because the information flow in blogs and similar forms of social media can be easily monitored and controlled. This is not the case for social networking sites like BioCrowd and microblogging platforms like Twitter.
However, if scientists are truly asocial beings then none of the existing science social networking sites will gain traction and be successful. Call me crazy, but I think social networking is an ideal medium for scientists to exchange information, ideas and develop relationships that can help them jumpstart their careers!

Until next time...

Good Luck and Good Networking!!!!!!!!!!


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The Who's Who of Scientists on Twitter

Berci Meskó author of the Science Roll blog recently compiled a list of sites that keep track of the scientists who use Twitter. He recommends: Science Pond (real time), Sciencebase (compilation) and for those of you with a medical bent the Medical Student Blog (compilation). And, for a list of medical journals that are tweeting check out this site. While the lists aren’t comprehensive you might be able to find friends, colleagues and journal editors who use Twitter.

Hat tip to Berci!

Until next time...

Good Luck and Good Tweeting

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Back By Popular Demand: Resume Writing for Scientists

Like it or not, writing a carefully-constructed resume or curriculum vitae (as resumes are known in scientific circles) is a vital part of any successful job search. Inexperienced job seekers tend to hastily craft resumes without paying much attention to format, style or content and then wonder why they can’t land job interviews. The best way to approach resume writing is to think of a resume as a work of art–something that requires a lot of thought, creativity and attention to detail. As one well-known professional recruiter and job search expert put it”Trying to find a job without a smart, well-crafted resume is like showing up for dinner at a fancy restaurant in a T-shirt and cutoffs. They won’t let you in.” 

I think that it is important for job seekers to think of a resume as a personal marketing brochure that will either land a job candidate interviews or turn a job search into a long, arduous and frustrating process.

The primary goal of a resume is to show prospective employers how you are different than other applicants and why you and not they ought to get the job! So, what are the salient features of a winning resume?

Writing tips

Hiring managers, professional recruiters and human resource professionals tend to quickly scan resumes that they receive and make snap judgments. Therefore, your qualifications and personal attributes must “jump off the paper.” This can easily be accomplished by using bold type, headings, underlining, bulleting and varying font sizes–all of which are simple ways to visually call attention to your strengths. Avoid using paragraphs because they are dense and difficult for hiring managers to navigate.

Powerful, action-oriented, emotional words produce a strong, positive impression. Unfortunately, we scientists have been trained to write in the “passive voice.” That said; try to resist using the passive voice as much as possible when crafting your resume–think outside the box!

Job Objective or Summary Statement

I am sure that somebody has told you at one time or another to include an “objective” on your resume. Objectives tend to be boring, vague and passively delivered. Instead, I highly recommend that you craft a vibrant, action-oriented, can-do “Summary of Qualifications” that accurately reflects and highlights why you are a “right fit” candidate for the job. To that end, it may be necessary to craft more than one summary of qualifications if you are applying for several different types of jobs. For example, your summary statement for an R&D job should be markedly different than the one that you would use to land a business development job.

Which of the following examples do you think better positions the job candidate?

Objective: To obtain a research scientist position at a pharmaceutical company

Or

Summary of QualificationsExperienced scientist with expertise in protein purification and microarray technology. Exceptional leadership abilities and outstanding oral and written communication skills. Able to work independently or as part of a multidisciplinary team.

Professional Experience

Resumes can be constructed either chronologically or functionally. Chronological resumes, which are most common, list content in temporal order and should be used for either lateral job moves or when seeking a promotion or looking for a new job to advance your career. When crafting a chronological resume, jobs or work experience must be listed from most recent to past. In contrast, functional resumes offer content based on skills and are most effective for individuals who are seeking career changes. Functional resumes should present your skills in the order of importance for the new career that you are pursuing. 

It is important to stress that only information relevant to the position should be included in a resume. Unrelated job titles or skills can sometimes confuse hiring managers and may cause them to pass on a qualified candidate. As mentioned above, most hiring managers and employers are simply too busy to read all of the resumes that they receive. Resumes that are chosen for further considerations are typically the ones that contain pertinent, job-specific information that is presented in a straightforward and unambiguous manner.

If you switch jobs frequently or have gaps in your experience put the dates of employment in the far right hand column of the resume (we read from left to right so sometimes dates of employment are overlooked) or hide the job-changing by combining or grouping several jobs together to appear as one. Also, employment dates ought to be listed as years; not the exact start and stop dates of employment, e.g., dates should appear as 2001-2002 not July 10, 2001-January 15, 2002.

Tailoring Your Resume

A resume is not just a list of what you have done and where you have been. It is your opportunity to present and highlight the skills that you possess and how those skills translate into making you the right-fit candidate for a particular job. Quantifying or embellishing achievements and using strong, definitive statements elevate and add authenticity to you as a job candidate.

Which of these examples sounds better?

Designed and directed experiments to study Alzheimer’s disease

                                                            Or

Designed and carried out experiments that identified a key protein in amyloid plaque formation

For each position that you apply, it is critically important to list all relevant experience in the order of perceived importance to the hiring manager or employer. Carefully reviewing job descriptions will allow you to quickly and easily identify those things that are most important to the employer. What is seen first means the most! 

When necessary resumes should be tailored so that as many of your skill sets and accomplishments match what was stated in the job description. This means, that it is highly unlikely that you will be able to use the same resume/CV for all of the jobs that you are interested in. To insure success, I highly recommend that you take the time to customize or tailor each resume/CV that you submit to prospective employers.  When I was looking for a new job several years ago, I crafted no fewer than 20 different resumes!

Odds n Ends

Many of you may have heard that resumes should be no longer than one or two pages in length. While this may be the convention for other fields, it is certainly not applicable to CVs or scientific resumes. That said, it is a good idea to limit the length of your CV/resume because, outside of academic circles, nobody has the time nor the inclination to read a CV that is half an inch thick! When I was working as a professional recruiter, it typically took me a minute or less after scanning a resume/CV to determine whether I had identified a “right-fit” candidate. Candidates whose CVs are too long, overly verbose or difficult to decipher rarely make it to the interview stage. I subscribe to the notion that less is more and simple is elegant!

When listing your educational background, I recommend that present your lowest degree first (associate or bachelor) and end with your most advanced degree or educational experience, e.g. postdoctoral fellowships or professional school. The name and location of the institution that awarded the degree and your major or area of expertise should be listed with each. It is perfectly reasonable to list the names of your graduate or postdoctoral advisor in this section (if you think that a mention will help your candidacy). You may also want to include your thesis title if you wrote a masters or PhD thesis. It is not necessary to list the dates that the degree was awarded. By listing the dates that you received your undergraduate and graduate degrees, an employer may be able to deduce your age. While this may not be a bad thing for entry level employees, it may hinder more experienced job seekers from securing new positions.

Membership in professional societies, organizations or clubs should be listed in a section that is separate from your educational background. Any invited lectures or presentations may also be listed under a separate heading. Also, it is important to list any extracurricular activities or specialized skill sets that you think may be relevant to the positions that for which you are applying. For example, letting prospective employers know that you were an Olympic swimmer or president of the debate team may be what differentiates you from other equally-qualified job candidates.

All of your publications should be listed on the last page of your CV in a section entitled Publications.  If you are just starting your career, it is permissible to list along with your peer reviewed publications all of your abstracts, poster presentations, etc. However, if you are mid-career professional, I strongly recommend that you list only peer-reviewed publications, review articles, books and book chapters and eschew the abstracts. Any manuscripts that are “in press” should be listed. That said,  I don’t think that it is appropriate to include “submitted” manuscripts –this signals to prospective employers that you may not think that your publication list is long enough to warrant consideration.

Never send your references to prospective employers unless they specifically ask for them. Simply indicate somewhere on your resume/CV that references are available upon request. For most academic jobs, it is customary to ask for references at the beginning of the application process. For industrial jobs, references are not requested unless an employer is interested in moving forward with specific job candidates.

Finally, it is vital that you understand that your resume is a required first step in the job search process. A carefully crafted resume/CV that indicates to prospective employers that you are the right woman/man for the job will likely get you to the interview stage. After that…it is all up to you.   Look for the next installment of the series on interviewing skills and tips.

Click here to see the wrong way to write a resume and here for an example of one that resulted in a job offer.

Until next time….

Good Luck and Good Job Hunting!!!!!!!!!!!!!

 

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Keeping Your Resume Fresh

While the economy is showing signs of a possible recovery, the unemployment numbers continue to rise. For this reason, it is a good idea to keep your resume as up-to-date as possible. Yes, I know it is a hassle to update and stay on top of you resume especially if you already have a job. However, in these uncertain financial times, you never know when you might be back on the job market. To that end, I highly recommend a piece on refreshing a resume written by Kim Issacs of Monster.com

In her post, Kim provide some insights and advice on how to keep your resume up-to-date--or fresh as we say in the recruiting business--with minimum pain or effort.

Check it out!

Until next time...

Good Luck and Good Job Hunting!!!!!

 

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The Who's Who of Social Media, Pharma and Healthcare

I met Jonathan Richman,the author of the Dose of Digital blog, last week at the BDI Conference (#BDI) on Social Communication and Healthcare in NYC. BTW, for those of you who were unable to attend, you missed an informative and compelling meeting on the status of social media in the pharmaceutical and healthcare industries. Anyway back to Jonathan. He gave a great talk on pharma and social media which prompted me to visit his blog. While perusing Dose of Digital, I came upon a wiki that Jonathan maintains called --what else-- the Pharma and Healthcare Social Media Wiki.” 

It’s a comprehensive, cataloged list of social media initiatives underway at pharma, biotech and healthcare industries. Noticeably absent from the wiki, are social networking sites like BioCrowd that were specifically created for life scientists and other bioprofessionals. Hey, wait a minute, aren’t scientists the lifeblood of the life sciences industry? Would there be a life sciences industry without scientists? Hmmmm....I will have to talk to Jonathan about this!

I highly recommend you check out the wiki if you are a life sciences social media enthusiast!

Until next time...

Good Luck and Good Social Media Hunting!!!!!  

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Bristol-Myers Squibb to Buy Monoclonal Antibody Maker Medarex

Bristol-Myers Squibb (BMS) announced late yesterday that it intends to purchase Princeton, NJ-based Medarex for $2.1 billion. BMS and Medarex were working collaboratively to develop a monoclonal antibody called Ipilimumab as a treatment for late stage melanoma.

The acquisition represents BMS’s public commitment to transform itself into a “next generation pharmaceutical company” with both pharmaceutical and biotechnology products in its arsenal. Last year, BMS bought Kosan Biosciences, Inc a California-based biotechnology company developing novel cancer treatments. Also, as you may recall, BMS lost ImClone to Lilly in a bidding war over Erbitux—a monoclonal antibody-based colorectal cancer treatment that was co-marketed by BMS. 

Medarex was one of the last independent, public, late stage monoclonal antibody development companies in the biotechnology industry. Many of its competitors, like ImClone and Cambridge Antibody Technologies, had already been acquired by big pharma and I was wondering when Medarex would be acquired. I have always held Medarex in high regard and it is a solid and well position company. To that end, I recommended that my mother purchase Medarex stock several years ago telling her that I thought it had a huge upside. Not surprisingly, the stock has been soaring since the announcement; so much so that my mother called me today to tell me how smart I was—go figure.

It is not clear, at present, what effect, if any, the Medarex acquisition will have on the employment situation in New Jersey. Although BMS is headquartered in NYC, it has two large sites in New Jersey, one in Lawrenceville and the other in Plainsboro. As mentioned above Medarex is based in Princeton, NJ. BMS has been steadily downsizing over the past three years and I suspect that there may be more layoffs after the Medarex deal closes.  If there are layoffs, more are likely to occur on the Medarex side of the business.

While I have been critical of some of BMS’ strategic moves in the past, I think the Medarex acquisition is an outstanding one and BMS will likely benefit from it!

Until next time...

Good Luck and Good Job Hunting!!!

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NYC Social Media and Healthcare Conference Update

The “Social Media and Healthcare” conference that will be held on July 23, 2009 in NYC at the Graduate Center of The City University of NY (365 Fifth Avenue at 34th Street) is shaping up to be a great one. At present, over 350 people have registered for the meeting. There are a few slots left if you are interested in attending.

Several BioJobBlog readers have asked whether or not the sessions will be recorder and available online. Steve Etzler, one of the conference organizers told me that Blogtalkradio.com will broadcast and archive the audio from all of the case studies that will be presented during the morning sessions. Unfortunately, the round table discussions won’t be available.

As I may have mentioned, Cliff Mintz, Co-Founder of BioCrowd will be leading a roundtable discussion entitled “Building Social Networking Sites for Bioprofessionals.”

See you on Thursday!!!

Until next time....

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NYC BioBuzz: Social Media and Healthcare Meeting on July 23, 2009

BioJobBlog and BioCrowd along with the Business Development Institute, the Journal of Communication in Healthcare and others are co-sponsoring a meeting entitled “Social Media and Healthcare” that will be held on July 23, 2009 in NYC at the Graduate Center of The City University of NY (365 Fifth Avenue at 34th Street). Topics that will be covered include:  

  1. Managing regulatory and legal issues when planning and implementing social media strategies
  2. Is there a role for social media in President Obama’s healthcare reform plans?
  3. Why real-time social media tools like Twitter are gaining momentum and when it makes sense to use them
  4. How social media has affected crisis communications in the healthcare industry
  5. Selling social communications projects and proving ROI to senior management
  6. Creating and participating in communities to achieve communication, educational and branding objectives
  7. Planning and executing a social communications plan with little or no budget
  8. Building relationships and partnerships with new healthcare media leaders beyond advertising
  9. Best practices for using social communications to connect internally with employees and stakeholders
  10. Tools, technologies, and best practices for monitoring and measuring social communications

The meeting’s agenda features case study presentations and a series of roundtable discussions on social media topics. I will be leading a roundtable discussion called “How to Build a Social Networking Site for Bioscientists.” Approximately 300 senior marketing, communications and media professionals from Fortune 1000, middle market and emerging growth companies are expected to attend from leading pharmaceuticals, medical technology/device companies, managed care providers, hospitals, healthcare media companies, government and nonprofit organizations.  

BioCrowd members can register for the meeting at a discounted rate of $155. Check it out—it will be money well spent!

Hat tip to Steve Etzler at the BDI and Mario R. Nacinovich Jr., Editor-in-Chief, Journal of Communication in Healthcare for organizing this topical and important meeting.

I hope to see you at the meeting next Thursday!!!!

 

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Search Engines for Life Scientists

Over the past few years, a number of search engines designed for the life sciences have appeared. I thought it might be informative for BioJobBlog readers to list some of the more popular ones and how they are used. I want to warn you in advance that this is not a comprehensive list. That said, if I’ve inadvertently omitted your favorite search engine, please feel free contact me or simply list it in the comments section for this post.

Scirus

Searches over 450 million scientific items, and allows researchers to search for not only journal content but also scientists’ homepages, courseware, pre-print server material, patents and institutional repository and website information. This site is owned and managed by Elsevier.

Novoseek

Search engine for biomedical literature in medline, grants and full text publications that will help you to: 1) retrieve meaningful documents related to your search, 2) narrow your search to find results in the relevant scientific journals and 3) identify the most relevant biomedical concepts for your query.

Mednar

Mednar is a free, publicly available medical research run by Deep Web Technologies.

Valdo 

A search engine that caters to all branches of life sciences. VADLO allows users to search within five categories: Protocols, Online Tools, Seminars, Databases and Software.

Life Sciences Search Engine

A customized search engine developed for the benefit of researchers in life science.

ScienceHack

A unique video search engine for science videos.

Intute

Formerly known as BIOME, Intute is a health and life sciences search engine for disease research.

BioScience Website

BioScience Website’s mission is to organize the world's biological science information and make it universally accessible and useful by utilizing the skyrocketing success of the World Wide Web.

BioNotebook 

A biology search engine run by the Pasteur Institute.

NextBio 

A search engine that enables life science researchers to search, discover, and share knowledge locked within public and proprietary data.

BioPages

Australian web portal and life sciences search engine.

Science Bucket

Specialized search engine that filters biology sites.

GoPubMed

Knowledge-based search engine for biomedical texts. It allows users to identify experts in the biomedical field.

Until next time...

Good Luck and Good Searching!!!!!!!!

 

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What Not To Say in Your Resume

Back in the day—when the economy was sound and jobs were plentiful—an adequately written resume with a sprinkling of keywords and strategically-placed human resources clichés were sufficient to get your foot in the door at most companies. However, in today’s troubled economy where unemployment is rampant, there are certain buzz words and phrases that no longer resonate with hiring managers. According to Liz Ryan, an experienced  corporate career advisor who writes for Yahoo Hot Jobs, the following phrases must never appear in a resume if you are a job seeker in today’s market. 

  • Results-oriented professional
  • Cross-functional teams
  • More than [x] years of progressively responsible experience
  • Superior (or excellent) communication skills
  • Strong work ethic
  • Met or exceeded expectations
  • Proven track record of success
  • Works well with all levels of staff
  • Team player
  • Bottom-line orientation

She contends (and rightfully so) if old and tired phrases (like the ones mentioned above) appear in you resume you run the risk of being marked as “uncreative and vocabulary challenged.” Further Ms. Ryan suggests that you “can make your resume more compelling and human-sounding by rooting out and replacing the boring corporate-speak phrases that litter it, and replacing them with human language— things that people like you or I would actually say.” 

This language change is being driven by the informal nature of social media and a growing emphasis on truthfulness and transparency in the business. Nevertheless, well written resumes—with or without buzz words or key phrases—have always been and remain the first step in the sometimes long and tedius process of landing a new job!

Until next time...

Good Luck and Good Job Hunting!!!!!!!

 

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Another Sign That Pharma Companies Will Rely Less on Internal R&D Programs

The drug maker Eli Lilly and Co quietly launched a new website today for a program dubbed Lilly Phenotypic Drug Discovery Initiative or PD2. According to the company, “The PD2 initiative is a unique opportunity for investigators from external institutions to submit proprietary compounds for potential screening in Lilly's phenotypic assay panel. This highly collaborative process is enabled by a web-based application that facilitates efficient transfer of information between Lilly and the investigator. The PD2 screening panel is currently comprised of five modules which are relevant to therapeutic areas of long-term strategic interest, including oncology, neurological disorders, and metabolic diseases. This panel may change over time to reflect additional research interests.”

Company officials believe that program will allow it to evaluate and possibly license treatments from biotech companies and academic institutions "that are never fully evaluated as potential drug candidates." The launch of the PD2 website—perhaps the first of its kind—clearly sends a signal that pharmaceutical companies are reducing their reliance on internal discovery programs to identify prospective new molecular entities and are eager to enter into licensing deals to find and acquire them. 

Membership in the PD2 requires that a legal representative from the investigator's academic institution or biotech company executes a Material Transfer Agreement (MTA). Once the MTA is reviewed and approved by Lilly officials, the institution can create an account. Until that time, use of the site is limited to browsing only. I have no doubt that technology transfer offices at most major universities will be signing up for membership in short order.

I think the PD2 initiative is an innovative and timely one given the massive reductions in R&D jobs that have taken place at many pharma companies over the past two years. Expect other pharma companies to follow Lilly’s lead.

Until next time....

Good Luck and Good Job Hunting!!!!!

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Pharma Flocking to Social Media?

Mark Sendak, a social media enthusiast and author of the Eye on FDA blog, wrote a great post today about an article he saw in the Washington Post entitled “Drug Firms Jockey for Space Online.”

Mark wrote: “Flock?  Flock?  FLOCK?  The only way you could use the term "flock" in connection with pharmaceutical firms and social media is to say that companies are a scared flock of geese.” He goes on to castigate FDA’s Division of Drug Marketing, Advertising and Communications (DDMAC) for a lack of a coherent regulatory framework and guidance for the use of social media in the life sciences industry.

Mark aptly describes DDMAC’s guidance surrounding social media and the pharmaceutical industry this way. “No one knows, and DDMAC apparently makes this stuff up as they go along. That is the kind of Whack-a-Mole game DDMAC plays.  We won't tell you what is off limits, until you do it and then WHACK! Is this anyway to run a pharmaceutical industry?

I am in total agreement with Mark on this issue. Despite the rapid adoption of social media by other industries, FDA has consistently been reluctant to issue any regulatory guidance what so ever on the topic despite assertions to the contrary. Unfortunately, when it comes to social media and the pharmaceutical industry, FDA’s usual approach to regulatory guidance—reactive rather than proactive—is still alive and well. As you may recall FDA previously sent warning letters to no fewer than 14 pharmaceutical and biotechnology companies admonishing them on their placement of product ads on search engine results pages. The fact that 14 different companies received warning letters on this issue reflects the confusion and lack of guidance offered by FDA on social media and the use of Web 2.0 technologies to promote or support the sale pharmaceutical products.

The growing popularity and inevitability of social media suggests that DDMAC officials along with industry representatives must begin to consider crafting a preliminary regulatory framework for its use in the life sciences industry. Like it or not, social media is here to stay!

Hat tip to EyeonFDA!

Until next time....

Good Luck and Good Job Hunting

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Alternate Career Ideas for Life Scientists

After yesterday's post about career planning for life scientists, one of my soon to be former students in the Fundamentals of Bioscience Program aptly pointed out that my readers might have benefitted more if I had, in fact, offered information about alternate career possibilities for bioscientists.  I don't want the student to get too overconfident but I had the same thought immediately after I uploaded the post.  

Rather than modify the previous post, I decided to upload the presentation that I gave to the U Penn Graduate Student Biomedical Association yesterday.  However, as many of my former (or soon to be former) students will tell you, my PowerPoint presentations, while informative, are not as complete as you might think.  To get the real skinny on alternate careers, you will have to attend one of my seminars on the topic where I provide attendees with additional pearls of wisdom and some funny stories about my own journey along an oft times circuitous career path!

Until next time.....

Good Luck and Good Job Hunting

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Changing and Revitalizing Graduate Education in the Life Sciences

Over the past several years, I have publicly called for fundamental changes in graduate education and training for life scientists. To that end, I was delighted to read an OP-ED piece in today’s New York Times entitled “End Universities as We Know It” written by Professor Mark C. Taylor, Chairperson of the religion department at Columbia University. 

In his post, Professor Taylor recommended several fundamental and systemic changes that ought to improve the likelihood that graduate students and postdoctoral fellows find jobs at the end of their graduate education. While some of Dr. Taylor’s ideas are novel and innovative, two in particular; 1) expanding the range of career opportunities for graduate students and postdocs and 2) abolishing tenure and mandatory retirement; are ones that I have suggested many times in the past few years. Rather than paraphrase, I decided to repost what Dr Taylor said about these two very important, seminal issues.

Expand the range of professional options for graduate students

Most graduate students will never hold the kind of job for which they are being trained. It is, therefore, necessary to help them prepare for work in fields other than higher education. The exposure to new approaches and different cultures and the consideration of real-life issues will prepare students for jobs at businesses and nonprofit organizations. Moreover, the knowledge and skills they will cultivate in the new universities will enable them to adapt to a constantly changing world.

Impose mandatory retirement and abolish tenure

Initially intended to protect academic freedom, tenure has resulted in institutions with little turnover and professors impervious to change. After all, once tenure has been granted, there is no leverage to encourage a professor to continue to develop professionally or to require him or her to assume responsibilities like administration and student advising. Tenure should be replaced with seven-year contracts, which, like the programs in which faculty teach, can be terminated or renewed. This policy would enable colleges and universities to reward researchers, scholars and teachers who continue to evolve and remain productive while also making room for young people with new ideas and skills.

For many years now, I have been struggling with the moral and ethical obligations of graduate education. Recently, I came to the conclusion that it is our role as educators to selflessly impart knowledge and training to graduate students and postdoctoral fellows so that they can pursue the careers (and lives) that many have trained for a decade or more. I think Professor Taylor’s view of the role of an educator says it best: “Do not do what I do; rather, take whatever I have to offer and do with it what I could never imagine doing and then come back and tell me about it.” This is the attitude that must be by academicians if America wants to remain competitive in the life sciences.

Until next time....

Good Luck and Good Job Hunting!!!!!!!!

 

Simponi--A New Anti-TNF-alpha Monoclonal Antibody--Garners FDA Approval.

The FDA has approved Johnson and Johnson’s Simponi (golimumab), a new treatment for adults with moderate-to-severe rheumatoid arthritis , psoriatic arthritis, and ankylosing spondylitis. Unlike Enbrel, Remicade and Humira, other anti-TNF-alpha monoclonal antibody products—which require multiple monthly intravenous infusions—Simponi is injected under the skin and requires only a single monthly injection. 

Simponi is intended for use in combination with the immune-suppressing drug methotrexate in patients with rheumatoid arthritis. It also may be used with or without methotrexate for psoriatic arthritis and alone in patients with ankylosing spondylitis, a chronic inflammatory arthritis of the spine.

In clinical trials, patients who received Simponi for one of the three conditions showed improvements in the signs and symptoms common to their form of arthritis.

Like other anti-TNF-alpha monoclonal antibody products, Simponi labeling includes a boxed warning alerting patients and health care professionals to the risk of tuberculosis and serious fungal infections with use of the drug. The most common side effects of Simponi include upper respiratory tract infection, sore throat, and nasal congestion.

I have no doubt that Simponi will provide much-needed relief to patients suffering from immune arthritis. However, I think that the marketing folks at J& J could have come up with a better name—it reminds me of Spumoni (the Italian ice cream) and The Simpsons television program. But, then again, the name is distinctive and easy to remember!

Until next time...

Good Luck and Good Job Hunting!!!!!!!!!!!

 

The Biggest Loser.....Roche!

The New York Times reported today that Genentech’s blockbuster cancer treatment, Avastin, failed to show a significant effect on preventing the recurrence of colon cancer, limiting its utility as an adjunct treatment to treat primary colorectal cancer. While Avastin is already a best-selling cancer treatment, success in this closely watched and highly visible clinical trial could have paved the way to a new uses of the drug, potentially increasing sales by billions of dollars a year.

Avastin had sales of $2.7 billion in the United States alone last year. But it is currently approved only for late-stage colon, breast and lung cancers. For those indications, patient’s lives have been prolonged for up to a few months. The new trial was designed to determine whether or not Avastin could be used earlier in the course of the disease, right after surgery to remove the tumor. The hope of such so-called adjuvant therapy is to prevent the cancer from coming back at all, effectively curing the patient.

While the Avastin failure will have little or no effect on Genentech’s financial outlook, it does call into question whether or not Roche paid too much last month to buy the 44 percent of Genentech it did not already own. Roche has long insisted that its desire to own all of Genentech did not hinge on the results of this trial. And yet, the trial appeared to play a major role in Roche’s months-long negotiations with Genentech.  It appeared that Roche, which had started those discussions last summer, wanted to complete the deal before results of the Avastin trial were announced — on the assumption that a successful trial would have sent Genentech’s stock soaring, possibly putting the takeover price it offered out of reach.  A failed trial, on the other hand, could have pushed down the value of Genentech’s stock. So it now looks as if Roche could have paid less had the results of the Avastin trial come out before it completed the deal.

Art Levinson, Genentech’s former CEO who played hardball with Roche over the course of negotiations, needs to be recognized for his outstanding business acumen. He and other Genentech executives convinced Roche that Avastin sales could quadruple, to $10 billion, by 2015 if the drug could be used for early-stage colon, lung and breast cancers. This possibility induced Roche to raise its bid for Genentech’s outstanding shares from $86.50 to $95 per share. Although Dr. Levinson wasn’t able to fend off Roche’s takeover and is no longer Genetech's CEO, he is likely “laughing all the way to the bank” as the expression goes. And, who said that PhDs aren’t any good at business?

Roche shares were down more than 10 percent on Wednesday, closing at $29.54.

Until next time...

Good Luck and Good Job Hunting!!!!!


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Life Scientists Should Learn To Be More Social If They Want to Find Jobs

While I was at the Experimental Biology meeting in New Orleans, LA this past week I presented a seminar entitled “Using Social Media For Career Development in the Life Sciences.” This was the first time that I presented this talk, and was expecting a large turn out given the popularity of Facebook and more recently Twitter, a microblogging platform.  Much to my surprise only 15 students showed up for the talk—many of whom hadn’t heard of Twitter and were only vaguely familiar with Facebook. Luckily, a few attendees had Facebook profiles and one or two were on Twitter so the talk wasn't a complete bust.  Nevertheless, the lack of interest in this talk was extremely puzzling to me—my other seminars, “Interviewing Tips” and “Alternate Careers for PhDs” were very well attended and I was booked solid for one-on-one resume critiquing sessions during the five days I was in New Orleans.

I started to wonder why bioscience graduate students in their mid to late 20s, many of whom will need to find jobs (postdocs otherwise) in the next few years, weren’t interested in learning how to use social media to advance their careers or conduct a job search.  I thought that the lack of interest in this topic might be explained if a majority of graduate students and postdoctoral fellows were already using Facebook, Linked In or Twitter to network or explore career opportunities. This proved not to be the case, after learning that only a small percentage of students (who sought career counseling) had considered using social media to network or look for jobs. While many had Facebook profiles, most students primarily used them to stay in touch with friends and family—not for professional or scientific purposes. 

The lack of interest in social media for career development  by many of these nascent GenY scientists was confounding. After all, I have been lead to believe that “GenY” is leading the Web 2.0 and social media charge and that aging boomers like me simply “don’t get it.” The fact that I get it and many  GenY scientists, don’t forced me to revisit what I learned about the social behavior of scientists over the past 30 years or so.

First, it is no secret that scientists aren’t the most  socially-adept individuals and when socializing it tends to be very “cliquish” and oft time exclusive.  Second, scientists are notoriously poor networkers and mostly engage in serious networking when alcoholic beverages are involved.  In other words, very little networking takes place in professional and scientific settings with the exception of  conferences and meetings. Finally, and perhaps most importantly, many of the academicians who train scientists don’t understand networking and often don’t offer any career guidance to their students and postdocs. Unfortunately, most academics have little or no understanding of the world outside of academia and, not surprisingly, there is little incentive for them to learn about it—mostly because of the anachronistic tenure system. Further, because PhDs are taught to be independent and self reliant, there is almost no emphasis placed developing social skills during their training.   In fact, many academics believe that being too social is the best way to be “scooped” by their competitors. Paradoxically, there are currently over 30 social networking sites for scientists (including BioCrowd, the career development networking site that and I started). I suspect that many of us who started these sites recognized an opportunity to use social media to bring scientists together on the Web in a less threatening way than IRL. Although several of these sites report high subscription rates, it is not clear how effective they are for networking and career development purposes.

The job market for life scientists has been extremely difficult and competitive for the past five years or so. Academic positions are still hard to come by and the recent downsizing that has taken place in the life sciences industry—about 85,000 jobs have been lost in the past three years— suggest that competition for life sciences jobs will remain fierce for the foreseeable future. Like it or not, graduate programs must begin to provide job counseling and offer career development training to their students and postdoctoral fellows—their lives may depend upon it. 

Until next time....

Good Luck and Good Job Hunting!!!!!!

 

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Going, Going....Gone: Genentech Agrees to Roche Buyout

Late Thursday, after 8 months of difficult and often acrimonious negotiations, Genentech’s board finally caved and agreed to allow Roche to purchase the remaining 44% of the outstanding Genentech shares that it doesn’t already own. The price: $95 per share—less than the $112 per share that Genentech’s board and management team wanted —but better than the $86.50 per share that was tendered last fall.

While Roche contends that it will continue to run Genentech as an autonomously operating business unit, many Genentech employees are dubious. I suspect that many DNA (Genentech’s stock symbol) employees will embrace a “wait and see” attitude before any decisions are made about whether or not to stay at the “new company.” Roche’s greatest challenge will be integrating the two companies without ruining Genentech’s innovative culture and immediately sending its best scientists and management team out the door. Pharma and biotech corporate cultures are very different from one another and many biotech employees find it difficult to adapt to big pharma’s slow-moving and anachronistic approach to drug development. As previously reported, US business operations of both companies will be based at Genentech’s headquarters in South San Francisco, CA rather than in Nutley, NJ, where Roche’s American business is currently based. This is not good news for many of Roche’s Nutley employees. Roche has been trying unsuccessfully for years to jettison the Nutley site and it seems likely now. Don’t be surprised if you see a mass exodus at the Nutley site. All of Roche’s US products will be sold under the Genentech brand.

Roche’s purchase of Genentech, America’s oldest biotechnology company (started in 1976) and considered by many to be the crown jewel of the industry, truly signals the end of an era. Let’s hope that another “Genentech” (and others like it) emerge as the US biotechnology industry continues to evolve in the 21st century.

Until next time...

Good Luck and Good Job Hunting!!!!!

 

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A "Sea Change at Pharma and Biotech": Recapping the Layoffs

For those of you who haven’t been able to keep up with the latest pharma layoffs, I came across an article in the Philadelphia Business Journal that does an excellent job of recapping all of the major life sciences layoffs that have taken place in the past year or so. The recent massive pharma layoffs prompted William Ashton, Acting Dean of the University of the Sciences in Philadelphia PA to say “I was in the pharmaceutical industry for 28 years. I’ve never seen such a sea change as is occurring right now. This is really dramatic.” Further, Dr. Ashton predicted that drug companies will increase their use of contract sales forces (CSFs) and contract research organizations (CROs) to contain expenses and that staffing firms will be the winners.

This led to me to wonder what Dean Ashton has been doing for the past 10 years or so because the life sciences industry has already increased its reliance on CROs and CSFs. A quick perusal of the pharma and biotech employees who lost their jobs over the past few years reveals that a majority of them were in sales and R&D. I don’t know whether or not I should break the news to Dean Ashton, but the future is already upon us—another example of how out of touch academia is with industry in the 21st century.

I think that it is time for industry executives and academicians to begin a serious dialog to determine the type of training that would be appropriate for individuals seeking jobs in the life sciences industry. A failure to do so will likely have a negative adverse effect on the continued growth and future success of the US life science industry.

Until next time…

 

Good Luck and Good Job Hunting!!!!!

 

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Alternate Career Paths: Taking the Road Less Traveled

For the past five years, I have been giving career development seminars that offer graduate students and postdoctoral fellows alternate careers choices (instead of research) for life scientists. The intent of these seminars is to get students who may not be enamored with a possible life long career at the bench (I know that there a lot of you out there) to think about what they really want to do after they complete their graduate or postdoctoral training.

I recently met Jane Chin (on Twitter) who, like me, has had an unorthodox career trajectory for a life scientist. After exchanging several tweets, I learned that we both are microbiologists, Cornell University graduates, entrepreneurs and social media enthusiasts. But, the main reason I am telling you about Jane is that she crafted a fascinating PowerPoint presentation entitled “3 Lessons About Career Life From a Career Nomad” that provides insights into the decisions and choices that she made to shape her current career path. I highly recommend that you take a peek at the presentation—it may help to reduce some future career stress and angst!

Until next time…

Good Luck and Good Job Hunting!!!!!!

 

Science and Education Need Each Other

The relationship between science, education and industry has always been a tenuous one. To learn more about the complexity of this relationship check out this article that was recently published in a local New Jersey business publication.

Until next time…

Good Luck and Good Job Hunting!!!!!!!!!!

 

Pfizer: "We Will Be Laying Off Employees But Not Sure When"

Over the past few weeks, the blogosphere was rife with rumors and speculation that Pfizer would be laying off additional R&D personnel in December. However, it seems that the layoffs have been postponed and nobody at Pfizer seems to know when they will take place. Conventional wisdom suggests that job cuts will likely take place sometime after the holidays, probably in mid -January, 09.

Rod MacKenzie, Pfizer’s worldwide head of discovery research told reporters “Given the complexity of the changes within research, I have concluded that we will not be able to provide that clarity [for the layoffs] or communicate them by the end of the year." I suspect that he knows who will be getting pink slips but is reluctant to make the announcement until early next year because it would look awful if Pfizer lets people go right before the holiday season. 

Call me crazy, but I don’t think that publicizing lay offs (to be determined later) is good for employee productivity and morale. I have no doubt that rumors about the impending layoffs have been circulating at Pfizer for months. Unfortunately for Pfizer, one or more of its employees leaked the information and company executives are in damage control and spin modes. The inability of Pfizer executives to control internal information flow is just another example of why many industry analysts believe that Pfizer grew too quickly over the past decade. Nevertheless, hundreds and perhaps thousands of Pfizer employees will lose their jobs in the not so distant future.

Until next time…

Good Luck and Good Job Hunting (forget Groton, CT)

 

Is the Recession Going to Kill Biotech?

Recently, I have come across posts on blogs and websites reporting on lay offs and cost-cutting measures that are taking place at some biotechnology companies. A good example of this is a post that appeared yesterday on the Fierce Biotech Web Site. The headline read: “New round of layoffs, cost-cutting at biotechs.”  I thought “OMG this can’t be happening—not the biotechnology industry too!”

However, I am happy to report that many  of my concerns were assuaged after I read the post and realized that the reported downsizing was taking place at small companies, most of which were on shaky ground before the recession even began. Some of the companies that were mentioned included: Titan Pharmaceuticals, Pressure BioSciences, Insite Vision, WuXi PharmaTech Cayman and Targeted Genetics—not exactly titans (pardon the wordplay) of the biotechnology industry. 

There is no question that the current economic downturn will hurt some biotechnology companies (mostly because debt financing is so difficult to secure these days). That said, I think that the biotech industry may struggle a bit over the next couple of years but it will survive because it is in much better financial shape than most other American industries. 

It is important to note that the downsizing and cost-cutting taking place at many pharmaceutical companies is based almost exclusively on projected lost revenues that may occur 2-5 years two years from now—when many blockbusters drugs begin to lose patent protection— not on immediate cash concerns (most pharma companies have plenty of cash on hand). Pharma companies began downsizing in earnest about two years ago because they realized that they had gotten too big and their empty pipelines could no longer justify employing large numbers of unproductive employees. In my opinion, the current economic downturn provided pharmaceutical companies with a good excuse to continue to lay off employees, slash costs and maintain their stock prices. 

Many of the companies mentioned in the Fierce Biotech post have been around for 5-10 years and haven’t been profitable since their inception. As a former business partner once said to me “You don’t really have a business unless you have a product to sell and are profitable.” I suspect that many of these so-called biotechnology “companies” will go out of business—not because of the recession—but because they were unable to develop financially-viable products or services.

 Until next time…  

 

 Good Luck and Good Job Hunting!!!!!

 

Looking to Improve Your Business Acumen?--A New Mini-MBA for Biotech

I am frequently asked by life sciences PhDs whether an MBA would improve their chances of finding a job in industry. And, my response is always “maybe— because it depends. I don’t think that getting a traditional MBA really gives you that much of an edge especially if you are an established PhD looking for career advancement or change.  However, if you are a graduate student or postdoc who has already decided that academia is not for you, then getting a certificate or M.S. through an established graduate program in biotechnology (Georgetown University’s M.S. in biotechnology or The New York Center for Biotechnology's  Fundamentals of Bioscience Program) may increase the likelihood of winning a job in industry. This is because hiring managers recognize that in addition to a job candidate’s technical competency, they possess an understanding of the business aspects of the industry—something that is vital for scientists to be successful in the biotech biz.

Recognizing this, Rutgers University recently created a program that they call ‘a mini-MBA for the biopharmaceutical industry’. In contrast with traditional MBA or M.S. programs, the mini-MBA is a 12 week long, degree-granting program that was designed to familiarize students with the nuances and intricacies of the business aspects of the biopharmaceutical program. The good news is that they are actively recruiting students to fill the slots available in their inaugural class. The bad news is that it costs $4,995 to enroll. That said, it may be worth the time to check it out because—in the end—the investment may be worth it!

Until next time…

Good Luck and Good Job Hunting!!!!!

 

Biotech: On the Ropes?

There was an article in today’s NY Times biz section which suggests that the recent financial crisis is starting to have an effect on the growth of the biotechnology industry, once thought to be a recession-proof sector. The article contends that the lack of available institutional cash and venture money is causing extant biotechnology companies to “tighten their belts.” And, if the trend continues, this lack of capital will stifle innovation, which in turn, will threaten and undermine the stability and future of the entire biotechnology sector. While times are certainly tough, the biotechnology industry, in my opinion, is alive and well and will continue to expand well into the 21st century.

It is important to note that many biotechnology companies that are struggling today are publicly-traded companies not privately held ones. Unlike publicly-traded companies, privately-held ones don’t have to answer to millions of shareholders or worry about their price per share on a daily basis.  Further, the expectations for privately held companies are much less than those for publicly traded entities. Based on recent discussions with venture capitalist friends and institutional investment bankers (those that still have jobs) there is still substantial funding out there for start-ups and companies that are trying to advance their products from development into clinical testing. Many of the financially-troubled public companies mentioned in the Times article were struggling (and on the verge of failing) before the recent financial meltdown. The recent financial crisis is simply hastening their demise. The reason why many of these companies are on the brink is that they went public in the late 1990s—a time when writing a business plan on the back of a napkin was sufficient for investment bankers to underwrite a company’s IPO. Unfortunately, many of these companies were little more than research or tool box driven companies whose founders failed to understand that products not technology would make their companies successful. Put simply, these companies should have never gone public in the first place!

Not surprisingly, almost all of the companies cited in the Times article fit the ‘product-less biotechnology company’ profile. For example, Maxygen, a company originally founded as a “molecular evolution” company (that went public in 1999) didn’t identify a lead product until a couple of years ago. Unfortunately, after spending millions of dollars on preclinical development, the company no longer has sufficient funds to move the product into human clinical testing. Late last week, Maxygen announced that it would layoff 30% of its workforce and consider selling itself.

Another example cited in the article is Iceland’s DeCode Genetics, once a high flying genomics and bioinformatics company that regularly made headlines for discovering new genes for cancer, cardiovascular and hereditary diseases. While DeCode has a great genomic and bioinformatics platform (and “did outstanding science”—largely because of the genetic purity of the Icelandic population) it was never able to use its technology to identify a lead therapeutic product. DeCode’s stock price has fallen more than 90% in the last year to 29 cents per share and will likely fail given the horrendous state of Iceland’s banking industry and economy.

The impending failure of many financially-strapped biotechnology companies in the current financial environment should come as no surprise to biologists—is very consistent with Darwin’s theory of natural selection which says “only the strongest and the fittest will survive. To survive in the biotechnology industry, companies must be single-mindedly product-driven. Companies that lack a product focus, in this or future economies will be able to survive for a short while but ultimately they are doomed to fail. That said, while there may be fewer companies as the biotechnology industry continues to evolve, the companies that do survive will undoubtedly be extremely robust and fiercely competitive.

Until next time….

 

Good Luck and Good Job Hunting!!!!!!!!!!

 

A Different Slant on Direct-to-Consumer (DTC) Advertising

I previously posted a piece on BioJobBlog about direct-to-consumer advertising that is used by many pharma and biotech companies to induce people who see the ads to ask their physicians about a “ drug that they heard about on TV.” John Heubusch who runs Writing Frontier.com, read the post and pointed me in the direction of a piece that he wrote on the same topic. His slant on the topic is different than mine but we both reach similar conclusions—DTC advertising needs to be better regulated by FDA.

Until next time… 

Good Luck and Good Job Hunting!!!!

British Biotech is taking a Beating

Despite a recent report heralding the ascendancy of the Welsh biotechnology industry, the majority of biotech companies in Britain are in danger of fading away according to a report in London's  Financial Times. According to the Times; “Over the past year the sector has witnessed a string of high-profile drug failures, share prices have plunged and there have been almost no public listings. The sector is shrinking as private biotech companies are bought by cash-rich pharmaceutical companies, most of which are based abroad”.

“The quality of British science has never been in question. Commercial biotech’s perennial problem, say the pundits, is instead a lack of financing, management expertise and commercial savvy. “The UK has always labored under the yoke of not having enough venture capital around and not having the people prepared to take risks” said one analyst.” Nevertheless, the UK is currently  responsible for more than one-third of the European Union’s total drug pipeline.

The British biotechnology industry isn’t alone. Consolidation of the US biotechnology industry has been quietly going on for the past 5-10 years. Many successful American companies have been acquired by major pharmaceutical companies. For example, MedImmune and Millennium Pharmaceuticals were recently purchased by Astra Zeneca and Takeda Pharmaceuticals respectively. That said, I don’t think that what is happening in the UK is unique to the British biotech industry. The bottom line is this; Biotech is a capital-intensive, briskly paced, risky business that is, at most, 35 years old. More companies than not are expected to fail. Pharma, on the other hand, is a conservative and experienced cash-rich industry that is over 100 years old. Therefore, it follows that pharma companies, when possible, will buy successful biotech companies to bolster their thinning pipelines to stabilize their stock prices.

In my opinion, the seminal underpinning and essence of the biotech industry is to harness scientific originality to create innovative l technologies and products. That said, I believe that the biotechnology industry has finally become an integral part of the life sciences ecological food chain (think of biotech as a producer and pharma as a consumer).  I can’t think of many biotechnologies company executives (with the exception of Biogen) that wouldn’t consider acquisition or merger with a major pharmaceutical company as an ideal exit strategy for their stakeholders!

Until next time….

Good Luck and Good Job Hunting!!!!!!

Personal Branding and Developing an Online Presence

Peggy McKee wrote an interesting piece on her Medical Sales Recruiter blog about personal branding and developing an online presence to find a job. For those of you who haven’t heard about personal branding, it is de rigueur and the hottest thing on the net these days. Put simply, you, the jobseeker, are the brand and to be successful (get a job), the brand must be vigorously promoted! Personal branding can be easily achieved by creating profiles on social networks like MySpace, Facebook or Linked In or creating your own promotional website using your name as the domain name.  However, there are a few things that you ought to consider before you embark on your personal branding campaign. Peggy offers a few pointers and recommendations when it comes to both personal branding and your online persona.

Employers and recruiters research prospective candidates online to get more information about them before an interview is scheduled or an offer is extended.  This can work against you if your MySpace page is filled with “party” pics (or worse), but it can work for you if you have an effective online persona

Web Worker Daily rounds up several tips for developing an effective online presence:

  • Check your Google profile.  What comes up when your name gets typed in?  Know what’s out there so you don’t get suprised.
  • Own your domain name.  Even if you don’t want to do something with it now, you might later.
  • Develop your personal brand.  Set up a LinkedIn profile.  Write a blog.  Be a guest writer on blogs specific to your industry (maybe you could write a post for me - describing your job, etc).   If you’re not sure what personal branding is or how to do it, there’s a lot available out there.  Here’s 3 articles to get you started:

The 6 P’s of Personal Branding (Persona, Positioning, Packaging, Presentation, Promotion, and Passion)

Three Keys to Building a Strong Personal Brand.  “A good brand has 3 main features:  clarity, consistency, and constancy.”

Dan Schwabel’s podcast, Top Social Media Tools for Turning Your E-Brand into a Powerhouse.  Let Dan show you how to choose what to use.

 Until next time…

Good Luck and Good Job Hunting (personal branding can’t hurt)!!!!!!!

More Interviewing Tips

I happened upon this article that expands upon some of the interviewing ideas and tips that I presented in previous posts. The piece was written by someone from Business Week so it must relevant and might even be worth reading! 

Until next time….

Good Luck and Good Job Hunting!!!!!!!!

2008 FASEB Career Development Symposium

I am sitting in Newark Airport waiting for my flight to San Diego which, not surprisingly, has been delayed for about 2 hours.  As you might have guessed from the title of this post, I am on my way to the 2008 FASEB Career Development Symposium which is run every year at the annual FASEB meeting. 

As we have done in the past, my colleagues Eric Celidonio and Joe Tringali, and I  will be presenting seminars and resume writing workshops for graduate students and postdocs.  Our goal, as always is to offer these folks some advice and tips on how to find a job after they complete their training.  Unfortunately, the job market for PhDs has been depressed for the past 8 years or so.  There once was a time, circa 1994-2000, when finding a job for alife sciences or chemistry PhDs was a snap.  In those days, many jobs were left unfilled. Ironically, it  has been scientific advances and technological innovations that have made it more difficult for PhDs to find jobs over the past decade or so.

Anyway, if you are attending FASEB this year, please stop by.  Also, tell all your friends!  We like when it is busy.

Until next time....

Good Luck and Good Job Hunting!!!!!!!!!!

Part 6: Ask the Recruiter--Preparing for a Face-to-Face Job Interview

The hard work you that invested in your resume has finally paid off–you just received a call from the ACME Biotech’s Human Resources Department inquiring about your availability for a face-to-face interview with the company. After about 30 seconds of elation and joy, fear and anxiety begin to creep into your psyche-“OMG, an interview, this is my first one, what am I going to do?” 

As you all should know by now, a job interview is typically the pivotal event in any job search. Your performance on a job interview will likely be the different between a job offer or not. That said, you must be adequately prepared for all of yourjob interviews (even the ones that you think you don’t want) if you expect to receive job offers. Unlike stand-up comedy where improvisation has its place, ad libing or “shooting from the hip” during a job interview is dangerous and can yield disastrous results. Like everything else in life–practice makes perfect! So how does one prepare for a productive and successful job interview?

Scheduling An Interview

Typically, during your initial phone call, an HR representative will offer you several dates and times for an interview. I highly recommend that you refrain from verbally accepting the first date and time that the representative offers. Instead, thank him/her for the proffered dates and times and indicate that you will get back to them shortly regarding your availability. It is wise to use this approach because, at this stage of the job search process, there is a huge imbalance in the relationship between an employer and job candidate. Put simply, at this point, the employer has the power–without an offer you cannot work at the company! By delaying your response, you are signaling to the company that you (like their employees) are a busy person with a full schedule. Further, it suggests to a hiring manager that you may have other job interviews and that you’re “not desperate” for the job. Whether your level of desperation is high or low is irrelevant. The purpose of this tactic is to attempt to tip the balance of power in your favor–something that will be important in negotiations if a job offer is extended.

After you have decided which of the proposed interview dates and times is most convenient for you, call the company back to schedule the interview. Obviously, if there are scheduling conflicts surrounding the date that you chose, you must be flexible enough to accommodate the company. If your interview requires air travel, I highly recommend that you arrive a day before your interview. Arriving the evening before is okay but if you flight is delayed or cancelled you may be out of luck! Likewise, if the interview requires that you drive more than 2 hours, I highly recommend that you arrive at the interview destination the evening before. Again, if you wait until the day of the interview to travel, heavy traffic, weather conditions, road closures or car problems may prevent you from arriving to your interview on time.

Interview Preparation

Once the interview date has been scheduled, you must begin to prepare, in earnest, for the actual face-to-face. This will require a fair amount of work on your part. That said, you must allocate a sufficient amount of time from your otherwise busy schedule to accomplish this task. Leaving it to the day before your interview is not a good idea!

First, you must thoroughly research the company to find out: 1) what they do, 2) how they do it and 3) who is in charge. A facile way to accomplish this is to visit company websites, read press releases and blog posts and chat with current or former employees. Another way, if the company is publicly traded, is to read a company’s annual stock holders report. 

Typically, during a job interview, you will meet and chat with a variety of individuals ranging from co-workers to managers to company executives. It is vitally important that you craft a list of questions that you can ask all of interviewers that you will meet. This signals to a prospective employer that you “did your homework” and that you are interested in the job that you are interviewing for. It also provides them with insight into your work habits, skill sets and the level of detail that you might bring to the company if you are offered a job. If you don’t ask any questions, it might appear that you are not seriously interested in the job or the company. Nevertheless, it is critically important to remember that a job interview is a fact finding mission for the both the company and job candidate. Both parties need to be convinced that they are a fit before a job offer is extended.

I have listed below several questions that you might ask various individuals during a face-to-face job interview:

Hiring Manager (your future boss)

  • What are the most important skills for the job?
  • What type of person are you looking for?
  • What is the typically career path for individuals hired into this position?

Company Executives (the big kahunas)

  • Why does this company have an edge over competitors?
  • Where do you see the industry moving in the next five years?
  • When do you anticipate that your lead product will hit the market?
  • What are the company’s biggest challenges and how will the company meet them?

Coworkers (the guys in the trenches)

  • What is a typically day like for you?
  • What is the company culture like?
  • What do you like most about your job?
  • What challenges do you face at the company?

In addition to the questions that you will ask, you must prepare answers to a serious of questions that company representative will undoubtedly ask you during your interview.   I will cover those in my next post.

Interview Appearance and Wardrobes

Surprisingly, choosing what to wear for an interview is not as easy at it might seem. The bioscience industry is a very conservative one–not as traditional or “stuffy” as the banking industry but not as free-wheeling at the advertising biz. When in doubt, it is better to trend toward the conservative rather than the flamboyant. Like many other things in life, interview appearances and wardrobe choices are much simpler for men than women. Listed below are some of my recommendations on how to look and what to wear on a job interview.

For Men 

  • Always wear a sports jacket or suit and tie to the interview and dinners that you may attend (never wear shorts, blue jeans or other informal attire)
  • Get a haircut
  • Shave (unless you have a full beard) the morning of the interview
  • Don’t wear an overpowering deodorant or cologne
  • Make sure that your shoes are polished and match your outfit (do not wear sandals or Birkenstocks)
  • Take off your earrings, nose studs and other piercings
  • Cover all tattoos and other body art

For Women

  • Wear a suit (with pants or skirt)
  • If you wear a skirt, make sure it is an appropriate length (miniskirts may get you looks but usually not the job)
  • Don’t wear low cut blouses (again, you might get looks but not the job)
  • Wear an appropriate amount of make up
  • Decide on a hairstyle (don’t wait until the morning of the interview to decide!)
  • Make sure that your shoe choice is appropriate (4”-6 “heels may not be a good idea)
  • Wear a subtle (not overpowering) perfume
  • Don’t wear nose studs or rings or other piercings (earrings are, of course, acceptable)
  • Cover all tattoos and other body art

Look for my next post on interviewing to learn how to behave, act and react on the day of your interview!!!!

Until next time….

Good Luck and Good Job Hunting!!!!!!!!

What to Look For in a "Bad" CEO

According to Terry Leap, a Professor of Management at Clemson University, CEOs that exhibit some or all of the following traits or behaviors are likely to be problems.

  • An obsession with acquiring prestige, power and wealth
  • A reputation for unwarranted and shameless self promotion
  • A tendency to propose “grandiose strategies” and failing to include a detailed plan to carry them out.
  • A superb ability to compartmentalize and rationalize things.
  • A history of emphasizing activity, like hours worked or meetings attended, over accomplishment.
  • A reputation for implementing major strategic changes unilaterally or for forcing programs down the throats of reluctant managers.
  • An impulsive, flippant decision–making style.
  • A love of monologues coupled with poor listening skills.
  • A tendency to display contempt for the ideas of others.
  • A penchant for inconsiderate acts

The thing that worries me is that many academicians and most CEOs that I know exhibit five or more of these traits. Oy! 

Until next time…

Good Luck and Good Job Hunting

GPC Biotech Slashes More Jobs

Germany’s GPC Biotech announced another round of job cuts as it tries to regroup after its failure to win US approval of its experimental prostate cancer drug satraplatin.

The company said that this latest restructuring will sharpen its focus on oncology clinical development efforts and further reduce costs to extend its cash reserves to cover three years of operating expenses. The restructuring is mainly focused on GPC’s early-stage research activities in Munich and will result in 38 job losses. The remaining work force will be 14 in Munich and 49 in Princeton, New Jersey. These latest cuts come after an announcement in November that the firm was slashing its workforce by over 100.

A GPC Biotech spokesperson also announced that the company is discontinuing internal development of the 1D09C3 monoclonal antibody, which is in Phase I clinical trials for relapsed/refractory B-cell lymphomas. However, RGB-286638, a broad-spectrum cell cycle kinase inhibitor, is expected to enter the clinic within the next six months. 

Things are looking pretty dicey at GPC Biotech.

Until next time….

Good Luck and Good Job Hunting!!!!!!!!!

Just As I Suspected!!!!

I want to thank Ed Silverman over at Pharmalot for providing me with data to back up my suspicions that hiring is taking a downturn at most pharmaceutical, biotechnology and medical devices companies.

According to the post at Pharmalot “Employers and recruiters in pharma, health care and biotech performed fewer searches in October, mostly thanks to declines in two key states - New Jersey and Massachusetts, which dropped by 5.6 and 3.2 percent, respectively, according to stats from MedZilla.com. Of the top jobs posted, the biggest changes were in research (a loss of two percent) and gains of 1.8 to 2.3 percent in business development, primary care, and marketing. Applicants, meanwhile, continued at the previous month’s rate of job searching, with only California seeing a change of more than one percent in either direction.”

Sales jobs are also taking a big hit.

I hate to be the bearer of bad news but sometimes a reality check is necessary to maintain perspective.

Keep the faith!

Until next time…

Good Luck and Good Job Hunting!!!!!!

Pharmalot