Merck's Best Days May Be Behind It....Again

Oh, what a difference a couple of years or results from a pivotal clinical trial can have on a company’s financial outlook. As you may recall in 2005, Merck was in a shambles after the Vioxx scandal broke. Its CEO was ousted, its stock was trading at less than $35 per share and employee morale was at an all time low. After two short years, Richard Clark, a life-long Merck employee, was able to turn the company around. Merck’s stock reached a high of almost $61 last December and many of its employees were dancing in the streets of Rahway because their stock options were now worth more than the paper that they were printed on. But, like many things in life, all good things must come to an end.

Since December Merck’s stock price has plummeted to $40 and appears to be headed downward. What sparked the retreat was the release of results from the now infamous ENHANCE clinical trial which showed that Vytorin, which is co-marketed by Merck and Schering Plough, offered no greater benefit than a cheaper, generic version of Zocor (one of the two active ingredients of Vytorin) to reduce the risk of heart attack and stroke. The fallout from this revelation has been intense and dramatic. Both Merck and Schering Plough are being investigated by Congress for marketing violations and the financial maneuvers’ of several senior executives from both companies are under intense scrutiny. 

Many industry analysts believe that Merck may be on the ropes again and are afraid that the company may slip back into the morass it found itself in after the Vioxx debacle.

I have always held Merck in high regard–no fewer than 15 people who I went to graduate school have worked at Merck at one time or another. Further, the Merck name used to be synonymous with “second to none” science and outstanding pharmaceutical products. Sadly, over the past decade Merck’s leadership has consistently placed profits before good science causing the American public to lose confidence in one of its flagship pharmaceutical companies. Maybe Dick Clark, who was around during Merck’s glory days, can restore Merck’s reputation by insisting that from now on, good science will always come before corporate profits. Time will tell….

Until next time….

Good Luck and Good Job Hunting!!!!!!!

What to Look For in a "Bad" CEO

According to Terry Leap, a Professor of Management at Clemson University, CEOs that exhibit some or all of the following traits or behaviors are likely to be problems.

  • An obsession with acquiring prestige, power and wealth
  • A reputation for unwarranted and shameless self promotion
  • A tendency to propose “grandiose strategies” and failing to include a detailed plan to carry them out.
  • A superb ability to compartmentalize and rationalize things.
  • A history of emphasizing activity, like hours worked or meetings attended, over accomplishment.
  • A reputation for implementing major strategic changes unilaterally or for forcing programs down the throats of reluctant managers.
  • An impulsive, flippant decision–making style.
  • A love of monologues coupled with poor listening skills.
  • A tendency to display contempt for the ideas of others.
  • A penchant for inconsiderate acts

The thing that worries me is that many academicians and most CEOs that I know exhibit five or more of these traits. Oy! 

Until next time…

Good Luck and Good Job Hunting

Can Scientists Be Effective CEOs?

Over the past 30 years or so, the vast majority of chief executives in the drug business have made their way to the top via the sales and marketing departments. Few senior executives have toiled in a research laboratory or for that matter, know the difference between NMR and protein purification. However, things may be changing in the industry. A quick perusal of the CEOs of the top 20 pharmaceutical and biotechnology companies (see below) reveals that 11 of 20 have degrees in engineering (4), medicine (2) and science (5). The remaining 9 have degrees in business and finance (3), sales and marketing (4) or law (2). Several of the scientists (2), engineers (3) and one physician also earned MBA degrees.

 

Conventional wisdom suggests that scientists usually do not make good CEOs (they are not formally trained in business). However, doesn’t the lack of scientific sensibility put non-scientist CEOs at a disadvantage when it comes to making strategic and operational decisions about R &D?  One would think so….!!!!

 

A careful examination of my top 20 list suggests that some of the most successful companies are run by scientist CEOs, e.g. Genentech, Gilead, Novartis and Lilly. Expect to see more scientist CEOs at large biotechnology and pharmaceutical companies in the future–R&D have become way too complex for non-scientist to truly understand its nuances and potential pitfalls. Plus, we scientists know that obtaining a MBA degree is a “piece of cake” as compared with the PhD degree! Hmmm, I wonder what business people think about PhDs?

Company

Name

Background

2006 Total Compensation

Abbott

Miles White

Mechanical Engineering and Business (MBA)

$26,915,358 

Amgen

Kevin Sharer

Aeronautical Engineering and Business (MBA)

$34,390,000

AstraZeneca

David Brennan

Sales and Marketing

$4,226,000 

Biogen/IDEC

James Mullen

Chemical Engineering

$1,450,000

Bristol-Myers Squibb

Jim Cornelius

Business (MBA) and Finance

$1,472,879

Eli Lilly

John Lechleiter

Chemistry (PhD)

Not available (newly appointed)

Genentech

Arthur D. Levinson

Molecular Biology (PhD)

$17,124,025 

Genzyme

Henri A. Termeer

Finance and Business (MBA)

$36,380,000

Gilead

John C. Martinis

Organic Chemistry (PhD), Chemical Engineering and Business (MBA)

$22,860,000

GlaxoSmithKline

JP Garnier

Pharmacology (PhD) and Business (MBA)

$5,413,000 

Johnson & Johnson

William C. Weldon

Sales and Marketing

$28,557,749 

MedImmune

David Mott

Banking and Investment

$11,411,897

Merck

Richard T. Clark

Business and Marketing (MBA)

$10,236,740

Millennium

Deborah Dunsire

Physician (MD)

$3,874,464

Novartis

Daniel Vasella

Physician (MD) and Business (MBA)

3,199,505 CHF

Pfizer

Jeffery Kindler

Lawyer

$9,799,233 

Roche

Severin Schwan

Lawyer and Finance

Not available (newly appointed)

Sanofi Aventis

Gerard Le Fur,

Pharmaceutical Sciences (PhD)

Not available (newly appointed)

Schering Plough

Fred Hassan

Chemical Engineering and Business (MBA)

$5,790,000

Wyeth

Bernard Poussot

Business and Finance

Not available (newly appointed)

Until next time….

Good Luck and Good Job Hunting!!!!!!!!