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Mary Canady author of the Comprendia Blog recently analyzed the popularity (or lack thereof) of a number of social networking sites that were created for life scientists. It would seem that online social networking sites would be ideal for scientists because we are not known for our networking or social communication skills in real life. However, only a few of the more than 15 life sciences social networking sites started in the past two years are doing well based on the traffic and usage statistics cited by Mary in her post. 

While Mary’s analysis included most of the well known life science social networking sites, she failed to include BioCrowd, the networking site started by Vincent Racaniello and me. While BioCrowd does cater to life scientists, we intentionally expanded our network to include other bioprofessionals including medical writers, marketers, consultants, venture capitalists and even CEOs! After all, it takes a village to take an idea from concept to commercialization.

Hat tip to Mary for the insightful post!

Until next time...

Good Luck and Good Job Hunting!!!!!!!

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Mark Senak who writes the EyeonFDA blog has compiled a list of the life sciences companies that presently have a Twitter account and use it. While there are only 12 companies on the list, he provides a nice commentary on their use and makes some recommendations for improvement.

Although I am a staunch supporter of the use of social media in the life sciences, it appears to me that the discussion about its use has been somewhat muted since the FDA convened a public hearing on the topic last month. I suspect that many of the companies and stakeholders who participated in the discussion prior to the FDA meeting are presently in “wait and see” mode. However, don’t be surprised if the social media guidance issued by FDA is lacking and excruciatingly wanting!!!! For those of you who may not be familiar with the ways in which the agency operates, its regulators tend to craft guidance and regulation that are broad, loosely defined and open to interpretation. The agency intentionally crafts its guidance and regulations this way because it doesn’t want its rules and regulations to be “literally interpreted” by companies and other stakeholders. Generally speaking, its regulations represent the “minimum” requirements that must be met in order to insure regulatory compliance. In other words, there is no upper limit on what companies can do to insure compliance but there certainly is a minimum requirement that must be met to avoid regulatory sanctions and penalties. As one lawyer who used to work for the agency shared with me recently, “FDA crafts the regulations but it is left to the companies and courts to interpret them.”

Most of the current discussions about social media and the life sciences industry primarily focus on its use as marketing and promotional vehicle. And, as many of you may already know, FDA isn’t exactly keen or pleased with the current marketing and advertising strategies and practices utilized by a sizeable number of life sciences companies. Perhaps a shift away from marketing and advertising discussions to more regulatory-friendly and practical applications like clinical trials recruitment and public outreach may lead to a more rapid uptake of social media by FDA and life sciences companies? Just sayin’

Until next time...

Good Luck and Good Tweeting!!!!

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Amber Johnson of Accredited College Online thought that BioJobBlog readers might be interested in an article that she authored entitled “10 Big Ways that the Recession is Hitting Higher Ed.”  It is an informative piece that might be of interest to high school and undergraduate students and parents who have kids in college.

10 Big Ways the Recession is Hitting Higher Ed

From elementary to college, schools around the nation have felt the recession in many different ways. As the economy sinks, the educational demands rise. Teachers are holding on to dear life for their jobs, students are struggling to pay for college and the states are running out of school funding. But even with all of these economic woes, there are still people eager to teach and happy to learn.

1. Budget Cuts. Since the beginning of the fiscal year, the U.S. has suffered a 5 percent drop (about $4 billion) from the amount of money state governments apportioned for higher education, according to a U.S. News & World Report article. This is directly affecting universities across the country, who’ve seen larger class sizes, less professors and counselors, as well as canceled courses, which experts say could "threaten the quality of education."
2. Spike in Tuition. College tuition has been an inevitable hurdle for many students and families for years, but in this recession, it stings that much more. Since 1982, college tuition and fees have increased 439 percent, which is about three times higher than the increase in family incomes, according to an ABC news report. In some cases, tuition increases are the school’s response to more financial aid requests, but these scholarships may not be enough to cover soaring prices.
3. Decline in Aid. Many states are cutting college financial aid programs when students need it most. An increase in unemployment and financial losses has caused 620,000 more students to apply for federal aid in the first quarter compared to last year. An Associated Press article reports that without financial assistance, students may be forced to drop out, transfer or be laden with debt.
4. Decline in Endowments. A major factor in these educational downturns is the decline in college endowments. Big and small donors simply aren’t giving back right now, which has caused hiring freezes, cutbacks on financial aid and halted construction projects, according to a Wall Street Journal article.
5. Graduate in Three Years.Graduating in three years is a surefire way to slash college costs. American colleges are now starting to offer three-year college degrees, which is the normal time frame for many British and Canadian students. It’s an upcoming trend, according to CBS MoneyWatch, that could make "elite education" more affordable.
6. More Kids Are Going Public. According to a CBS News report, private school enrollments have declined as many students make the switch from private to public schools. While some continue to pay top dollar for private school tuition payments, others have had to transfer to less prestigious schools to save money.
7. Arts Programs Suffer. With devastating budget cuts on the agenda, college art departments are the first area to be altered. According to a New York Times article, students can expect to see fewer teachers, programs and courses in the arts when they return to campus in the fall. While some colleges are phasing out programs altogether, others, like Louisiana State University, are holding off on new computers, production technology and traveling for conferences to lessen their demand for funding.
8. Growth and Decline of Majors. For college students, choosing the right major during the recession may secure a stable career in the future. Certain industries, such as journalism, entertainment and finance should be avoided, according to a report by College Finance 101, because they have seen the most turmoil during the recession.
9. Higher Community College Enrollment. With the recession at its peak, many college students have opted for the more affordable institutions — community colleges, according to The Chronicle of Higher Education. However, this influx of students has caused some community colleges to turn them away, claiming there’s not enough room, teachers and accommodations at these campuses.
10. Distance Learning is More Desirable. A big thing hitting the economy is online education. Whether people have lost a job, are fearful of losing one or want a degree, online colleges have open seats. A CNN report, titled "Riding out the recession in a virtual classroom," touches on the idea of investing in education during troubled times to have a back-up plan and find the right career path for you.

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Despite its humble beginnings in the late 1970s, the biotechnology industry has transformed itself into one of the most vibrant sectors of the American economy. Pharmaceutical companies, once the bell weather of the life sciences industry, have finally conceded that biotechnology and not small molecules are the industry’s future!

While growth of the biotechnology industry has slowed somewhat in the past couple of years—mainly because of the recession—it still represents a viable career option for students interested in the biological sciences. Contrary to popular belief, a PhD degree is no longer required to gain employment in the biotechnology industry. The PhD degree option is slowly being replaced by biotechnology masters and undergraduate degrees and certificate programs readily available at many two year colleges. Put simply, there is a decreasing demand for PhDs at many life sciences companies—mostly because of technological advances and a growing reliance on outsourcing to carry out drug discovery and development. However, the demand for non-PhD employees with solid biotechnology backgrounds particularly in the areas of regulatory affairs, licensing, business development, medical communications, health informatics and biomanufacturing is rising.

For many students (especially high school and undergraduates), the plethora of biotechnology degree and certificate programs can be overwhelming. With this in mind, I came across a cool website called Biotechnology Degree Guide which helps students decide which program is right for them. The site is run by Webster Jorgensen who sent me the following information about the site.

“Biotechnology Degree Guide was developed to be a complete and comprehensive guide for finding colleges, universities and technical schools offering biotech and related programs. The site also features a rating system that allows registered users to rate various biotechnology programs. This feature was added to help separate the great programs from the not-sop-great ones. In the future, we plan to start highlighting "Hidden Gem" programs section that helps schools with lower profiles and great programs receive more exposure. The sites members section is open to prospective students, students, professionals, teachers and biotech hobbyists.  A social media component is planned for the future.”

While the Biotechnology Degree Guide may not answer all of your questions, it certainly is a good place to start when considering a career in biotechnology!

Until next time...

Good Luck and Good Job Hunting!!!!!!!!!!

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The economic crisis is having an adverse effect on enrollment at four year colleges and universities. Most four year institutions are reporting record low enrollments. While things are spiraling downward at many four year colleges and universities, business is booming at two year technical schools and community colleges. Seemingly, this ought to be good news for two year institutions. Unfortunately, statewide funding cuts and faculty shortages are making it difficult for community colleges and technical schools to accommodate burgeoning enrollment.

The rising enrollment at community colleges can almost exclusively be attributed to the current cost of attending 4 year colleges and universities. The cost differential between attending four year institutions and community college is stunning. For example, tuition at Miami Dade Community College, the largest community college in the US, is $1,000 per semester for Florida residents. In marked contrast, tuition at the University of Florida—a public institution— is roughly $5,000 per year and a whopping $42,000 at the University of Miami which is private.

Undergraduates are flocking to community colleges simply because many can’t afford to pay tuition for 4 or more years at most colleges and universities. The new paradigm for undergraduate education is to complete the first two years of college at a community college and then transfer to a 4 year college to finish a degree. Unlike other post secondary education institutions, there are no entry requirements at community colleges—open enrollment is the norm. This means that these schools are obliged to allow anybody with a high school diploma or GED to register for classes. In marked contrast, four year colleges and universities can regulate the size of their incoming freshman classes to deal with financial difficulties. For example, because of budget cuts in Florida, the state's 11 public universities have imposed caps on freshman enrollment. This has put increasing pressure on community colleges in Florida and other stacks to “pick up the enrollment slack.”

While attending community college may be an economical way for students to earn undergraduate degrees, two year colleges have been overwhelmed by the massive enrollment increases. "As it stands right now, we have almost 39,000 students registered for the fall term, and we began fall registration only two weeks ago," says Dulce Beltran, registrar at Miami Dade College. "And a quarter of the courses are already closed with almost two months to go before fall term begins." Not surprisingly, Miami Dade officials say that enrollment is 60 per cent higher than last year’s pace. School officials have been hiring new instructors and adding new courses to handle the enrollment surge.

Unfortunately, school officials estimate that 20,000 to 30,000 students won't get all the classes they need; 5,000 may not be able to sign up for any classes in the fall. Similar scenarios are playing out in other states including Arizona, California, Washington and others. Officials in those states are fearful that hundreds of thousands of prospective new students will be turned away this year.

There is no question that the recession is taking a toll on the ability of American students to attend college. However, the cost of an undergraduate education has been steadily increasing for the past decade. Rising overhead costs, higher faculty salaries and over expansion have all contributed to the increases. Something will have to give soon. Don’t be surprised if the education bubble is the next one to burst!

Hat tip to NPR!

Until next time....

Good Luck and Good Learning!!!!!!!

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I was reading Karen Ventii’s Science to Life blog today and she “turned me on” to a couple of new web-based tools that I think might be useful to people who work in the biosciences. I added Karen’s recommendations to a list that I was building and decided that it had reached enough of a critical mass to share it with you.

The first of these new tools is called graduatejunction.com, a research community primarily aimed at graduate students and postdoctoral fellows. According to its founders—a team of UK graduate students at Durham and Oxford universities—the intent of graduatejunction.com is build a community of graduate students and postdoctoral fellows so that members can stay abreast of research activities within in the community and to connect with other community members who share common research interests. Not a bad idea, considering that many graduate students and postdocs frequently operate in intentional mentor-induced research vacuums.

The second is called labmeeting.com. It is a novel, web-based tool that helps researchers organize (and search) personal PDF collections, share laboratory protocols, Powerpoint presentations and other scientific data with their lab mates. The software was created by graduate students at Stanford University and it aims to organize laboratory research so that it can be conducted more efficiently and at a faster pace (time is money after all). I think that this concept has legs and might be a big winner downstream (although security will be of paramount importance).

Another new tool that warrants praise is biomedexperts.com that was created by Collexis, Inc. In my opinion, biomedexperts.com is the “mother of all” publication search tools and literature management systems. Billed as the first literature-based social network, it allows users to quickly perform personalized literature searches (based on authorship and research interests) and then identify potential collaborators or competitors who have published in the same research areas. Unfortunately, while biomedexperts.com is a “monster” web-based, literature search application, the communication and interactivity between community members is extremely limited and almost non-existent.

Finally, for those of you who are tired of using PubMed’s arcane Boolean search algorithm to find relevant publications, you might consider trying a new free search engine (semanticmedline.com) that allows users to search MEDLINE using phrases or “conventional sentences." Cognition Technologies, creator of the site, says its “semantic natural language processing technology "incorporates word and phrase knowledge to comprehend the meaning and nuances of the English language." Although early reviews suggest that semanticmedline.com might not powerful enough for doing comprehensive science literature searches, it may be useful in situations when you are working on a time-sensitive project or you need to quickly find an article for this afternoon’s journal club meeting (that you failed  to enter into your blackberry or iPhone).

Check them out—they are all pretty cool (for scientists anyway-not that there is anything wrong with that)!

Until next time

Good Luck and Good Job Hunting!!!!!!!!

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The regulatory problems at Wyeth continue. The US Food and Drug Agency announced that it issued an approvable letter for Tygacil (Wyeth’s tetracycline-like antibiotic) to treat community acquired pneumonia (CAP). Apparently, FDA regulators want more data on the effectiveness and safety of Tygacil in severe cases of CAP and additional information on possible liver toxicity.

Tygacil, an intravenously administered antibiotic, won FDA approval in 2005 to treat adults with complicated intra-abdominal infections and complicated skin and skin-structure infections. Tygacil had about $138 million in sales last year; falling far short of the projected $500-$800 million in annual sales that it was expected to yield when it was first brought to market. If Wyeth gains approval for CAP, expect Tygacil sales to soar.

In other regulatory news, FDA granted Wyeth “fast-track approval” for a new version of its market-leading pediatric pneumococcal vaccine called Prevnar. The new 13-valent formulation will provide protection against 13 different pneumococcal serotypes. The older version only provided protection against 7 serotypes. Wyeth hopes to complete its filing for pediatric use of the new Prevnar vaccine in early 2009. Prevnar is Wyeth’s second-leading product with sales of about $2.5 billion in 2007.  

The new Prevnar vaccine will likely go head-to-head with GlaxoSmithKline’s new 10-valent pneumococcal vaccine  called Synflorix^Tm which is in late stage clinical development and is currently being reviewed for marketing approval in the EU. Unlike Wyeth’s vaccine, Synflorix^Tm  was found to be effective in protecting against otitis media (ear infections) caused by Haemophilus influenzae.

Until next time,

Good Luck and Good Job Hunting (avoid Collegeville, PA)!!!!!!!!

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