Trouble in the Blogosphere: The Brouhaha at ScienceBlogs

Because I was traveling for the past couple of weeks, I missed an article entitled “Unnatural Science” by Virginia Heffernan that originally appeared in the July 31 edition of the New York Times Magazine. After returning home this past Sunday, I had the opportunity to read it and what a read it was!

 It was an apt and brilliantly written piece about the often venomous and offensive blogging that has gone on for several years at ScienceBlogs: a science blogging collective overseen by the Seed Media Group. Interestingly, BioJobBlog was approached about a year ago by the Seed Media Group to consider blogging under the ScienceBlogs umbrella. For those of you who may not know, the bloggers who write for ScienceBlogs get paid based on the amount of site traffic that their blogs generate. While the sums of money that are paid are nominal, graduate students and postdocs, and even Assistant Professors can blog to their hearts content and make a couple of hundred dollars each month while waiting for the results from experiments that may be incubating. However, after reviewing the content and quality of some of the so-called blogs at ScienceBlogs, I respectfully declined Seed Media’s offer to come aboard.

Unbeknownst to me, a couple of months ago a group of 20 or more bloggers “angrily parted ways with ScienceBlogs because is started running Food Frontiers a nutrition blog that PepsiCo paid to have on the site” wrote Ms Heffernan. Also, she noted, “In farewell posts the bloggers charged that the advertorial was deceptive and undermined the purpose of the collective.” According to the article, Seed Media Group quickly removed the “tainted blog.” Unfortunately, the damage had been done and the action wasn’t sufficient to prevent other bloggers from leaving.

Unfortunately, my past experiences and “run ins” with several ScienceBlogs bloggers (“On Becoming a Domestic and Laboratory Goddess” and GrrlScientist, on Living the Scientific Life (Scientist, Interrupted) were extremely unpleasant, humiliating and unprofessional. After reading Ms Heffernan’s piece on the often caustic, offensive and inappropriate remarks made by many of the bloggers who write for ScienceBlogs I felt vindicated in my assessment of the quality and veracity of the writing at the collective. To that end, she wrote “And while I found interesting stuff here and there, I also discovered that ScienceBlogs has become preoccupied with trivia, name-calling and saber rattling. Maybe that’s why the ScienceBlogs ship started to sink.”

 While I think ScienceBlogs is a great idea and has merit, the people who run the site have failed to realize that they cannot allow scientists to say and publish whatever they want. Unfortunately, many of these well-educated and supposedly erudite scientists have inadequate social skills, over-sized egos and the notion that the freedom of speech gives them permission to say whatever they like no matter how offensive or odious it may be.

However, what I think is even more egregious than the offensive comments and slurs against people was the holier-than-thou attitude adopted by many of the bloggers who left Science Blogs because the Food Frontier Blog was sponsored by PepsiCo. After all, how could ScienceBlogs management allow a corporate entity to sponsor a blog and possibly denigrate and call into question the science discussed by other bloggers? To that end, I bet many of the defecting bloggers wouldn’t scoff at the opportunity to get research grant monies from a company interested in their research. In fact, it would be interesting to see how many of the bloggers at ScienceBlogs have research contracts and agreements with pharmaceutical, biotechnology and medical devices companies.

I actually feel bad for the Seed Media Group because the company is run by a bunch of good guys who are trying to do the right thing. That is, discussing and promoting science in the blogosphere with the hope of improving the public understanding of science and technology. Maybe it was time for the bloggers who left to go. There will be other bloggers to take their places. For the foreseeable future, BioJobBlog will remain independent.  However, if ScienceBlogs wants to make me an offer I can’t refuse; than I am all ears!

Until next time...

Good Luck and Good Blogging!!!!!!!!!

 

Biocareers: Some Advice for Would Be Entrepreneurs

More and more people are losing their corporate jobs because of the recession. The bleak job market coupled with diminishing opportunities for older, seasoned employees is forcing many to consider starting their own businesses to join the ranks of the self employed. However, before you take the leap, I highly recommend that you read Phyllis Korkki’s article in this Sunday’s New York Times entitled “Taking the Leap To Self Employment.

As a person who successfully made the leap, she offers amazing insights into what it really takes to be successful as an entrepreneur or small business owner. Most importantly, would be entrepreneurs must possess three important characteristics: motivation, drive and passion. If you lack any of the three, chances are that you are not cut out to be self employed or entrepreneurial enough to start your own company. Also, she aptly points out that one of the major drawbacks of self employment is loneliness. I cannot stress enough that this is the major complaint of most self employed persons that I know. 

While nobody wants to admit it, humans are social animals who need to interact with one another to fulfill the evolutionary need to be “social.” Luckily, the advent of social media has helped to overcome the daily loneliness experienced by many entrepreneurs and self employed persons. That said, before you make the leap, please read the article—it will help to determine whether or not self employment is right for you!

Until next time...

Good Luck and Good Job Hunting

 

Bucking the Trend: Regeneron Pharmaceuticals to Hire 500 New Employees

While attending the Advanced Learning Institute conference “Social Media and Pharma” earlier this week I happened to sit down next to Laura Lindsay, a member of Tarrytown, NY-based Regeneron Pharmaceuticals’ corporate communications team. Not surprisingly, we struck up a conversation and I learned that unlike most pharmaceutical and biotechnology companies Regeneron is looking to hire 500 new employee over the next year or so. Yes, you heard it correctly: 500 NEW EMPLOYEES. The company currently employs about 1,200 people.

Regeneron’s hiring spree is largely based on a lucrative research relationship with its partner Sanofi-Aventis and pending positive results from three Phase III clinical trials for several drugs that the company is developing to treat colon cancer, gout and macular degeneration. Industry analysts predict that approval of any or all of the three new drugs may allow Regeneron to Its products could eventually take on Roche Holding AG's $6 billion cancer drug, Avastin, and $3 billion Lucentis eye-disease medicine. The gout drug could attract annual sales of $500 million or more, analysts estimate.

Regeneron is currently not profitable and has one of the largest research budgets (in excess of $700 million) in the biotechnology industry. The 20 year old company sells only one product called Arcalyst; which was approved to treat rare genetic conditions such as Familial Cold Auto-inflammatory Syndrome (FCAS) or Muckle-Wells Syndrome (MWS). Arcalyst annually generates about $20 million in sales. Its current market capitalization is about $2.0 billion. Interestingly, I used to occasionally hang out with one of the company’s founders while I was a postdoc at Columbia Medical School.

While I don’t exactly know what types of jobs are available at Regeneron, you can easily find out for yourselves by visiting the company’s job search center. To learn more about Regeneron please click here.

If anybody out there knows of other life sciences companies that are hiring, please send me the information and I will post it!

Hat tip to Laura for the heads up!

Until next time...

Good Luck and Good Job Hunting (maybe things are really starting to turn around)!!!!!!!!!!!!



 

Managing Emotional Fallout After Losing a Job

Losing a job is a BIG deal whether you were layed off, fired or right-sized out of it. Not only do you have to worry about health insurance, bills and paying rent or making a mortgage payment, you must also deal with a myriad of self esteem and emotional issues that frequently arise after losing a job. While there are many articles and books that describe how to functionally conduct a job search after being layed off, there are only a handful that discuss how to cope with the stress and negative emotions that frequently accompany job loss.

Many people who lose their jobs frequently experience emotions like anger, desperation, hopelessness and even depression. These feelings must be acknowledged and then addressed and managed because they not particularly useful when looking for a new job. Further, when left unattended, these feelings can exact both a financial and an emotional toll on the unemployed.

In this Sunday’s New York Times, Phyllis Korkki, who writes “The Search” column describes how to manage the negative emotions and financial problems commonly associated with losing a job. She also provides tips on how to minimize “the pain” and accentuate the positive after experiencing a job loss.

Until next time...

Good Luck and Good Job Hunting!!!!

 SocialTwist Tell-a-Friend

Tired of the Swine Flu? Check Out the Coxsackie Virus

On several occasions while driving in upstate New York, I noticed an exit sign on the NY State Thruway for Coxsackie, NY. And, not surprisingly, I began to wonder whether or not the Coxsackie virus was named after this obscure upstate NY town.

I first learned about coxsackie viruses as a graduate student while taking a medical virology course at the University of Wisconsin taught by the late noble laureate Howard Temin. However, despite a thirty year friendship with Vincent Racaniello, a BioCrowd co-founder and virologist extraordinaire, I never asked him about the origin of the coxsackie virus name. Much to my surprise, he had recently taken a trip to upstate NY and noticed the Coxsackie NY exit sign while driving on the thruway. This prompted him to blog about the coxsackie virus isolation, its pathogenic properties and of course, the origin of its name!

Coxsackie NY and the virus named after it 

by Vincent Racaniello,PhD

Recently while driving north on the New York State Thruway I passed the exit for the town of Coxsackie, NY (population 8,884). I grabbed my camera and photographed the exit sign, and reminded myself to write about the virus named after this small town.

In the summer of 1947 there were several small outbreaks of poliomyelitis in upstate New York. Gilbert Dalldorf, the director of the Wadsworth Laboratory in Albany, NY, and his associate Grace M. Sickles investigated this outbreak. In particular they sought polioviruses that could replicate in mice. This search was motivated by the fact that research on poliovirus required the use of monkeys which were extremely expensive. Dalldorf had attended the Fourth International Congress for Microbiology in 1947 where he heard that very young mice – suckling mice – could readily be infected with Theiler’s virus.

Dalldorf and Sickles made fecal suspensions from two children suspected of having poliomyelitis, and inoculated these into adult and suckling mice. Only the suckling mice (1 – 7 days old) developed paralysis; animals more than one week old were resistant to infection. The damage responsible for limb paralysis was widespread lesions in skeletal muscles, not in the central nervous system as occurs with poliovirus. Further study revealed that the viruses could be distinguished serologically from poliovirus.

Not only had Dalldorf and Sickles identified the first members of a very large group of human viruses, but they also introduced and popularized a new and inexpensive animal into the virology laboratory – the suckling mouse. In 1949 Dalldorf suggested that the new viruses be called Coxsackie viruses, because the first recognized human cases were residents of that New York village. This unique name is of native North American origin.

Over ten years later the importance of this work was recognized by Dr. Max Finland of Boston City Hospital:

The isolation by Dalldorf and Sickles of viruses which produced paralysis with destructive lesions of muscle in sucking mice and hamsters, from the stools of two children with signs of paralytic poliomyelitis was an achievement that may rank in importance with Landsteiner and Popper’s production of human poliomyelitis in monkeys.

In subsequent years many different Coxsackie viruses were isolated that cause a variety of clinical syndromes. Today at least 30 serotypes of Coxsackie viruses are classified in the enterovirus genus of the Picornaviridae. The viruses are classified into groups A or B depending upon the pathological effect in suckling mice.

Not every locale is pleased to have a virus named after it. In May 1993, an outbreak of an unexplained pulmonary illness occurred in the southwestern United States, in an area shared by Arizona, New Mexico, Colorado and Utah called “The Four Corners.” Muerto Canyon was proposed as the name for the etiologic agent of the disease, because the virus was first isolated from a rodent near the canyon. However after residents objected, the name Sin nombre virus was given to the agent of hantavirus pulmonary syndrome.

Dalldorf G, & Sickles GM (1948). An Unidentified, Filtrable Agent Isolated From the Feces of Children With Paralysis. Science (New York, N.Y.), 108 (2794), 61-62 PMID: 17777513

 SocialTwist Tell-a-Friend

Jobseekers Beware!

We are living in financially uncertain times. While economic indicators suggest that the recession might be drawing to a close, most financial pundits agree that unemployment will continue to rise  long after the economy has improved. Most people who have lost a job will tell you how emotionally and psychologically—not to mention financially—debilitating it can be. People who have been unemployed for more than a couple of months are typically desperate to find work. And, as the old adage goes “Desperate times call for desperate measures.” To that end, many unemployed workers may consider job opportunities that they normally wouldn’t consider during more certain times. Unfortunately, criminals, grifters and con artists are keenly aware of this and frequently prey upon and take advantage of unemployed workers.

Over the past several months, I began receiving e-mails messages about “mystery shopper” and “logistic agents” job opportunities. At first, I thought that these so-called job opportunities looked interesting. However, after digging a little deeper and scrutinizing the ads more carefully, I realized that these were little more than artfully-designed scams. This, according to an article written by Riva Richmond in today’s New York Times, is only the “tip of the iceberg.” I highly recommend that you read the article to learn how to protect yourself and avoid being scammed while looking for new employment opportunities.

Until next time....

Good Luck and Good Job Hunting!!!!!!!!

 SocialTwist Tell-a-Friend

Methicillin Resistant Staphylococcus aureus: A Growing Link between MRSA Infections and Pigs

That methicillin resistant Staphylococcus aureus (MRSA) is in the news again is not surprising. However, to my knowledge, Nicholas Kristof‘s article in today’s New York Times may be the first Op-Ed piece written by a non-scientist about the growing threat and seriousness of MRSA infections. Mr. Kristof apparently became aware of MRSA when he was contacted by Tom Anderson, MD, a Camden, Indiana physician who was experiencing “phenomenal levels of MRSA infections" in his community.

Beginning in the early 1990s, Dr Anderson noticed a rapidly rising incidence in the number of community acquired skin infections caused by MRSA among his patients. Most of Dr Anderson’s patients were swine farmers—the predominant industry in Camden. At first puzzled by the growing incidences of MRSA outbreaks, Dr. Anderson began to suspect that his patient’s pigs may be the source of growing number of cases of MRSA skin infections. He was reluctant to alert public health officials about his suspicions because any hint livestock-related health issues might jeopardize the livelihood of many of his neighbors and friends. By last fall, however, Camden’s MRSA epidemic had grown so large that Dr. Anderson could no longer remain silent. Rather than alert the authorities himself, he decided to invite Mr. Kristof, an investigative reporter, to visit him in Camden and break the story. Unfortunately, before Mr. Kristof could visit, Dr. Anderson died abruptly at age 54. There was no autopsy, but a blood test suggested he may have died from a heart attack or aneurysm. And—this is where the story gets interesting—a recent Dutch study has linked porcine MRSA isolates to a case of human endocarditis. Dr. Anderson had himself suffered at least three bouts of MRSA infections.

In another Dutch study conducted in 2004, MRSA strain ST398 (which caused the endocarditis in the more recent study) was isolated from three family members, three farm workers and 8 of 10 pigs from a single farm. Since then, strain ST398 has spread rapidly through the Netherlands — especially in swine-producing areas— and pig farmers there are 760 times more likely than the general population to carry MRSA. More recently, a study conducted by public health officials in Ontario, Canada showed that 20% of pig farmers were colonized by strains of MRSA genetically identical to those isolated from European pigs. Finally, a 2008 study conducted in Iowa, reported that strain ST398 was isolated from 45 percent of pig farmers and 49 percent of hogs that were tested. Together, these studies suggest that colonization of swine by MRSA and pig farmers is very common and that swine (and possibly other agricultural animals) could become an important reservoir for strains of MRSA.

While not conclusive, most infectious diseases experts believe that the emergence of MRSA and antibiotic resistant bacteria can be directly linked to the widespread and rampant use of antibiotics as growth enhancers in livestock feed. Despite the alarming emergence of multiple antibiotic resistance bacteria, livestock producers in the US and elsewhere continue to add antibiotics to livestock feeds. This led Mr. Kristof to lament that “we as a nation have moved to a model of agriculture that produces cheap bacon but risks the health of all of us.” Not surprisingly, as is frequently the case, big business has chosen to place profits before the health and safety of society.

Until next time...

 

Good Luck and Good Reading (look for Mr. Kristof’s Sunday column on the emergence of antibiotic resistant "superbugs")

SocialTwist Tell-a-Friend