BioJob News: Novartis to Expand Research Operations in Cambridge, MA

Novartis announced today that it will open a new research facility and hire an additional 150 people by the end of 2009 for a Research Center of Excellence in Virology in Cambridge, MA. That will increase the number of people employed by the company in Cambridge to more than 1,800 workers. Researchers at the new center will study vaccines for HIV/AIDS influenza, cytomegalovirus (CMV) and respiratory syncitial virus (RSV). 

The vaccine business once avoided like the plague by most pharma companies, has been growing by leaps and bound over the past five years and is sizzling hot these days. According to analysts, vaccines generated about $16 billion dollars last year. For example, Merck’s anti-human papilloma virus vaccine Gardasil generated $1.5 billion in sales in 2007.

Novartis clearly sees an upside in the vaccine business and is willing to make a wise investment for the future.

Until next time….

Good Luck and Good Job Hunting!!!!!

Social Networking and Scientific Research

Over the past year or so, social networking has taken the Internet by storm. This is largely  because social networking software purveyors like CrowdVine and Ning have provided out-of-the-box solutions that allow people to easily create social networks that strike their fancy. That said, will the advent of social networks do anything more than allow musicians to sell records or provide an easy place for people to hook up? To that end, Jessica a regular BioJobBlog reader sent me a story (see below) about a survey that was performed to gauge the possible impact of social networking on scientific research.

Social Applications to Play Deeper Role in Future Research

The future of social media will not just build friendships but support groundbreaking scientific discoveries.

Scientists and researchers are using social media… but mostly for professional reasons. A recent survey from 2collab reveals that over half of science, medical and technical information specialists working in academia and government institutions believe social networking will play a key role in shaping the future of research. Additionally, the study suggests tomorrow’s university faculty (respondents aged 25 - 44 in academic research positions who have published 1-10 articles) are already heavily using social media and are eager for the applications to be further developed for use in their work.

According to the survey which included 1,800 respondents, the top areas where social applications will have a major influence on research in the next five years include:

1.      Professional networking and collaboration (34.4%)

2.      Career development (26.4%)

3.      Critical analysis and evaluation of research data (25.3%)

4.      Dissemination of research output (24.5%)

5.      Conducting primary research (23.4%)

6.      Grant application and funding (22.7%)

Much to my delight, the results from the survey confirmed my belief that social networking among scientists would stimulate and be a boon to scientific research. This strengthened my conviction to move forward with the bioscience networking site, BioCrowd, that Vincent Racaniello and I plan to launch by the end of September, 2008. Rumor has it that their may be gifts for the first 100 people who join after launch.

So, don’t wait and become part of the BioCrowd today.

Until next time….

Good Luck and Good Social Networking (it will help you get a job!)

A Conundrum: The Importance of Stupidity in Scientific Research

 I previously wrote a piece which suggested that being perceived as smart is typically what separates the great scientists from the mediocre ones. To that end, whenever a former postdoctoral mentor (who I think is really smart) wanted to “motivate me” he would invariably say “C’mon Cliff, you’re a smart guy…..” Of course, the implication was that I wasn’t being smart enough or —as I heard it — “if you want to be as smart as me you better think harder and better”. According to a post by Karen Ventii at the Science to Life Blog, I wasn’t the only fledging scientist who was treated this way.

Does making a graduate student or postdoctoral fellow feel stupid motivate or hurt them? To learn more, read this provocative article by Martin Schwartz, PhD a professor at the University of Virginia that appeared in the April 28, 2008 issue of the Journal of Cell Science.

Until next time...

Good Luck and Good Job Hunting!!!!!!!

In Case You Were Wondering....Federal Research Funding for the Life Sciences Will Remain Flat

For the past 60 years, American science was second to none. However, the US is perilously close to losing that distinction. Put simply, American science, like its economy, is in free fall.

Federal funding, primarily through the National Institutes of Health (NIH), is the lifeblood of American life sciences research. Between 1998 and 2003, the federal government doubled NIH’s budget every year—almost 25% of all grant applications were funded and life was good! However, since 2003, budget increases have vanished and the NIH remains trapped in a five year run of flat funding. Research funding rates have fallen to 10% or less and many academic scientists are voluntarily leaving or being forced out of their jobs.

This is not the first time that funding levels have plummeted. From 1989 to about 1994 (when I was a tenure track Assistant Professor), funding rates fell from about 20% to less than 10%. However, back then, there was little global research competition and American was able to recover to retain its scientific dominance. However, the world is a very different place now and the supremacy of American science, particularly in the life sciences, is clearly at risk.

According to an article in the Trenton Times, (my local paper), science and engineering have accounted for close to half of the growth in the American economy since World War II. Analysts suggest that without adequate research funding and ready access to research grants fewer scientists will enter the profession. “Already Asian countries are graduating 10 times the number of scientists and engineers as the United States. If the current trends continue in about a decade 90% of the world’s scientists and engineers will be in Asia” According to Elias Zerhouni, current director of NIH “In 10 to 15 years we’ll have scientists older than 65 than those younger than 35. This is not a sustainable trend in biomedical research.” Unless federal funding for research is increased this ominous trend will continue. That said, it may be too little too late. As you all know, finding science jobs in the US these days is becoming increasingly difficult even for qualified applicants. With this in mind, one of the most well attended talks that I give at career development symposia is entitled “The Road Less Traveled: Alternate Career Paths for Life Scientists”. As much as I hate to admit it, traditional career pathways for most life scientists may be things of the past.

Clearly, something must be done to fix the problem in order to maintain the quality of American science. The easy fix, which has been used ad nauseam for the pasts two decades, is to increase short term federal research spending. However, history indicates that this approach fosters the boom and bust cycles that have continually plagued American academic science. Although the boom and bust approach is quintessentially American, I don’t think that it will enable American science to sustain its scientific dominance in today’s increasingly competitive world.

The number of young people interested in or entering science continues to plummet in the US. Ironically, the quality and access to American science education has never been better! So, why the disconnect? It’s simple—science jobs are scare, the pay is not great and life as an academician has become almost unsustainable. In my opinion, something has to change very soon or America will almost certainly lose its status as the preeminent purveyor of science in the world.

Until next time,

Good Luck and Good Job Hunting!!!!

GlaxoSmithKline Cuts More Jobs

The Avandia debacle is still ravaging the employee ranks at GlaxoSmithKline especially at its Research Triangle Park, North Carolina and in Philadelphia locations. According to a post at Pharmalot, the UK-based drug manufacturer is cutting as many as 350 jobs (2.0% of its workforce) at both locations. This represents an almost 40% reduction in drug discovery and development activities that take place at both sites.

These cuts come after GSK closed a factory and drastically cut its sales force late last year. To make matters worse (particularly for those folks who lost their jobs) GSK purchased an early-stage drug discovery company called Sirtris Pharmaceuticals for about $720 million earlier this year. Clearly, company executives have more faith in external rather than internal drug discovery at GSK.

The saga continues……

Until next time

Good Luck and Good Job Hunting (forget North Carolina)!!!!!

Genzyme Expands Its Irish Operations

Genzyme Corp announced yesterday that it plans to expand it research and manufacturing facilities in Waterford, Ireland. Genzyme originally set up the facility in 2001 and plans to add another 170 employees, expanding its Irish workforce to 600.

This is second time in less than a year that Waterford (internationally known for its crystal manufacturing) has received an investment from a foreign drug manufacturer. Israeli generic drug manufacturer TEVA made a $100 million dollar to expand its Waterford operations and boost its Irish workforce from 650 to 815.

The Irish government said it was offering assistance to subsidize the $200 million Genzyme expansion at the Waterford site. The amount and terms of the subsidiary were confidential and not disclosed. At present, drug companies with operations in Ireland  employ 25, 000 people.

Genzyme, with expertise in developing drugs to treat rare disorders, kidney disease and cancer, employs more than 10,000 people worldwide.

This is more good news for Ireland!

Until next time….

Good Luck and Good Job Hunting (in Ireland)!!!!!!!