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Have you ever found yourself in a situation where you needed important biological, genetic or other life sciences information quickly? Sure, you can Google the topic but it takes time to wade through all of the search results until you find the right one!

Carol Brown from Onlineuniversities.com sent me a list of the “100 Best Reference Sites for Science Students.” The list contains information for chemistry, environmental science and even geology.  I extracted the life sciences websites from the list and posted them below.  

1. Biology Online: On this site you can post questions in a forum, look things up in a bio dictionary, and read all kinds of informative articles and tutorials.
2. Everything Bio: Check out this resource to find a glossary, textbooks, images and a range of other online biology tools.
3. Life Science Dictionary: Try out this dictionary to look up life science terms and identify their meanings.
4. Molecular Biology Glossary: Students of molecular biology will appreciate this valuable research tool.
5. National Biological Information Infrastructure: Want to know and read about the research being done in the life sciences? Check out this site.
6. Biology Reference: You can look up loads of helpful biology terms in this online encyclopedia.
7. Biology Nation: From finding the best biology grad programs for looking up biology terminology, this site is a one-stop resource.
8. Dictionary of Cell and Molecular Biology: Search through this online dictionary to refresh your memory on the parts of the cell.
9. BioScience: With a dictionary, encyclopedia, links, software, and custom search tools, you’ll find more reference material than you could ever need on this site.
10. All Experts: Biology: Have a biology question you just can’t seem to find the 
11. Amino Acids Repository: Use this site as a reference on amino acid properties alone and in proteins.
12. Table of Standard Genetic Code: This site is a great reference when trying to remember which part of DNA goes where.
13. Talking Glossary of Genetic Terms: Don’t know how to say a particular term? No worries, this glossary will tell you and more.
14. Human Genome Acronym List: Don’t have a clue what the ASHG is? This site can help you look it up.
15. Genetics Resources on the Web: Search through this site for the best genetics resources the web has to offer.
16. National Human Genome Research Institute: This site offers a number of helpful educational resources for students young and old.
17. Genetics Virtual Library: Search by organism or topic to find the genetic information you need to do your homework.
18. Genetics Home Reference: Those studying genetic disorders will appreciate this quick online reference for conditions.
19. GeneTests: Even if you’re not in medicine, you’ll be able to find interesting and compelling information on this site.
20. Gene Cards: You’ll find a collection of concise information on just about every gene out there on this site.

While I can’t vouch for the quality of the  list, it looks to be pretty informative.

Until next time...

Good Luck and Good Studying!!!!!!

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While this isn’t a new topic, I wanted to raise the question again because I recently received a message  from a reader that greatly troubled me. The person who posted the comment has a PhD degree in biomedical engineering and is extremely angry with the existing system because of the lack of employment opportunities in her field. Put simply, she is so frustrated with the system that she no longer believes that it is ethical to advise young people to pursue careers in the life sciences. I know that she isn’t alone and that many of you share her anger and frustration with the lies (as she put it) about employment opportunities for life sciences PhD candidates and postdoctoral fellows

From time to time, I am invited by graduate students and postdoctoral fellows to talk about alternative careers in the life sciences. I try to remain upbeat and positive during my presentation but generally I can’t control myself by the Q&A session. Invariably, I rant and rave about how dysfunctional academia has become. Interestingly, I recently was uninvited by my former graduate department where I was slated to present a seminar on alternate career choices for life scientists. As the tenured faculty member (you know how I feel about tenure) who would have sponsored my visit told me “the seminars that we offer our students are scientific in nature and much different than many of the topics that I discuss on my very interesting blog.” Consequently, he informed me that I was no longer invited to give my talk (I was previously invited by the Department Chair who happened to be a former colleague of mine who decided to move to another institution before my visit). In an e-mail response to his un-invitation, I told him that I wanted to visit the Department and give the talk because I believe that my graduate education is what enabled me to maneuver the minefield that ultimately became my career path. Also, I told him that I wanted to share my insights and career experiences with current graduate students and postdoctoral fellows because I thought that many may benefit from them. Not surprisingly, I never heard back from him. 

The point that I am trying to make is that my message about alternative careers for PhD students is diametrically opposed to the mission of most PhD programs; which is to prepare 100% of their students for academic careers. Unfortunately, as I have stated many times in the past, only about 10% of those who receive life sciences PhD degrees land academic appointments. What are the remaining 90% of the folks who toiled long and hard for their PhD degrees suppose to do with their lives? In the past, as many as 50% or more of these students were able to garner jobs as research scientists at biotechnology and pharmaceutical companies or with government agencies like the CDC, FDA, EPA and others. Unfortunately, the pharmaceutical industry has laid off over 200,000 employees in the past 3 years, funding for biotech companies has hit an all time low and we are experiencing the worst recession in almost 70 years which is causing government agencies to stop hiring! This begs the question: what are graduate students pursuing PhD degrees and postdoctoral fellows suppose to do to put food on the table to feed their families and themselves? 

While I don’t have an easy answer to that question, I can tell you that getting angry and frustrated or dropping out of the system isn’t going to change anything. I will also tell you that the system isn’t going to change by itself! To that end, it may make sense for all of you angry and frustrated graduate students and postdoctoral fellows to band together and tell your advisors and mentors that “you are mad as hell and not going to take it anymore.” To show them that you are serious, I highly recommend that your offer them a plan to address your concerns about finding gainful employment (not decade long postdoctoral fellowships) following completion of your PhD degrees. For example, you may suggest that they add alternate career certificate and degree programs to their existing curricula. Or, if new programs are too costly, suggest that they offer courses that showcase alternate career options like entrepreneurship, science writing or medical communications. Finally, at the very list, insist that they work with local companies and organization to create sponsored internship opportunities and get them to commit to supporting annual career development symposia or job fairs for graduate students and postdocs.

For the past decade or more, I have struggled to convince many of my academic colleagues to consider any and all of the above suggestions. Unfortunately, my pleas for creation of new courses and programs have fallen upon deaf ears! Given my current lack of success, I suspect that it is going to take more than one person (me) to induce the academic establishment to consider systemic change. That said anybody who may be interested in joining the “cause” to improve employment opportunities for PhD life scientists, please feel free to contact me!

Until next time...

Good Luck and Good Organizing!!!!!

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Amber Johnson of Accredited College Online thought that BioJobBlog readers might be interested in an article that she authored entitled “10 Big Ways that the Recession is Hitting Higher Ed.”  It is an informative piece that might be of interest to high school and undergraduate students and parents who have kids in college.

10 Big Ways the Recession is Hitting Higher Ed

From elementary to college, schools around the nation have felt the recession in many different ways. As the economy sinks, the educational demands rise. Teachers are holding on to dear life for their jobs, students are struggling to pay for college and the states are running out of school funding. But even with all of these economic woes, there are still people eager to teach and happy to learn.

1. Budget Cuts. Since the beginning of the fiscal year, the U.S. has suffered a 5 percent drop (about $4 billion) from the amount of money state governments apportioned for higher education, according to a U.S. News & World Report article. This is directly affecting universities across the country, who’ve seen larger class sizes, less professors and counselors, as well as canceled courses, which experts say could "threaten the quality of education."
2. Spike in Tuition. College tuition has been an inevitable hurdle for many students and families for years, but in this recession, it stings that much more. Since 1982, college tuition and fees have increased 439 percent, which is about three times higher than the increase in family incomes, according to an ABC news report. In some cases, tuition increases are the school’s response to more financial aid requests, but these scholarships may not be enough to cover soaring prices.
3. Decline in Aid. Many states are cutting college financial aid programs when students need it most. An increase in unemployment and financial losses has caused 620,000 more students to apply for federal aid in the first quarter compared to last year. An Associated Press article reports that without financial assistance, students may be forced to drop out, transfer or be laden with debt.
4. Decline in Endowments. A major factor in these educational downturns is the decline in college endowments. Big and small donors simply aren’t giving back right now, which has caused hiring freezes, cutbacks on financial aid and halted construction projects, according to a Wall Street Journal article.
5. Graduate in Three Years.Graduating in three years is a surefire way to slash college costs. American colleges are now starting to offer three-year college degrees, which is the normal time frame for many British and Canadian students. It’s an upcoming trend, according to CBS MoneyWatch, that could make "elite education" more affordable.
6. More Kids Are Going Public. According to a CBS News report, private school enrollments have declined as many students make the switch from private to public schools. While some continue to pay top dollar for private school tuition payments, others have had to transfer to less prestigious schools to save money.
7. Arts Programs Suffer. With devastating budget cuts on the agenda, college art departments are the first area to be altered. According to a New York Times article, students can expect to see fewer teachers, programs and courses in the arts when they return to campus in the fall. While some colleges are phasing out programs altogether, others, like Louisiana State University, are holding off on new computers, production technology and traveling for conferences to lessen their demand for funding.
8. Growth and Decline of Majors. For college students, choosing the right major during the recession may secure a stable career in the future. Certain industries, such as journalism, entertainment and finance should be avoided, according to a report by College Finance 101, because they have seen the most turmoil during the recession.
9. Higher Community College Enrollment. With the recession at its peak, many college students have opted for the more affordable institutions — community colleges, according to The Chronicle of Higher Education. However, this influx of students has caused some community colleges to turn them away, claiming there’s not enough room, teachers and accommodations at these campuses.
10. Distance Learning is More Desirable. A big thing hitting the economy is online education. Whether people have lost a job, are fearful of losing one or want a degree, online colleges have open seats. A CNN report, titled "Riding out the recession in a virtual classroom," touches on the idea of investing in education during troubled times to have a back-up plan and find the right career path for you.

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People frequently ask me why I decided to get a PhD degree to become a scientist. For the past 30 years, I have tried to explain to people why I decided to spend seven long years of “blood, sweat and tears” to attain that elusive degree. While anyone who has earned a PhD degree understands what drove them to do it, it is difficult to explain to others that the decision has little to do with career paths and salary considerations and is largely driven by passion— and perhaps more aptly—obsession. That is why Carole and Richard Rifkin’s film “Naturally Obsessed: The Making of Scientist”—an emotional and gritty film that follows the lives of three Columbia graduate students on their quest to obtaining their PhD degrees—is resonating with scientists, students and the public.

The film, which took five years to make and was launched in March 2009, follows the progress of three X-ray crystallography graduate students, Rob, Killington (Kil) and Gabrielle, who worked in Larry Shapiro’s laboratory at Columbia University Medical Center. Work in Larry’s laboratory focuses on elucidating the X-crystallographic structure of proteins that are thought to be involved in appetite control. While Rob, Kil and Gabrielle share a common goal—getting a PhD degree—they are very different people. Rob is a rebellious, boisterous, self-assured free thinker (who was thrown out of a previous laboratory) whereas Kil is a more staid, soft spoken pragmatist from the Midwest. Gabrielle, who returned to graduate school to pursue a PhD degree after a stint as a laboratory technician at a company, loves science but isn’t certain that she has the mettle to realize her dream. Each of them understands that time is of the essence and they work feverishly and unrelentingly  to insure that their competitors don't beat them to the punch and publish first!

Despite their obvious personality differences, each is driven and obsessed with producing perfectly-formed protein crystals that are suitable for X-ray crystallography analysis. The film accurately and painstakingly depicts the inevitable emotional “ups and downs” of laboratory research, the personal struggles and the often difficult life decisions that are made when pursuing a PhD degree. In the end, Rob, Kil and Laura find their own career paths as scientists and perhaps, more importantly. come to terms with the decisions that they made during their journeys.

Carole, a documentary filmmaker, and Richard, Chairman Emeritus of the Sloan-Kettering Institute and founding Chairman of the New York Structural Biology Center, made the film to portray the “reality of doing science” and raise awareness about scientific research. The film emphasizes that science, like art, requires creativity, persistence and unyielding commitment and dedication. The Rifkinds interviewed many NYC-based academic laboratories before choosing Larry Shapiro’s laboratory as the subject of their documentary film. Larry’s laboratory was chosen because X-crystallography is visual (and lends itself to film making) and Carol had a hunch that “there was a story to be told there.”

During a recent interview with the Rifkinds, I mentioned that if I had seen the film as a high school or undergraduate student, I probably would have skipped graduate school. Carole responded and said, “Yes, the hard work and emotional challenges portrayed in the film might turn some students off but we wanted to portray scientific research the way it is and remain true to its realities.” She added, "while the film focuses on science graduate students it is also relevant and accurately reflects the trials and tribulations experienced by PhD students in the humanities and the arts.” 

One of the more troubling moments of the film for me is when Larry mentions that scientists, like artists, “represent the fringe of society.” The fact that a prominent, successful scientist views himself as different, and on the fringes of society, doesn’t bode well for the public perception of science or scientists for that matter. Another troubling aspect of the film is that Rob, Kil and Gabrielle are clearly being groomed for academic careers despite the fact that roughly only 10% of life sciences PhDs secure academic positions at the end of their training. I pointed this out to Richard and he said that he agrees that it is a troubling trend and that “alternate career options for PhDs is the subject of Carole's  and his next film.”

Since it launch in March, the film has been screened at over 60 high schools, colleges, medical schools, professional science associations, government agencies and biotechnology companies. While the film may not be “right” for everyone, it is a must see for graduate students and postdoctoral fellows and for members of the public who want a rare glimpse into the emotionally-charged and highly competitive world of scientific research. For those of you, who may be interested in arranging a screening, please visit the Naturally Obsessed: The Making of a Scientist website or contact Hayley

Until next time....

Good Luck and Good Job Hunting!!!!

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After yesterday's post about career planning for life scientists, one of my soon to be former students in the Fundamentals of Bioscience Program aptly pointed out that my readers might have benefitted more if I had, in fact, offered information about alternate career possibilities for bioscientists.  I don't want the student to get too overconfident but I had the same thought immediately after I uploaded the post.  

Rather than modify the previous post, I decided to upload the presentation that I gave to the U Penn Graduate Student Biomedical Association yesterday.  However, as many of my former (or soon to be former) students will tell you, my PowerPoint presentations, while informative, are not as complete as you might think.  To get the real skinny on alternate careers, you will have to attend one of my seminars on the topic where I provide attendees with additional pearls of wisdom and some funny stories about my own journey along an oft times circuitous career path!

Until next time.....

Good Luck and Good Job Hunting

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Unlike others, life scientists have been slow to use social media to look for jobs or network to enhance career opportunities.  Many scientists  have  Facebook accounts but view it and other social media tools like Twitter simply as a means to stay in touch with family and friends.  However, social media can be a very powerful tool for scientists who are looking for jobs or the next big career move.

To that end, I presented a seminar at Experimental Biology this past weekend in New Orleans entitled "Social Media and Career Development for Life Sciences" that offer suggestions on how to use social media to land a job or jumpstart a career in the life sciences industry.  For those of you who may be interested, I posted the presentation below:

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Did you know that the top ten pharmaceutical companies in the world spent close to $50 billion dollars last year on R&D? That sum could be used to purchase the entire US biotechnology industry except for the five largest companies—Genentech, Amgen, Gilead Genzyme and Celgene. Further, pharma’s R&D budget is about 4 times the R&D budget of all of the US biotechnology companies combined. According to a blurb in breakingviews.com, Pfizer alone spent $8 billion last year which was greater than the sum spent by biotech’s top five companies. What this tells us is that pharmaceutical companies are grossly unproductive when it comes to drug discovery and development. This would explain why nearly three-quarters of all new medicines approved for sale in the US last year originated at biotechnology companies.

It is becoming increasingly apparent that biotechnology companies are much more efficient at R&D than pharmaceutical companies. More importantly this suggests that something must change so that pharma can continue receive adequate ROI on internal discovery programs. Perhaps big pharma ought to spend a greater portion of its R&D budget on biotech mergers and acquisitions rather than continuing to invest in inefficient and failing internal R&D programs. While biotechnologynology companies are exceptional in drug discovery, they are severely lacking when it comes to clinical development of new drugs. This is largely due the high costs of conducting human clinical trials (which are required for regulatory approval of all new medicines). Most biotechnology companies are strapped for cash and don’t have sufficient funds to conduct clinical trials on their own.

Not surprisingly, given the recent financial downturn, there has been a recent spate of deals in which pharma has been willing to pay large sums of money for clinical development rights to promising new biotechnology drugs. Moreover, a majority of the almost 160,000 employees layed off by pharma companies in the past few years have been R&D scientists. This suggests that pharma is beginning to realize that its money may be better spent doing deals or buying biotech companies rather than continuing to invest large sums of money into it’s own unproductive R&D programs. Unfortunately, this paradigm shift doesn’t bode well for doctoral students and post-doctoral fellows who are training in the life sciences. This is because many entry-level biotech positions, traditionally filled by newly-minted PhDs and postdoctoral fellows will likely be filled by experienced, pharmaceutical employees who lost their jobs in the recent rounds of layoffs. As much as I hate to say this, if I were a life sciences graduate student or postdoctoral fellow considering an R&D career in industry, I would begin to explore alternative career options.

Until next time….

Good Luck and Good Job Hunting!!!!!!!

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For the past five years, I have been giving career development seminars that offer graduate students and postdoctoral fellows alternate careers choices (instead of research) for life scientists. The intent of these seminars is to get students who may not be enamored with a possible life long career at the bench (I know that there a lot of you out there) to think about what they really want to do after they complete their graduate or postdoctoral training.

I recently met Jane Chin (on Twitter) who, like me, has had an unorthodox career trajectory for a life scientist. After exchanging several tweets, I learned that we both are microbiologists, Cornell University graduates, entrepreneurs and social media enthusiasts. But, the main reason I am telling you about Jane is that she crafted a fascinating PowerPoint presentation entitled “3 Lessons About Career Life From a Career Nomad” that provides insights into the decisions and choices that she made to shape her current career path. I highly recommend that you take a peek at the presentation—it may help to reduce some future career stress and angst!

Until next time…

Good Luck and Good Job Hunting!!!!!!

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I just returned from the Annual Biomedical Research Conference for Minority Students (ABRCMS) that was held in Orlando from November 5-8, 2008. The annual meeting, which is configured like most life sciences conferences with plenary oral sessions and poster presentations, is primarily intended to expose minority students to possible career opportunities in the life and biomedical sciences. I was at the meeting working for FASEB Careers as a career development and resume critiquing consultant.  

I have to say that this year's  ABRCMS was one of the most exciting and motivational meetings that I have attended in my career as a scientist and educator. Part of  the excitement and upbeat feeling at the meeting may have been a direct  result of last Tuesday's historic election of Barack Obama (who wasn't excited?).  Nevertheless, I met countless numbers of bright,  highly motivated and talented minority students who want to pursue careers in science, medicine and sometimes both! I was pleasantly surprised to learn that many of the undergraduate students who attend this meeting are actively engaged in basic research in laboratories at their institutions. Further, unlike many of their non-minority counterparts, most of the students who I chatted with were well informed about their intended careers and had divined well thought out strategies to help them realize their career goals and aspirations.

Kudos to the conference organizers and their sponsors! I look forward to attending next year’s conference in Phoenix, AZ.

Until next time…

Good Luck and Good Job Hunting!!!!!

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