Promoting Science Literacy Among Undergraduate Humanities Students One Student At A Time

In 2005, The National Academy of Sciences issued a worrisome report entitled “Rising above the Gathering Storm: Energizing and Employing America for a Brighter Economic Future” that warned that America is slipping in competitiveness in all areas of science.

While this ought to have been a wake-up call for all Americans, in 2010, the Academy issued an update entitled “Rising above the Gathering Storm: Approaching Category 5." Not surprisingly, the findings in the update indicate that the US is still lagging in its capacity to innovate and compete and that the trend continues to move in a downward direction. For example, in 2006 (the most recent year for which data are available) 16 percent of American college students received undergraduate degrees in natural sciences or engineering as compared with 47 percent in China, 38 percent in Korea and 27 percent in France. Recommendations in the original report called for creation of 25, 000 undergraduate scholarships per year in math, science and engineering. Although the updated report indicated that Congress had taken some steps to implement the recommendation, progress has been severely lacking in this area.

Almost all US colleges and universities require that undergraduate students have some instruction in science. Unfortunately, most of these courses are lecture driven and lack a laboratory component (mainly because laboratory instruction is costly and time intensive). This is problematic because science is a laboratory driven discipline that requires data collection and analysis; neither of which is taught in most lecture settings. Recognizing the growing lack of science literacy among American undergraduate students, Leon Botstein—music director and conductor of the American Symphony Orchestra and President of Bard College an artsy liberal arts college in NY—decided to do something about it. To that end, he created a program at Bard called Citizen Science; a mandatory science course conducted during winter break that all Bard freshmen are required to take for graduation.

Citizen Science is a two and a half week long program in which students spend six hours per day immersed in laboratory science. The 2011 program taken by 480 students focused on the molecular biology of infectious diseases. Using laboratory equipment, computer modeling and classroom discussions, student explored various aspects of infectious disease research including bacterial and viral detection, creation of vaccines and techniques that can be used to manage global disease outbreaks. The students were taught by two dozen scientists who were recruited from all over the country. There are no grades or credits received by program participants. This was done to promote learning for learning sake according to Brooke Jude an assistant professor of biology and the director of Citizen Science.

Botstein, who incidentally is the brother of David Botstein a world renowned geneticist at Princeton University, has been an outspoken critic about deficiencies in American education. He previously has taken many of his colleagues to task for “shirking their responsibility to create a well-rounded citizenry.” Botstein, with help from his brother, decided to “put his money where is mouth is” by creating Citizen Science. 

According to Botstein, “The most terrifying problem in American university education is the profound lack of scientific literacy for the people we give diplomas to who are not scientists or engineers.” He added, “The hidden Achilles’ heel is that while we’ve found ways to educate scientists in the humanities, the reverse has never really happened. Everybody knows this, but nobody wants to do anything about it.”

Not surprisingly, the Citizen Science Program has received mixed reviews from the 480 Bard freshmen who participated in the inaugural program. After all, a majority of the students who chose to attend Bard have a decided bent toward music and the arts, not science. Nevertheless, many students suggested that their two and half week scientific sojourn has taught them to think more critically about science. Next year’s theme for the Citizen Science program may be energy or climate change.

While Bard’s Citizen Science program is a fantastic idea, not all colleges or universities have the financial largess or scientific connections necessary to create similar programs at their institutions. Perhaps Congress ought to establish funding mechanisms (in addition to the 25,000 math and science scholarships each year) for post secondary institutions interested in replicating the Bard program.

Government officials can no longer deny what the data are showing them; science literacy in the US is plummeting and we are REALLY at risk of losing our competitive and innovative edges in math, engineering and science. Put simply, it is no longer a question of “if” but “when.”

Until next time....

Good Luck and Good Job Hunting!!!!!!

 

Pfizer to Purchase King Pharmaceuticals

Pfizer today announced that it will purchase Bristol, TN-based King Pharmaceuticals for $3.6 billion in cash or $14.25 per share: an approximately 40% premium over King’s closing share price yesterday.

King is a diversified specialty pharmaceutical drug delivery and clinical development company with expertise in delivery of easy to abuse or misuse pain medicines, self injecting delivery devices and animal health

The acquisition will help Pfizer push forward with its new emphasis on biopharmaceuticals and rare disease drugs; both currently require parenteral administration to patients.

The King acquisition is consistent with Pfizer’s M&A strategy to enter new therapeutic areas and markets. In the last 10 years or so Pfizer has acquired Warner Lambert, Pharmacia, Wyeth and several smaller companies including Sugen, Copely Pharmaceuticals, Encysive Pharmaceuticals, Serenex and others.

Whether or not Pfizer can successfully integrate King’s expertise and business units into its existing monolithic corporate structure remains to be see. Pfizer is still trying to right itself after it acquired Wyeth Pharmaceuticals for $65 billion early last year.

Big pharma companies—flush with cash—have been on a buying spree of late. Unfortunately, the availability of this cash is directly related to the massive downsizing and layoffs that have taken place in the industry over the past few years. That said, if I were a King employee, I would be dusting off my resume!

Until next time

Good Luck and Good Job Hunting

 

What Do a New Award Winning Book and BioCrowd Have in Common?

Vincent Racaniello, virologist extraordinaire and a BioCrowd co-founder is slated to appear on ABC World News this evening to discuss Rebecca Sloot’s new book entitled The Immortal Life of Henrietta Lacks. The book details the life of little-known Henrietta Lack whose cancerous cervical cells (subsequently called HeLa cells by the scientists who managed to cultivate and immortalize them in the laboratory), revolutionized the field of virology and changed the way viral vaccines are manufactured.

Rebecca Skloot, the author, is an award-winning science writer, and a contributing editor at Popular Science magazine; she's worked as a correspondent for the NPR show RadioLab, and PBS Nova ScienceNOW. Her writing appears in The New York Times Magazine, O: The Oprah Magazine, Discover and others. The “Immortal Life of Henrietta Lack” is her first book.

So, why is Vincent being featured on tonight’s newscast about the HeLa book? For those of you who don’t know, Vincent has spent almost 30 years unraveling the molecular mechanisms by which the polio virus causes disease. And, as many of you may know, HeLa cells are the cell line of choice to cultivate polio virus in the laboratory. In addition to cloning the polio virus receptor in HeLa cells, members of Vincent’s laboratory have elucidated the genes and their proteins responsible for the neurotrophic effects of the virus that can lead to paralysis from polio infections. Further, for those of you who may not know, Vincent, while a postdoctoral fellow in David Baltimore's laboratory, was the first to demonstrate that transfection of HeLa cells with cDNA made from polio virus genomic RNA (using the newly discovered HIV reverse transcriptase enzyme that resulted in Baltimore winning the 1975 Nobel Prize in Physiology or Medicine) yielded infectious polio virions.

While Vincent’s findings greatly aided research to elucidate the underlying pathogenic mechanisms of the polio virus, it transformed and revolutionized the entire field of RNA virology. Prior to Vincent’s discovery, it was impossible to study the molecular biology of RNA viruses using recombinant methods because unlike DNA, there are no known RNA restriction enzymes. The ability to transcribe viral RNA into cDNA molecules that yield infection RNA viral particles permitted researchers to dissect RNA virus genomes (using recombinant DNA technology) to determine contribution of individual genes to viral pathogenesis.

Vincent, one of only a handful of virus pioneers, is now applying his considerable pioneering talents to social media because he believes that Web 2.0 tools like blogs, podcasts, videos and social networking sites can be successfully used for science education and improving the public understanding of the life sciences.

Until next time...

Good Luck and Good Viewing (ABC World News Tonight)!!!!!!

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Pfizer Gets Out in Front of Healthcare Reform

Pfizer, the world’s largest drug maker, announced on Thursday that it is unveiling a new program that will let people who have lost their jobs and health insurance to keep taking Pfizer medications — for free, and for up to a year. The company will provide more than 70 of its prescription drugs ranging from Viagra to Lipitor at no costs to unemployed and uninsured Americans who lost their jobs since Jan. 1 and have been taking Pfizer drugs for me than three months. It is not clear how much Pfizer will spend on the program and whether or not costs will be capped.

The announcement comes amid massive job losses caused by the recession and a campaign in Washington to rein in health care costs and extend coverage. The move could earn Pfizer some goodwill in that debate after long being a target of critics of drug industry prices and sales practices. The program also likely will help keep those patients loyal to Pfizer brands. Don't be surprised if other pharmaceutical companies announce similar program over the next few weeks.

Pfizer and the rest of the drug industry wants is trying to have a voice in the debate over how to overhaul the U.S. health care system, partly by joining in a pledge this week to help hold down inflation of health costs. In the mean time, drug companies have been raising prices on their drugs, partly to offset declines in revenue as the global recession reduces the number of prescriptions people can afford to fill.

Pfizer ought to be commended on the program and its concern for the health and well being of unemployed and uninsured Americans. However, it is important to point out that this is little more than a high profile, marketing campaign designed to improve the image of drug makers. More important, it is the first public acknowledgement that drug makers are willing to engage legislators in discussions about how to reform healthcare to reduce costs and cut expenditures. 

What really is at stake here is whether or not the US government will begin regulating drug prices as part of a comprehensive healthcare reform package. As many of you may know, the US government, unlike most other governments in the world, cannot negotiate or set prescription drugs prices. Not surprisingly, the US prescription drug market is the largest and most profitable in the world. It will be interesting to see how the US healthcare reform discussion unfolds—clearly a lot is at stake for the American prescription drug industry.

Until next time...

Good Luck and Good Job Hunting!!!!!!!!!

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A Web-Based Map Application that Track Infectious Diseases Outbreaks

Vincent Racaniello, my partner at BioCrowd, and I were chatting the other day about how cool it would be to develop a web-based map that was able to track infectious diseases outbreaks in real time. After a spirited chat, we both thought that we were on to something REALLY big. And, as is frequently the case, somebody else also had the very same idea.

For those infectious disease aficionados out there, you must check out the Health Map: A Global Disease Alert Map. The map was developed by Clark Freifeld and John Brownstein and is based on an algorithm that is beyond my comprehension. It is not as robust as the map that Vincent and I envisioned, but it is pretty cool and it works very nicely.

Until next time…

Good Luck and Good Disease Hunting!!!!!!!

 

 

The World's Best Places For Small Businesses

 

Each year the World Bank compiles a report that assesses the world’s friendliest business climates for small companies. The top three companies on this year’s list, Singapore, New Zealand and the US have been there four years in a row. The real shocker this year was that several previously lagging nations moved up on the list, mostly because of business-friendly reforms. This year’s most improved nation is Azerbaijan, which moved up 64 spots to a overall ranking of 33rd because it reduced the time required to start a new business from 122 to 16 days, reforming its civil code and creating an online tax filing system.

Singapore has habitually been number one on the list because of its low import and export costs, strong government-imposed legal protections for investors and lopsided, employer-friendly labor regulations. The US placed high on the list because its labor laws are among the least rigid in the world and because business can be started quickly with a minimum amount of “red tape”.

For those of you who may be interested the top ten list looks like this:

  1. Singapore
  2. New Zealand
  3. United States
  4. Hong Kong
  5. Denmark
  6. The United Kingdom
  7. Ireland
  8. Canada
  9. Australia
  10. Norway

To see the rest of the list and find out more about starting a small business in your own click here

Until next time…

Good Luck and Good Job Hunting (why not start one?)

 

June 2008-Web Picks

Kevin’s selections this month contains a wide variety of sites ranging from an Australian museum guide, to wildlife parks in Tasmania and online information-sharing and management capabilities.  If leeches are your thing check out this site and if you are a dragonfly aficionado this site will do the trick. An interesting site called the Fallacy Files provides insight into fallacies or so-called mistakes in reasoning.

As a sometimes medical writer, the site that piqued my interest was www.connotea.org— an online reference and information sharing-service.  The site provides you with easy and ready access to references, data and other information stored in your account on the site.  Kevin really likes this site and says “Connotea scores big time with this valuable tool for scientists.”  Check it out….

Until next time….

Good Luck and Good Web Surfing